【Animal Modeling】-Effects of C. chinensis mediated IκB-α phosphorylation on CCl4-induced hepatic fibrosis in rats

　　Objective To investigate the effect of IκB-α and its phosphorylation to down-regulate the nuclear transcription factor signaling pathway to reduce carbon tetrachloride-induced liver fibrosis in C. chinensis. 　　Methods The CCl4 liver fibrosis rat...

2022-06-16

【Animal modeling】-Effect of Ginkgo Mihuan oral solution on the angiogenesis ability of myocardial microvascular endothelial cells in rats

To observe the effects of Ginkgo Mihuan oral solution (referred to as Ginkgo biloba) on the proliferation, migration, cell tubule formation and protein expression of VEGF (vascular endothelial growth factor) and CD31 (platelet-endothelial cell adhesi...

2022-06-16

【Animal modeling】-The effect of membranous cells on chemotherapy-injured granulosa cells and the intervention effect of Zuogui Pill-containing serum

To investigate the effect of membranous cells on chemotherapy-injured granulosa cells and the intervention effect of Zuogui Pill-containing serum...

2022-06-16

【Animal Modeling】-Analysis of the effects of different hypoxia exposure modes on differential gene expression of rat tibialis anterior muscle based on RNA sequencing

To screen the differentially expressed genes and their related pathways in rat tibialis anterior muscle from chronic intermittent hypoxia exposure and acute hypoxia exposure...

2022-06-16

【Animal modeling】-Effect of Jiayankangtai granules on immune-related cytokines in autoimmune thyroiditis rats

To detect the effect of Jiayankangtai granules on immune-related cytokines in autoimmune thyroiditis rats, and to explore the mechanism of Jiayankangtai granules in improving autoimmune thyroiditis...

2022-06-16

To explore the effect of Bushen Yiqi Huayu Granule on angiogenesis in osteoporosis rats based on TLRs/NF-κB signaling pathway

To explore the effect of Bushen Yiqi Huayu Granule on angiogenesis in osteoporosis rats based on TLRs/NF-κB signaling pathway...

2022-06-16

【Animal modeling】-Kallikrein alleviates oxidative stress and fibrosis in rats with myocardial ischemia-reperfusion injury

To investigate the effect of pancreatic kininogenase on myocardial injury, oxidative stress and fibrosis in rats with myocardial ischemia-reperfusion injury...

2022-06-16

【Animal modeling】-1,25(OH)2 D3 protects thyroid function in rats with experimental autoimmune thyroiditis by inhibiting TLR2/NF-κB signaling pathway

To study the protective mechanism of 1,25(OH)2D3 on experimental autoimmune thyroiditis rats based on TLR2/NF-κB signaling pathway...

2022-06-16

【Animal Modeling】-The effect of environmental enrichment on stress-related indicators in British Shorthair cats

To study the alleviating effect of environmental enrichment on the stress response of experimental British Shorthair cats...

2022-06-16

【Animal modeling】-Based on autophagy to investigate the effect of fentanyl combined with propofol on cardiac ischemia-reperfusion injury in rats

To investigate the effect of fentanyl combined with propofol on cardiac ischemia-reperfusion injury in rats based on autophagy...

2022-06-16

【Animal modeling】-The regulatory effect of curcumin and/or aerobic exercise on intestinal function in rats with dyslipidemia

To investigate the regulatory effect of curcumin and/or aerobic exercise on intestinal function in rats with dyslipidemia...

2022-06-16

【Animal Modeling】-Effects of MED1 deletion in macrophages on blood glucose levels and insulin resistance in mice

To study the regulatory role of macrophage MED1 in the occurrence of insulin resistance...

2022-06-16

【Animal Modeling】-Effect of Compound Microecological Preparations on Intestinal Immune Function in Mice

To study the effect of compound probiotics on intestinal mucosal immune function in mice...

2022-06-16

To investigate the effect of atorvastatin on myelin repair and RhoA/Rock1 pathway in autoimmune encephalomyelitis (EAE) mice

To investigate the effect of atorvastatin on myelin repair and RhoA/Rock1 pathway in autoimmune encephalomyelitis (EAE) mice...

2022-06-16

【Animal modeling】-Protective effect of Dahuang Mudan decoction on liver injury in rats with acute pancreatitis

To investigate the protective effect of Dahuang Mudan Decoction on liver injury in rats with acute pancreatitis...

2022-06-16

【Animal modeling】-In vitro differentiation of mouse umbilical cord mesenchymal stem cells

To isolate and expand mouse umbilical cord mesenchymal stem cells to investigate whether they can be induced into cartilage, adipose and osteoblasts...

2022-06-15