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[Animal Modeling]-Chronic renal failure model established by chemical methods

[Animal Modeling]-Chronic renal failure model established by chemical methods

Replication method Adult rats weighing about 250g are anesthetized by injecting pentobarbital sodium at a dose of 30 mg/kg body weight into the abdominal cavity. After anesthesia, the rats are fixed on the operating board on their back, and the abdom...

2021-11-01
Mouse intestinal experiments reveal a new computer model that may monitor the dynamics of the intestinal flora after infection

Mouse intestinal experiments reveal a new computer model that may monitor the dynamics of the intestinal flora after infection

Infectious diseases often make us feel uncomfortable. Recently, in a research paper published in the international journal PLoS ONE, researchers from Brigham and Women’s Hospital used a special computer model to reveal that infections affect the natu...

2021-11-01
【Animal Modeling】-Hypertensive model caused by medullary nerve compression

【Animal Modeling】-Hypertensive model caused by medullary nerve compression

Copy method After conventional anesthesia, the trachea is intubated into the adult experimental dog and into the right femoral artery, and the blood pressure is monitored with a multi-channel physiological recorder...

2021-11-01
[Animal modeling]-The protective effect of camel milk on DSS-induced acute enteritis in mice

[Animal modeling]-The protective effect of camel milk on DSS-induced acute enteritis in mice

To explore the protective effect of camel milk on acute enteritis induced by dextran sulfate sodium sulfate (DSS) in mice...

2021-11-01
[Animal Modeling]-Effect of Ligustrazine on Extracellular Regulated Protein Kinase Pathway in Collagen-induced Arthritis Rats

[Animal Modeling]-Effect of Ligustrazine on Extracellular Regulated Protein Kinase Pathway in Collagen-induced Arthritis Rats

To explore the effect of Linagliptin on extracellular regulatory protein kinase (ERK) pathway in collagen-induced arthritis rats...

2021-11-01
How gene therapy treats fatal heart disease

How gene therapy treats fatal heart disease

Danon disease is a very rare life-threatening disease. Its cause is the loss of function of the system responsible for removing and recycling proteins in cells, which will further lead to the function of the heart, skeletal muscle, nervous system, ey...

2021-11-01
Establishment of Potentilla anserine myocardial infarction model and analysis of gene expression profile in infarct marginal zone

Establishment of Potentilla anserine myocardial infarction model and analysis of gene expression profile in infarct marginal zone

Use Potentilla chinensis minipigs and clinically important model indicators to establish a myocardial infarction (myocardial infarction) model, and study the correlation between gene expression and metabolic compensation in the area around myocardial...

2021-11-01
[Animal Modeling]-Inhibitory effect of ursolic acid on rat corneal transplant rejection

[Animal Modeling]-Inhibitory effect of ursolic acid on rat corneal transplant rejection

To explore the therapeutic effect of ursolic acid on rat corneal transplant rejection...

2021-11-01
【Animal Modeling】-The effect of a single intraosseous injection of low-dose simvastatin on angiogenesis after myocardial infarction in rats

【Animal Modeling】-The effect of a single intraosseous injection of low-dose simvastatin on angiogenesis after myocardial infarction in rats

To study the effect of a single local injection of low-dose simvastatin in bone on angiogenesis and cardiac function after myocardial infarction in rats...

2021-11-01
【Animal Modeling】-Adenine-induced Chronic Kidney Disease Rat Model

【Animal Modeling】-Adenine-induced Chronic Kidney Disease Rat Model

Observe the characteristics of mineral metabolism biochemical markers in adenine-induced chronic kidney disease rat model, vascular calcification and renal bone disease?...

2021-11-01
Preclinical safety analysis of rodents and non-human primates

Preclinical safety analysis of rodents and non-human primates

Fibroblast growth factor receptor 1 (FGFR1) belongs to the cell surface FGF receptor family expressed by a certain number of normal tissues, but it is highly amplified and overexpressed in some solid tumors (such as lung cancer and breast cancer)...

2021-11-01
[Animal Experiment]-Use zebrafish to study gene mutations that cause congenital scoliosis

[Animal Experiment]-Use zebrafish to study gene mutations that cause congenital scoliosis

Zebrafish are popular in aquariums around the world and are native to South Asia. However, at the Cincinnati Children’s Institute, the freshwater mutants here play an important role in scientific discoveries...

2021-11-01
How to establish an in vitro apoptosis model of intervertebral disc nucleus pulposus cells? -【Animal Modeling】

How to establish an in vitro apoptosis model of intervertebral disc nucleus pulposus cells? -【Animal Modeling】

Establishment of an in vitro apoptosis model of rat intervertebral disc nucleus pulposus cells...

2021-11-01
Study on the optimization plan of the animal model of Ureaplasma urealyticum infection

Study on the optimization plan of the animal model of Ureaplasma urealyticum infection

Explore the advantages and disadvantages of different modeling methods, and select the most suitable animal model method for Ureaplasma urealyticum infection...

2021-11-01
【Animal Modeling】-How to build a mouse orthotopic transplantation tumor model of human-derived liver cancer cells?

【Animal Modeling】-How to build a mouse orthotopic transplantation tumor model of human-derived liver cancer cells?

Choose 3 strains of human liver cancer cells, inoculate 4 different types of different immunodeficiency mouse liver tissues in situ, establish the orthotopic transplantation model of human liver cancer cells and compare them?...

2021-11-01
【Animal Modeling】-How to establish a mouse model of chronic thrombosis?

【Animal Modeling】-How to establish a mouse model of chronic thrombosis?

The mice were treated by continuous intraperitoneal injection of different concentrations of carrageenan solution, and the disease condition of the mouse model of chronic thrombosis was screened....

2021-11-01
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