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【Animal modeling】-Application of reduced glutathione in biological purification and rapid reproduction of AG129 mice

【Animal modeling】-Application of reduced glutathione in biological purification and rapid reproduction of AG129 mice

AG129 mice are difficult to give birth naturally, and conventional in vitro fertilization reagents cannot be used to obtain enough embryos for transplantation...

2022-10-11
【Animal modeling】-Effect of Helicobacter hepatica infection on dextran sulfate sodium-induced chronic colitis model in mice

【Animal modeling】-Effect of Helicobacter hepatica infection on dextran sulfate sodium-induced chronic colitis model in mice

To investigate the effect of Helicobacter hepatica infection on chronic colitis induced by sodium dextran sulfate in mice...

2022-10-11
【Animal Modeling】-Preparation and Breeding of FAH Gene Knockout Cloned Miniature Pigs

【Animal Modeling】-Preparation and Breeding of FAH Gene Knockout Cloned Miniature Pigs

The shortage of donors is the main problem faced by organ transplantation, and the preparation of humanized organs is one of the effective ways to solve this problem...

2022-10-11
【Animal modeling】-The neuroprotective effect of erythropoietin in a rat model of hypoxic-ischemic encephalopathy

【Animal modeling】-The neuroprotective effect of erythropoietin in a rat model of hypoxic-ischemic encephalopathy

To make a hypoxic-ischemic encephalopathy model in neonatal rats, to study the cerebral protective effect of recombinant human erythropoietin (EPO) and the changes of HIE intestinal flora diversity in neonatal rats, for clinical application of EPO in...

2022-10-10
【Animal Modeling】-Oriented breeding and identification of Mfge8 knockout homozygous mice and their correlation with autoimmune diseases

【Animal Modeling】-Oriented breeding and identification of Mfge8 knockout homozygous mice and their correlation with autoimmune diseases

To breed and identify Mfge8 knockout C57BL/6 mice, obtain homozygous (Mfge8-/-) mice, and compare the serological and histological changes of Mfge8-/- mice...

2022-10-10
【Animal Modeling】-Study on the correlation between SLC1A2 gene SNP locus and the activity of Labrador retrievers and golden retrievers

【Animal Modeling】-Study on the correlation between SLC1A2 gene SNP locus and the activity of Labrador retrievers and golden retrievers

To detect the correlation between the SNP locus of SLCIA2 gene and the activity of Labrador retrievers and golden retrievers, in order to screen effective genetic molecular markers for the early selection and breeding of guide dogs...

2022-10-10
【Animal Modeling】-Zucker Diabetic Obesity Rats Cerebrovascular Disease Characteristics and Pathogenesis Study

【Animal Modeling】-Zucker Diabetic Obesity Rats Cerebrovascular Disease Characteristics and Pathogenesis Study

To observe the pathological characteristics of cerebrovascular disease in Zucker diabetic obese (ZDF) rats, and to preliminarily explore its pathogenesis, so as to provide experimental basis and theoretical basis for the application of ZDF rats...

2022-10-10
【Animal modeling】-Effect of knockout TRPC6 on MPTP-induced neuroinflammatory injury in mice

【Animal modeling】-Effect of knockout TRPC6 on MPTP-induced neuroinflammatory injury in mice

To detect the expression of TRPC6 channel in microglia in a mouse MPTP-induced neuroinflammation model, and to explore the effect of TRPC6 channel on inflammatory expression and dopaminergic neuron damage...

2022-10-10
【Animal Modeling】-Effect of high-fat diet on insulin resistance and expression of hepatic insulin receptor substrate 1 and 2 in Tibetan miniature pigs

【Animal Modeling】-Effect of high-fat diet on insulin resistance and expression of hepatic insulin receptor substrate 1 and 2 in Tibetan miniature pigs

To investigate the effect of high-fat diet on insulin resistance (IR) and the expression of hepatic insulin receptor substrate (IRS) 1 and 2 in Tibetan miniature pigs...

2022-10-10
【Animal modeling】-Analysis of the effect of portal hypertension on serum endotoxin and intestinal mucosa in rats

【Animal modeling】-Analysis of the effect of portal hypertension on serum endotoxin and intestinal mucosa in rats

To study the effect of simple portal hypertension on serum endotoxin and intestinal mucosa in rats?...

2022-10-10
【Animal Modeling】-Diagnosis of Spontaneous Diabetic Cynomolgus Monkeys and Changes in Bone Microstructure

【Animal Modeling】-Diagnosis of Spontaneous Diabetic Cynomolgus Monkeys and Changes in Bone Microstructure

To diagnose spontaneously diabetic cynomolgus monkeys and analyze the changes of their bone microstructure, in order to establish an animal model of spontaneous diabetes mellitus complicated with osteoporosis...

2022-10-10
【Animal Modeling】- Improvement of Rat Cerebrospinal Fluid Extraction by Negative Pressure Suction Device

【Animal Modeling】- Improvement of Rat Cerebrospinal Fluid Extraction by Negative Pressure Suction Device

To improve the extraction of cerebrospinal fluid from rats by negative pressure suction device, and to further improve the success rate of cerebrospinal fluid collection in rats...

2022-10-10
【Animal modeling】-The improvement effect of Xueshuantong capsule on tight junction injury of HUVEC cells induced by oxygen-glucose deprivation/reoxygenation

【Animal modeling】-The improvement effect of Xueshuantong capsule on tight junction injury of HUVEC cells induced by oxygen-glucose deprivation/reoxygenation

To investigate the protective effect of Panax notoginseng saponins (PNS) and its monomers Rg1-Rb1 on the damage of vascular endothelial tight junctions induced by oxygen-glucose deprivation (OGD) in a model of HUVEC cells induced by oxygen-glucose de...

2022-10-10
【Animal Modeling】-The effect of experimental intervention of physiological saline on the caecal microflora and short-chain fatty acid content of broilers

【Animal Modeling】-The effect of experimental intervention of physiological saline on the caecal microflora and short-chain fatty acid content of broilers

To study the effect of physiological saline intervention on the intestinal flora and short-chain fatty acid content of broiler chickens, to provide specific basis for early microbial intervention experimental research?...

2022-10-10
【Disease Animal Model】-Radiation Cataract Animal Model

【Disease Animal Model】-Radiation Cataract Animal Model

  Ultraviolet rays (UV) in nature are divided into UVA (315-400m), UVB (280-315m) and UVC (100-280m)...

2022-10-10
【Animal modeling】-Correlation analysis of miRNA and mRNA expression profiles in oral and buccal mucosal carcinoma of Chinese hamster

【Animal modeling】-Correlation analysis of miRNA and mRNA expression profiles in oral and buccal mucosal carcinoma of Chinese hamster

To construct the differentially expressed miRNA and mRNA expression profiles in Chinese hamster oral buccal carcinoma (OSCC), and preliminarily predict the miRNA and mRNA related to the occurrence and development of OSCC...

2022-10-10