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【Animal modeling】-The effect of vasoactive intestinal peptide on the prevention and treatment of experimental autoimmune encephalomyelitis by regulating the balance of CD4+CD25+Treg/Th17

【Animal modeling】-The effect of vasoactive intestinal peptide on the prevention and treatment of experimental autoimmune encephalomyelitis by regulating the balance of CD4+CD25+Treg/Th17

To investigate the effect of vasoactive intestinal peptide regulating the balance of CD4+CD25+Treg/Th17 on the prevention and treatment of experimental autoimmune encephalomyelitis...

2023-02-28
【Animal Modeling】-Effects of combined anesthesia with thiolazine and ketamine on blood pressure and pulse of fernma miniature pigs

【Animal Modeling】-Effects of combined anesthesia with thiolazine and ketamine on blood pressure and pulse of fernma miniature pigs

Fern Ma pig, also known as cooperative pig and mountain pig, is a small, excellent and unique local pig breed cultivated by the local Tibetan people in Gannan in a harsh natural environment at an altitude of about 3000 m in a free-range manner [1]. F...

2023-02-28
【Animal modeling】-PCR detection and analysis of various bacteria in experimental rats and mice

【Animal modeling】-PCR detection and analysis of various bacteria in experimental rats and mice

To investigate the bacterial carriage status of rats and mice in Shanghai laboratory animal production facilities...

2023-02-27
【Animal Modeling】-Optimization of the detection method of Pasteurella pneumophila in mice and drug purification of infected mice

【Animal Modeling】-Optimization of the detection method of Pasteurella pneumophila in mice and drug purification of infected mice

To optimize the detection method of Pasteurella pneumophila in mice, improve the detection sensitivity to strengthen the daily monitoring of Pasteurella pneumophila, and explore the feasibility of drug purification in infected mice...

2023-02-27
【Animal Modeling】-Establishment of an animal model of neuroblastoma adrenal orthotopic transplantation

【Animal Modeling】-Establishment of an animal model of neuroblastoma adrenal orthotopic transplantation

To establish an animal model of neuroblastoma adrenal orthotopic transplantation, and to explore its advantages over the traditional subcutaneous ectopic tumor transplantation model...

2023-02-27
【Animal modeling】-Research on the curative effect and recurrence of GnRH-a plus estrogen on rat endometriosis model

【Animal modeling】-Research on the curative effect and recurrence of GnRH-a plus estrogen on rat endometriosis model

To investigate the therapeutic effect of GnRH-a plus different doses of estrogen on endometriosis and its effect on recurrence...

2023-02-27
【Animal modeling】-The protective effect of etomidate on acute lung injury in septic shock rats based on TLR4 pathway

【Animal modeling】-The protective effect of etomidate on acute lung injury in septic shock rats based on TLR4 pathway

To investigate the protective effect of etomidate (Eto) on acute lung injury in rats with septic shock based on the Toll-like receptor 4 (TLR4) pathway...

2023-02-27
【Animal Modeling】-Study on Autoimmune Premature Ovarian Failure Model

【Animal Modeling】-Study on Autoimmune Premature Ovarian Failure Model

In order to better establish an autologous premature ovarian failure model, different modeling time and adjuvant were used to observe the related factors of ZP3-induced immune premature ovarian failure model...

2023-02-27
【Animal modeling】-Establishment and application of immunocomb detection method for simian immunodeficiency virus antibody

【Animal modeling】-Establishment and application of immunocomb detection method for simian immunodeficiency virus antibody

To prepare the SIV30 protein of simian immunodeficiency virus (SIV) by genetic engineering technology as an antigen diagnostic reagent, and to establish an immunocomb method (IC) for the specific detection of anti-SIV antibody IgG in the serum of exp...

2023-02-27
【Animal modeling】-The expression levels and significance of Maspin and IKKα in the sinus mucosa of rats with fungal sinusitis

【Animal modeling】-The expression levels and significance of Maspin and IKKα in the sinus mucosa of rats with fungal sinusitis

To investigate the expression levels and significance of Maspin and IKKα in the sinus mucosa of rats with fungal rhinosinusitis (FRS)...

2023-02-27
【Animal modeling】-Characteristics of liver pathological damage in db/db mice with spontaneous type 2 diabetes

【Animal modeling】-Characteristics of liver pathological damage in db/db mice with spontaneous type 2 diabetes

To dynamically observe the pathological changes and characteristics of the liver of db/db mice with spontaneous type 2 diabetes mellitus, and to provide the basic theory and experimental basis for the experimental study of using the liver of db/db mi...

2023-02-27
【Animal Modeling】-Diagnosis of Spontaneous Diabetic Cynomolgus Monkeys and Changes in Bone Microstructure

【Animal Modeling】-Diagnosis of Spontaneous Diabetic Cynomolgus Monkeys and Changes in Bone Microstructure

To diagnose spontaneously diabetic cynomolgus monkeys and analyze the changes of their bone microstructure, in order to establish an animal model of spontaneous diabetes mellitus complicated with osteoporosis...

2023-02-27
【Animal Modeling】-Proliferation of umbilical cord mesenchymal stem cells on dairy bovine mammary epithelial cells under serum-free co-culture conditions

【Animal Modeling】-Proliferation of umbilical cord mesenchymal stem cells on dairy bovine mammary epithelial cells under serum-free co-culture conditions

To investigate the proliferation effect of umbilical cord mesenchymal stem cells on dairy bovine mammary epithelial cells under serum-free co-culture conditions...

2023-02-27
【Animal modeling】-Establishment of acute and chronic hyperuricemia models

【Animal modeling】-Establishment of acute and chronic hyperuricemia models

To establish acute mouse and chronic rat hyperuricemia models, and use positive drugs to verify the curability of the two models, so as to provide model tools for the development of anti-hyperuric acid drugs...

2023-02-27
【Animal Modeling】-Construction of an experimental autoimmune myasthenia gravis mouse model using the black-spotted double-fin electric ray

【Animal Modeling】-Construction of an experimental autoimmune myasthenia gravis mouse model using the black-spotted double-fin electric ray

To establish an experimental autoimmune myasthenia gravis animal model that meets international preclinical experimental standards...

2023-02-23
【Animal modeling】-Transcriptome analysis of colon tissue of IBD mice under the intervention of mesalazine

【Animal modeling】-Transcriptome analysis of colon tissue of IBD mice under the intervention of mesalazine

To use transcriptome sequencing technology to detect the changes of gene expression in colon tissue of mice with inflammatory bowel disease, and to improve the understanding of the molecular mechanism of mesalazine in the treatment of IBD...

2023-02-23