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【Animal modeling】-Effect of astragaloside Ⅱ on IL-21/STAT3 pathway and airway inflammation in juvenile asthmatic rats

【Animal modeling】-Effect of astragaloside Ⅱ on IL-21/STAT3 pathway and airway inflammation in juvenile asthmatic rats

To investigate the effect of astragaloside Ⅱ on interleukin-21 ( IL-21 ) / signal transducer and activator of transcription 3 ( STAT3 ) pathway and airway inflammation in juvenile asthmatic rats...

2023-03-02
【Animal modeling】-Effect of paclitaxel on the expression of CD28, CTLA-4 and BAFF in experimental autoimmune encephalomyelitis rats

【Animal modeling】-Effect of paclitaxel on the expression of CD28, CTLA-4 and BAFF in experimental autoimmune encephalomyelitis rats

To investigate the effect of paclitaxel on the expression of CD28 and CTLA-4 in the brain tissue of rats with experimental autoimmune encephalomyelitis and the content of B cell stimulating factor (BAFF) in the supernatant of spleen tissue and its si...

2023-03-02
【Animal modeling】-Effect of cigarette smoke exposure on plasma nicotine and cotinine in male rats

【Animal modeling】-Effect of cigarette smoke exposure on plasma nicotine and cotinine in male rats

To investigate the internal exposure level of cigarettes in vivo by measuring the plasma nicotine and cotinine contents in smoking rats...

2023-03-02
【Animal Modeling】-improved New Zealand Rabbit Common Carotid Artery Cannulation Fixation Method

【Animal Modeling】-improved New Zealand Rabbit Common Carotid Artery Cannulation Fixation Method

To investigate a stable, not easy to fall off, and continuous and timed blood collection method for the common carotid artery cannulation of New Zealand rabbits...

2023-03-02
【Animal Modeling】-Experimental Study on Mussel Mucin Adhesion and Antioxidant Effect on Ulcerative Colitis in Rats

【Animal Modeling】-Experimental Study on Mussel Mucin Adhesion and Antioxidant Effect on Ulcerative Colitis in Rats

To observe the effect of mussel mucin (MAP) on the intestinal mucosa of rats with ulcerative colitis, and to explore its mechanism from the perspective of adhesion and anti-oxidation...

2023-03-01
【Animal Modeling】-Effect of Protein Phosphatase 5 (PP5) on Fat Metabolism in Mice

【Animal Modeling】-Effect of Protein Phosphatase 5 (PP5) on Fat Metabolism in Mice

To explore the role of PP5 in fat metabolism in mice using protein phosphatase 5 knockout mice...

2023-03-01
【Animal Modeling】- Improvement of the method of preventing the displacement of the implanted dilator in the sarcoma and deep fascia of the experimental rabbit

【Animal Modeling】- Improvement of the method of preventing the displacement of the implanted dilator in the sarcoma and deep fascia of the experimental rabbit

To investigate the method of preventing the displacement of the implanted dilator in the sarcoid and deep fascia of rabbits...

2023-03-01
【Animal modeling】-The role and mechanism of miR-221 in H2O2-induced myocardial cell injury in rats

【Animal modeling】-The role and mechanism of miR-221 in H2O2-induced myocardial cell injury in rats

To investigate the role and mechanism of miR-221 in hydrogen peroxide (H2O2)-induced myocardial cell injury in rats...

2023-03-01
【Animal modeling】-Application of three mouse enterovirus nucleic acid detection technologies in mouse health monitoring

【Animal modeling】-Application of three mouse enterovirus nucleic acid detection technologies in mouse health monitoring

To use nucleic acid detection technology to detect MHV, Reo-3 and MNV enteroviruses in cecal contents of mice, and to compare the results with serological detection results to analyze the applicability of nucleic acid detection in mouse health monito...

2023-03-01
【Animal modeling】-The expression levels and significance of Maspin and IKKα in the sinus mucosa of rats with fungal sinusitis

【Animal modeling】-The expression levels and significance of Maspin and IKKα in the sinus mucosa of rats with fungal sinusitis

To investigate the expression levels and significance of Maspin and IKKα in the sinus mucosa of rats with fungal rhinosinusitis (FRS)...

2023-03-01
【Animal modeling】-Protective effect of Src kinase inhibitor PP2 on hypoxia/reoxygenation injury of rat astrocytes

【Animal modeling】-Protective effect of Src kinase inhibitor PP2 on hypoxia/reoxygenation injury of rat astrocytes

To investigate the protective effect of Src kinase inhibitor PP2 on hypoxia/reoxygenation injury of rat astrocytes...

2023-03-01
【Animal modeling】-Dynamic changes of tumor-infiltrating immune cells in MC38 colon cancer mice

【Animal modeling】-Dynamic changes of tumor-infiltrating immune cells in MC38 colon cancer mice

To observe the dynamic changes of tumor-infiltrating immune cells during tumor development in tumor-bearing mice...

2023-02-28
【Animal Modeling】-Influenza virus model preparation technology

【Animal Modeling】-Influenza virus model preparation technology

1. According to its pathogenicity to poultry, avian influenza can be divided into three levels: high pathogenicity, low pathogenicity and non-pathogenicity. Among them, highly pathogenic avian influenza has two subtypes, H5 and H7, but not all H5 and...

2023-02-28
【Animal modeling】-Effect of Roux-en-Y gastric bypass on liver and peripheral insulin sensitivity in type 2 diabetic rats

【Animal modeling】-Effect of Roux-en-Y gastric bypass on liver and peripheral insulin sensitivity in type 2 diabetic rats

To observe the changes of insulin sensitivity in the liver and peripheral tissues of type 2 diabetic rats at different times after RYGB and to preliminarily explore the possible mechanism...

2023-02-28
【Animal modeling】-Analysis of the effects of two reoviruses on the intestinal flora of mice based on 16S rRNA sequencing

【Animal modeling】-Analysis of the effects of two reoviruses on the intestinal flora of mice based on 16S rRNA sequencing

To investigate the effects of two reoviruses, T1L and NBV, on the structure of intestinal flora in mice...

2023-02-28
【Animal modeling】-Comparative study on blood physiological and biochemical indexes of normal Bama miniature pigs and F5 generation of hyperglycemic families

【Animal modeling】-Comparative study on blood physiological and biochemical indexes of normal Bama miniature pigs and F5 generation of hyperglycemic families

To compare and analyze the blood physiological and biochemical indicators of normal Bama miniature pigs and F5 individuals of hyperglycemic families...

2023-02-28