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Lipophagy is a selective autophagy targeting fat and is regulated by FoxO1. As an effective means of regulating lipid metabolism disorders, there is no report on whether exercise is related to FoxO1-lipophagy process in hyperlipidemia....
2023-01-31Feeding method Anesthetized adult experimental rats with 30 mg/kg body weight of pentobarbital sodium injected intraperitoneally without ascites after fasting for 24 hours are placed in a hot water bath at 80-92°C for 10-18 seconds...
2023-01-31Explore the effects of all-trans retinoic acid (ATRA) on type II collagen (CII)-induced rheumatoid arthritis (CIA) rat arthritis formation stage joint tissue structure, serum expression of related inflammatory cytokines, and cartilage damage Influenc...
2023-01-31Use BALB/c nude mice to establish M1 leukemia model?...
2023-01-30Try to use ovalbumin in combination with smoking to establish a more similar guinea pig CVA model...
2023-01-30To observe the effect of different concentrations of baicalin (baicalin) on experimental autoimmune encephalomyelitis mouse model, and to study its preliminary mechanism...
2023-01-30To observe the intervention effect of electroacupuncture on the nuclear transcription factor κBp65 protein in the spinal dorsal horn of rats with diabetic neuralgia, so as to explore the partial analgesic mechanism of electroacupuncture in diabetic n...
2023-01-29To observe the relationship between peripheral TRPV1 and P2X3 in rats, in order to partially elucidate the regulatory mechanism of peripheral pain sensation...
2023-01-29To study the effects of five kinds of ferula from Xinjiang and their different polar parts on the proliferation inhibition and apoptosis of human colon cancer HCT 116 cells in vitro, and to study the effects of five kinds of ferula from Xinjiang on c...
2023-01-29To explore the effect of cannabinol on monoamine neurotransmitters in the central nervous system in methamphetamine dependent rats, explain the therapeutic mechanism of CBD on METH dependence, and provide reference for the development of drug depende...
2023-01-29To investigate the effect of Kaixinsan on the injection of A into bilateral hippocampal CA1 region β The therapeutic effect of 1-42 on AD rats, and its mechanism of action is preliminarily clarified...
2023-01-29To establish a related mouse knee osteoarthritis model by knocking out SIRT1 gene, and to observe the differences in the morphology of cartilage tissue sections with different single staining or compound staining techniques...
2023-01-29Osteoporosis model constructed with ovariectomized rats is the most suitable model to study postmenopausal osteoporotic disease, however, the effect on skin after ovary removal in rats is seldom studied....
2023-01-29
A few days ago, the Institute of Neuroscience of Soochow University and Professor Hua Yimin of Cold Spring Harbor Laboratory in the United States developed a number of mouse disease models, which effectively increased the expression of motor neuron s...
2023-01-18Memory CD4 T cells and macrophages are the main host and cell bank of humans and HIV in non-human primates...
2023-01-18To investigate the effect of hydrogen-rich solution on the apoptosis of hippocampal neurons and the expression of PI3K/Akt/FoxO1 signaling pathway induced by cerebral ischemia-reperfusion in rats...
2023-01-18