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【Animal Modeling】-Effect and mechanism of acute liver injury in mice on brown adipose tissue function

【Animal Modeling】-Effect and mechanism of acute liver injury in mice on brown adipose tissue function

To investigate the effects of carbon tetrachloride (CC14)-induced acute liver injury on brown adipose tissue in mice at different time points and related mechanisms...

2022-01-10
【Animal modeling】-The role of up-regulation of p-CaMKⅡ expression in dorsal root ganglion in rats with diabetic neuralgia

【Animal modeling】-The role of up-regulation of p-CaMKⅡ expression in dorsal root ganglion in rats with diabetic neuralgia

To observe the expression of phosphorylated calcineurin II (p-CaMK II) in the dorsal root ganglion (DRG) of diabetic neuropathic pain model rats at different stages...

2022-01-10
【Animal modeling】-Effect of astragaloside IV on inflammatory factors and ultrastructure in cerebral ischemia-reperfusion rats

【Animal modeling】-Effect of astragaloside IV on inflammatory factors and ultrastructure in cerebral ischemia-reperfusion rats

To observe the effect of astragaloside IV on inflammatory factors and ultrastructure in cerebral ischemia-reperfusion rats...

2022-01-10
【Animal Modeling】-Urinary Tract Stone Rat Model

【Animal Modeling】-Urinary Tract Stone Rat Model

Male Wistar rats weighing 180-220 g were randomly divided into several groups and fed with normal diet. Before the end of the experiment, a metabolic cage was used to collect and measure the 24-hour urine output and 24-hour oxalic acid (Ox)...

2022-01-07
【Animal Modeling】-Animal Model of Foot-and-Mouth Disease Virus

【Animal Modeling】-Animal Model of Foot-and-Mouth Disease Virus

The replication method uses 0.01 mol/L PBS (pH 7.4) to dilute the foot-and-mouth disease seed virus ORMF8 to LD50 to 10-3 to 10-7/0.2 ml, and then titrate each titer of virus solution dilution. The guinea pig is injected intracutaneously into the toe...

2022-01-07
[Animal Modeling]-Chronic Renal Failure

[Animal Modeling]-Chronic Renal Failure

Chronic renal failure caused by rat freezing [Surgical procedure] Male rats 200-300 g (proteinuria was not measured before surgery). After anesthesia, cut the left side of the abdomen to expose the left side and expose the kidney myocardium. Peel off...

2022-01-07
【Animal Modeling】-Changes of Monoamine Transmitter Content and Expression of Neural Factors in the Brain of Rats with Anxiety Depression

【Animal Modeling】-Changes of Monoamine Transmitter Content and Expression of Neural Factors in the Brain of Rats with Anxiety Depression

To study the changes in the levels of monoamine transmitters in the hippocampus, amygdala, and prefrontal cortex and the expression trends of neurotrophic factors in the brain of an anxiety-induced depression model rat, and explore its possible patho...

2022-01-07
[Animal Modeling]-Stem cells can repair the damaged circuit of Parkinson\\\\

[Animal Modeling]-Stem cells can repair the damaged circuit of Parkinson

Due to degenerative diseases such as stroke and Parkinson\\\\\\\'s disease, it is difficult to repair after injury. The unlimited adaptability of stem cells provides hope for better nerve repair...

2022-01-07
[Animal modeling]-Correlation between the expression of BDNF and VEGF in hippocampus and forebrain cortex and depression induced by chronic stress in mice

[Animal modeling]-Correlation between the expression of BDNF and VEGF in hippocampus and forebrain cortex and depression induced by chronic stress in mice

To explore the correlation between brain-derived neurotrophic factor (BDNF) and vascular endothelial growth factor (VEGF) expression in mouse hippocampus and forebrain cortex caused by chronic stress and depression...

2022-01-07
[Animal modeling]-Lateral hydraulic shock brain injury model

[Animal modeling]-Lateral hydraulic shock brain injury model

The lateral hydraulic shock brain injury model quickly injects a certain amount of saline into the cranial cavity, which causes the deformation and displacement of the brain tissue, which leads to TBI...

2022-01-07
What is an animal model of spontaneous liver cirrhosis? -【Animal Modeling】

What is an animal model of spontaneous liver cirrhosis? -【Animal Modeling】

To study the pathological and serum biochemical changes in the liver of Beagle dogs with spontaneous cirrhosis, and to establish background data for experimental animals suitable for GLP...

2022-01-07
【Animal Modeling】-Continuous Glucose Monitoring System in Rabbit Model of Hypoglycemia

【Animal Modeling】-Continuous Glucose Monitoring System in Rabbit Model of Hypoglycemia

Establish a rabbit hypoglycemia model to evaluate the accuracy and timeliness of the continuous subcutaneous blood glucose monitoring system (CGMS) to monitor hypoglycemia...

2022-01-07
【Animal Modeling】-Canine model of portal hypertension with carbon tetrachloride liver cirrhosis

【Animal Modeling】-Canine model of portal hypertension with carbon tetrachloride liver cirrhosis

Breeding method Take 2 ml/kg body weight of CCl4 orally twice a week for adult dogs for the first 12 weeks, orally once a week for 12 weeks, and then use 3% pentobarbital sodium anesthesia after 12 weeks...

2022-01-07
【Animal Modeling】-Animal Model of Hyperuricemia

【Animal Modeling】-Animal Model of Hyperuricemia

Explore a reliable method to establish a rat model of uric acid excretion hyperuricemia, and lay a foundation for studying the etiology of uric acid excretion hyperuricemia and optimizing the treatment plan...

2022-01-07
【Animal Modeling】-Carotid Artery Balloon Dilation and Restenosis Animal Model

【Animal Modeling】-Carotid Artery Balloon Dilation and Restenosis Animal Model

Copy method After conventional anesthesia, a 3-month-old New Zealand male rabbit was fixed on his back. The neck was cut through a midline incision, and the right common carotid artery (CCA) and internal carotid artery (ICA) were cut. I will It is ex...

2022-01-07
【Animal Modeling】-Effects of Henggu Bone Healing Agent on the Blood Physiology and Organ Coefficient of Fracture Tree Shrew

【Animal Modeling】-Effects of Henggu Bone Healing Agent on the Blood Physiology and Organ Coefficient of Fracture Tree Shrew

To evaluate the effect of transverse bone wound healing agent on the blood physiological indexes and organ coefficients of Tupai castration osteoporotic fracture model...

2022-01-07