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【Animal Modeling】-Study on Periodic Pathological Changes of Chronic Liver Injury in Mice

【Animal Modeling】-Study on Periodic Pathological Changes of Chronic Liver Injury in Mice

To study the characteristics of liver damage in mice with chronic liver disease induced by carbon tetroxide (CCL4), and to explore its application in medical research...

2021-11-02
【Animal Modeling】-Discussion on the Difference of Blood Index of Young SD Rats at Different Stages

【Animal Modeling】-Discussion on the Difference of Blood Index of Young SD Rats at Different Stages

This study aims to collect blood indicators of young SD rats at different developmental stages, establish corresponding background data, and provide references for the safety evaluation of pediatric drugs...

2021-11-02
【Animal Modeling】-SLC1A2 gene SNP locus and Labrador and Golden Retriever activity correlation study

【Animal Modeling】-SLC1A2 gene SNP locus and Labrador and Golden Retriever activity correlation study

To detect the correlation between the SLCIA2 gene SNP locus and the activity of Labrador and Golden Retriever, with a view to screening effective genetic molecular markers for the early selection of guide dogs...

2021-11-02
【Animal Modeling】-Optimization of Mouse Embryo Transfer Technology and Study on Purification of Cytomegalovirus

【Animal Modeling】-Optimization of Mouse Embryo Transfer Technology and Study on Purification of Cytomegalovirus

To establish a purification method for mouse cytomegalovirus to obtain mice without MCMV infection...

2021-11-02
[Animal Modeling]-Behavioral Differences in Learning and Memory Ability of C57BL/6J, BALB/c, ICR Strains of Mice

[Animal Modeling]-Behavioral Differences in Learning and Memory Ability of C57BL/6J, BALB/c, ICR Strains of Mice

Comparison of behavioral differences in the learning and memory ability of C57BL/6J, BALB/c and ICR strains of mice...

2021-11-02
[Animal Modeling]-Mouse Chlamydia trachomatis epididymitis model

[Animal Modeling]-Mouse Chlamydia trachomatis epididymitis model

After the C.trachomatis MoPn Nigg Ⅱ strain was cultured and proliferated on HeLa-229 cells, the infected monolayers were harvested, ultrasonicated for 30 seconds, and centrifuged at 4°C at 500×g for 10 minutes to collect the supernatant. The supernat...

2021-11-01
【Animal Model】- Rat model of cognitive impairment after head injury

【Animal Model】- Rat model of cognitive impairment after head injury

To discuss the preparation and evaluation of animal models of cognitive impairment after head injury...

2021-11-01
【Animal Experiment】-Use the CRISPR/Cas9 system to efficiently edit the Plasmodium genome

【Animal Experiment】-Use the CRISPR/Cas9 system to efficiently edit the Plasmodium genome

Professor Jing Yuan’s team from the School of Life Sciences, Xiamen University uses the CRISPR/Cas9 system to modify multiple genes of different types in the Plasmodium genome, including gene deletion, gene marking and allele substitution...

2021-11-01
[Animal Modeling]-Rat model of high blood flow pulmonary hypertension

[Animal Modeling]-Rat model of high blood flow pulmonary hypertension

Establish a rat model of hyperperfusion pulmonary hypertension with common carotid artery and external carotid anastomosis...

2021-11-01
[Animal Modeling]-Chronic renal failure model established by chemical methods

[Animal Modeling]-Chronic renal failure model established by chemical methods

Replication method Adult rats weighing about 250g are anesthetized by injecting pentobarbital sodium at a dose of 30 mg/kg body weight into the abdominal cavity. After anesthesia, the rats are fixed on the operating board on their back, and the abdom...

2021-11-01
Mouse intestinal experiments reveal a new computer model that may monitor the dynamics of the intestinal flora after infection

Mouse intestinal experiments reveal a new computer model that may monitor the dynamics of the intestinal flora after infection

Infectious diseases often make us feel uncomfortable. Recently, in a research paper published in the international journal PLoS ONE, researchers from Brigham and Women’s Hospital used a special computer model to reveal that infections affect the natu...

2021-11-01
【Animal Modeling】-Hypertensive model caused by medullary nerve compression

【Animal Modeling】-Hypertensive model caused by medullary nerve compression

Copy method After conventional anesthesia, the trachea is intubated into the adult experimental dog and into the right femoral artery, and the blood pressure is monitored with a multi-channel physiological recorder...

2021-11-01
[Animal modeling]-The protective effect of camel milk on DSS-induced acute enteritis in mice

[Animal modeling]-The protective effect of camel milk on DSS-induced acute enteritis in mice

To explore the protective effect of camel milk on acute enteritis induced by dextran sulfate sodium sulfate (DSS) in mice...

2021-11-01
[Animal Modeling]-Effect of Ligustrazine on Extracellular Regulated Protein Kinase Pathway in Collagen-induced Arthritis Rats

[Animal Modeling]-Effect of Ligustrazine on Extracellular Regulated Protein Kinase Pathway in Collagen-induced Arthritis Rats

To explore the effect of Linagliptin on extracellular regulatory protein kinase (ERK) pathway in collagen-induced arthritis rats...

2021-11-01
How gene therapy treats fatal heart disease

How gene therapy treats fatal heart disease

Danon disease is a very rare life-threatening disease. Its cause is the loss of function of the system responsible for removing and recycling proteins in cells, which will further lead to the function of the heart, skeletal muscle, nervous system, ey...

2021-11-01
Establishment of Potentilla anserine myocardial infarction model and analysis of gene expression profile in infarct marginal zone

Establishment of Potentilla anserine myocardial infarction model and analysis of gene expression profile in infarct marginal zone

Use Potentilla chinensis minipigs and clinically important model indicators to establish a myocardial infarction (myocardial infarction) model, and study the correlation between gene expression and metabolic compensation in the area around myocardial...

2021-11-01