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【Animal Modeling】-Comparison of BALB/c mouse bronchial asthma model induced by different doses of egg protein

【Animal Modeling】-Comparison of BALB/c mouse bronchial asthma model induced by different doses of egg protein

To study the effects of different doses of ovalbumin (OVA) on serum IgE, IL-4, IFNγ levels, bronchoalveolar lavage fluid (BALF) and eosinophils (EOS) in BALB/c mouse bronchial asthma model. A more suitable OVA model dose?...

2021-10-27
【Animal Modeling】-Experimental Observation of Porcine Circovirus Type 3 Infection in BALB/c Mice

【Animal Modeling】-Experimental Observation of Porcine Circovirus Type 3 Infection in BALB/c Mice

How to study porcine circovirus 3 (PCV3) infection in BALB/c mice?...

2021-10-27
【Animal Modeling】-Preclinical safety analysis of rodents and non-human primates

【Animal Modeling】-Preclinical safety analysis of rodents and non-human primates

Fibroblast growth factor receptor 1 (FGFR1) belongs to the cell surface FGF receptor family expressed by a certain number of normal tissues, but it is highly amplified and overexpressed in some solid tumors (such as lung cancer and breast cancer)...

2021-10-27
【Animal Modeling】-Experimental method for establishing a full-thickness skin graft model of Wistar rats

【Animal Modeling】-Experimental method for establishing a full-thickness skin graft model of Wistar rats

Introduce an experimental method to establish a full-thickness skin graft model of Wistar rats to improve the success rate of skin graft surgery in Wistar rats...

2021-10-27
【Animal Modeling】-Establishment of Infection and Immunity Model of Physiologically Aging Mice

【Animal Modeling】-Establishment of Infection and Immunity Model of Physiologically Aging Mice

Physiological aging leads to the down-regulation of the immune function of the body, which in turn reduces the immune response of the elderly to infection, and the susceptibility to new and sudden infectious diseases such as severe influenza virus in...

2021-10-27
【Disease Animal Model】-Mini-pig Ⅱ degree root bifurcation defect model

【Disease Animal Model】-Mini-pig Ⅱ degree root bifurcation defect model

A model of Ⅱ degree root bifurcation defect in piglets was established by surgery...

2021-10-27
【Animal Modeling】-Two Compound Models of Hepatitis B and Hepatic Fibrosis in Mice

【Animal Modeling】-Two Compound Models of Hepatitis B and Hepatic Fibrosis in Mice

Combining C57BL/6N-Tg (1.28HBV)/Vst hepatitis B virus transgenic mice and rAAV8-1.3HBV adeno-associated virus transfected mice with intraperitoneal injection of CCl4 to produce type B mice can induce liver fibrosis and Compare the viral and biochemic...

2021-10-27
[Animal Modeling]-Effect of Curcumin on Neutrophils in Blood and Tissue of Rats with Heatstroke in Desert Dry and Hot Environment

[Animal Modeling]-Effect of Curcumin on Neutrophils in Blood and Tissue of Rats with Heatstroke in Desert Dry and Hot Environment

To study the effect of curcumin pretreatment on changes in blood and tissue neutrophil counts in hot swimming rats in a hot and dry desert environment?...

2021-10-27
【Animal Modeling】-The effect of bacitrin on experimental autoimmune encephalomyelitis in mice

【Animal Modeling】-The effect of bacitrin on experimental autoimmune encephalomyelitis in mice

Observe the effect of different concentrations of yellow ical glycosides on experimental autoimmune encephalomyelitis (EAE) mouse model and explore its preliminary mechanism...

2021-10-27
【Animal Modeling】-Preserving Ejection Fraction Heart Failure Animal Model

【Animal Modeling】-Preserving Ejection Fraction Heart Failure Animal Model

Heart failure is one of the leading causes of death and disability worldwide. It can be defined as abnormalities in the structure and function of the heart, which can lead to ventricular filling or impaired ejection function...

2021-10-27
【Animal Modeling】-Using CRISPR/Cas9 gene editing technology to establish a large FcγR gene knockout mouse model

【Animal Modeling】-Using CRISPR/Cas9 gene editing technology to establish a large FcγR gene knockout mouse model

Using CRISPR/Cas9 gene editing technology to knock out mouse FcγR2b, FcγR3 and FcγR4 gene clusters with a length of approximately 90 kb, laying the foundation for the construction of humanized mice with FcγR genes...

2021-10-27
【Animal Modeling】-Asthma Mouse Model

【Animal Modeling】-Asthma Mouse Model

  Observe the role of interleukin 22 (IL-22) in asthma models, and study the airway inflammation in asthma models and the regulatory effect of budesonide on IL-22...

2021-10-27
【Animal modeling】-Preclinical animal experiments show that exosomes derived from Vδ2-T cells can effectively control EBV-related tumors and induce T cell anti-tumor immune responses

【Animal modeling】-Preclinical animal experiments show that exosomes derived from Vδ2-T cells can effectively control EBV-related tumors and induce T cell anti-tumor immune responses

In a new study, researchers from the University of Hong Kong and the University of Science and Technology of China reported that exosomes derived from Vδ2-T cells (hereinafter referred to as Vδ2-T-Exos) can effectively control the Epstein-Barr virus...

2021-10-27
【Animal Modeling】-Animal Model of Bladder Stones

【Animal Modeling】-Animal Model of Bladder Stones

Breeding methods 55-60g pups are bred in a cage. Add 5% terephthalic acid (TPA) to the standard rat diet, and use the experimental diet to feed the rats for 14 consecutive days...

2021-10-27
[Animal modeling]-Changes of matrix metalloproteinase 9 and tissue inhibitor 1 in blood and tissues of hypertensive rats

[Animal modeling]-Changes of matrix metalloproteinase 9 and tissue inhibitor 1 in blood and tissues of hypertensive rats

To investigate the expression of matrix metalloproteinase 9 (MMP-9) and tissue inhibitor of metalloproteinase 1 (TIMP-1) in serum, brain and vascular tissues of rats with renal vascular hypertension (RHR), and the relationship between blood pressure...

2021-10-27
Methodological Research on Establishing Mouse Model of Learning and Memory Impairment

Methodological Research on Establishing Mouse Model of Learning and Memory Impairment

An effective method to establish a model of learning and memory impairment in mice by avoiding the dark and the Morris water maze experiment...

2021-10-27