内页大图
Home > News > News
【Animal Modeling】-The role of MicroRNA-137 and AngⅡ in cardiac remodeling in spontaneously hypertensive rats

【Animal Modeling】-The role of MicroRNA-137 and AngⅡ in cardiac remodeling in spontaneously hypertensive rats

To observe the effect of short spines on the Y chromosome sex determining region (Sox9), vascular endothelial growth factor (VEGF) and type X collagen (Col X) expression of articular chondrocytes in rabbit knee osteoarthritis (KOA). The short-term me...

2021-10-14
Progress in research on hyperinsulinemia cell model and androgen promoting pancreatic β-cell differentiation

Progress in research on hyperinsulinemia cell model and androgen promoting pancreatic β-cell differentiation

CRISPR/Cas9 pancreatic β-cell differentiation-mediated congenital hyperinsulinemia-related clinical symptoms model congenital hyperinsulinemia and ABCC8-deficient human embryonic stem cells...

2021-10-14
【Animal Modeling】-Emodin\'s Effect on Fat Browning in ApoE Knockout Mice

【Animal Modeling】-Emodin's Effect on Fat Browning in ApoE Knockout Mice

How to observe the effect of emodin on fat browning in apolipoprotein knockout (ApoE-/-) mice, and explore the mechanism of improving hyperlipidemia and other congestion?...

2021-10-14
[Disease animal model]-ligation myocardial infarction model

[Disease animal model]-ligation myocardial infarction model

Through ligation, the coronary arteries of the model animal are narrowed or occluded, and the myocardial ischemia and necrosis supplied by the coronary arteries cause myocardial infarction in the model animal...

2021-10-14
【Animal Modeling】-How to build a mouse model for vaccine research

【Animal Modeling】-How to build a mouse model for vaccine research

Scientists rely on a variety of animal models, including mice, to produce human antibodies by genetically engineering B cell receptors (a special antibody that binds to B cell membranes), thereby developing vaccines and studying human immune response...

2021-10-14
What is sperm-mediated gene transfer?

What is sperm-mediated gene transfer?

Sperm-mediated gene transfer (sperm-mediated gene transfer, SMGT) can be pre-cultured with foreign DNA through in vitro fertilization, intracellular sperm injection or vasdeferens injection, and the sperm can be combined with the foreign DNA...

2021-10-14
【Animal Modeling】-Human Rotavirus G1P[8] Infected Tree Shrew Primary Small Intestinal Epithelial Cell Model

【Animal Modeling】-Human Rotavirus G1P[8] Infected Tree Shrew Primary Small Intestinal Epithelial Cell Model

To study the proliferation characteristics of primary intestinal epithelial cells, and establish a cell model of human rotatable G1P [8] virus infection in primary intestinal epithelial cells of trees...

2021-10-14
Practice and Discussion on Biosafety of Influenza Virus Animal Laboratory

Practice and Discussion on Biosafety of Influenza Virus Animal Laboratory

Influenza virus is prone to a worldwide pandemic due to its rapid mutation, rapid spread, general susceptibility of the population, and difficulty in control....

2021-10-14
【Animal Modeling】-What is a severe combined immunodeficiency animal model?

【Animal Modeling】-What is a severe combined immunodeficiency animal model?

SCID mouse model SCID mouse is a kind of congenital T and B lymphocyte immunodeficiency animal...

2021-10-14
【Animal Modeling】-Hp-induced chronic gastric ulcer animal model

【Animal Modeling】-Hp-induced chronic gastric ulcer animal model

Regeneration method BALB/c mice, SPF grade, 5-7 weeks old, fasting for 12 hours, anesthetized and laparotomy, placed a second surgical cotton thread containing corrosive drugs on the posterior wall of the large curve of the stomach (Put 15 in the ent...

2021-10-14
【Animal Modeling】-Construction of rat COPD-OSAHS overlap syndrome model through smoking and intermittent hypoxia

【Animal Modeling】-Construction of rat COPD-OSAHS overlap syndrome model through smoking and intermittent hypoxia

  Will you establish a rat COPD-OSAHS overlap syndrome model to provide a feasible method and experimental platform for basic OS research?...

2021-10-14
【Animal modeling】-Establishment of orthotopic transplantation model of gastric cancer in nude mice

【Animal modeling】-Establishment of orthotopic transplantation model of gastric cancer in nude mice

To establish an orthotopic transplantation model of gastric cancer in nude mice...

2021-10-14
[Disease animal model]-herpes simplex virus animal model

[Disease animal model]-herpes simplex virus animal model

Herpes simplex virus (herpes simplex virus, HSV) is a DNA virus that can be cultured. It is divided into two types according to the antigenic characteristics, namely HSV1 and HSV2, which can form different animal models under different conditions, su...

2021-10-14
【Animal Modeling】-How to analyze the structure of intestinal flora of quail with hyperuricemia?

【Animal Modeling】-How to analyze the structure of intestinal flora of quail with hyperuricemia?

To explore the structural changes of the intestinal flora of quail with hyperuricemia, and to provide reference materials for studying the pathological mechanism of hyperuricemia...

2021-10-14
【Animal Modeling】-Why establish an animal model of inflammation caused by atmospheric fine particles?

【Animal Modeling】-Why establish an animal model of inflammation caused by atmospheric fine particles?

Explore the pathogenic mechanism of animal air pollution, and establish an animal model of air pollution caused by inflammation in BALB/c mice through non-invasive tracheal infusion of PM2.5 particle suspension...

2021-10-14
【Animal Modeling】-Using ultrasound-guided injection of human lung cancer cells into the left ventricle to establish a mouse model of bone metastasis

【Animal Modeling】-Using ultrasound-guided injection of human lung cancer cells into the left ventricle to establish a mouse model of bone metastasis

Establishment of a mouse model of bone metastasis of human lung cancer cells under ultrasound guidance...

2021-10-14