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【Animal model】-Rhesus monkey periapical disease model

【Animal model】-Rhesus monkey periapical disease model

The method of replication is by intraperitoneal injection of 25-50 mg/kg body weight of adult male rhesus monkeys and anesthetized with 2.5% thiopental sodium solution...

2020-08-08
How to prepare an animal model of pulpitis?

How to prepare an animal model of pulpitis?

Replication method Dilute E. coli standard endotoxin lipopolysaccharide (lipopolysaccharide, LPS) to 5 mg/ml with physiological saline, filter and sterilize for later use...

2020-08-08
How to prepare a tooth-induced pain animal model?

How to prepare a tooth-induced pain animal model?

Breeding method Use a healthy, intact cat, and anesthetize by intraperitoneal injection of sodium pentobarbital at 45 mg/kg body weight...

2020-08-08
How to prepare an animal model of gingival hyperplasia?

How to prepare an animal model of gingival hyperplasia?

Breeding method Ingested clean grade ICR male mice weighing 18-22 g for 6 to 8 weeks, and administered cyclosporin A (CsA) at a dose of 30 mg/kg body weight for 4 consecutive weeks...

2020-08-08
How to prepare oral ulcer animal model?

How to prepare oral ulcer animal model?

Breeding method SD rats weigh 150-180g and take a 6 cm long glass tube at the bottom of 3 mm diameter. The bottom of the swab is flush with the bottom of the glass tube because it contains a small swab...

2020-08-08
How to prepare an animal model of laryngeal paralysis?

How to prepare an animal model of laryngeal paralysis?

The replication method is to select an experimental dog and inject anesthetized ketamine hydrochloride intramuscularly at a dose of 30 to 50 mg/kg body weight. After placing the animal under general anesthesia, fix it on the back, make a central inci...

2020-08-08
How to prepare an animal model of acute pharyngitis?

How to prepare an animal model of acute pharyngitis?

Breeding method The rat weighs about 200 g and is kept in a clean environment. Every morning and afternoon, 15% ammonia water is sprayed on the animal’s pharynx with a slaughter spray, 3 times every 3 days...

2020-08-08
How to prepare an animal model of maxillary sinusitis?

How to prepare an animal model of maxillary sinusitis?

Replication method Anesthetize 2.5 to 3.5 kg New Zealand rabbits by intraperitoneal injection of 5 ml/kg of urethane, and fix them on the back operating table...

2020-08-08
[Animal model]-Mouse model of sinusitis

[Animal model]-Mouse model of sinusitis

Breeding method Collect type 3 capsular pneumococcus, inoculate twice to enhance the pathogenicity of mice after live bacteria inoculation, and adjust its concentration to 120×10 million CPU/ml with sterile normal saline...

2020-08-08
[Animal Model]-Rabbit Acute Sinusitis Model

[Animal Model]-Rabbit Acute Sinusitis Model

Breeding method: New Zealand rabbits weighing 2.0-2.5 kg were injected intramuscularly with ketamine hydrochloride at a weight of 50 mg/kg. After anesthesia and fixation, the midline of the rabbit\'s nose was regularly disinfected, depilated, and sus...

2020-08-08
How to prepare rat sinusitis model?

How to prepare rat sinusitis model?

Directly inject bacteria into the nasal cavity: use adult male rats weighing 200-250g and use a syringe to directly inject a certain amount of bacteria into the rat\'s sinus cavity without blocking the sinus opening after injection. According to expe...

2020-08-08
How to prepare an animal model of allergic rhinitis?

How to prepare an animal model of allergic rhinitis?

Reproduction method In adult male rats weighing 200 to 250 g, 1 mg ovalbumin (EA) and aluminum hydroxide gel are used as adjuvants, injected intraperitoneally, and 100 mg pertussis toxin is collected. Intraperitoneal injection, repeat injection after...

2020-08-08
How to prepare the animal model of basilar artery embolism?

How to prepare the animal model of basilar artery embolism?

Method of reproduction: Inject sodium pentobarbital (35 mg/kg body weight) intraperitoneally into 400-450 g pure white red-eyed guinea pigs for anesthesia, place the head on a special head frame and insert it into the trachea...

2020-08-08
How to prepare an animal model of peripheral vestibular damage?

How to prepare an animal model of peripheral vestibular damage?

  Reproduction method When the rat weighs about 200 g and the guinea pig weighs about 500 g, the external auditory canal is clean, the eardrum is intact, there is no spontaneous nystagmus, and the hearing is sharp....

2020-08-08
How to prepare an animal model of autoimmune inner ear disease?

How to prepare an animal model of autoimmune inner ear disease?

Replication method 4-week-old inbred male C57BL/6 mice and guinea pigs weighing 300 to 400 g exhibited normal ear reflex and no middle ear infection. After the guinea pig is anesthetized, the heart is perfused, the temporal bone is decapitated, all i...

2020-08-08
How to prepare an animal model of neurological deafness?

How to prepare an animal model of neurological deafness?

A variety of healthy general-grade guinea pigs, male or female, weighing 400-500 g, sensitive to ear reflexes, and otoscope examination ruled out inflammation of the outer and middle ear...

2020-08-08