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【Animal modeling】-The effect of simulated aging rat astrocyte conditioned medium on the proliferation of neural stem cells

【Animal modeling】-The effect of simulated aging rat astrocyte conditioned medium on the proliferation of neural stem cells

To establish a rat astrocyte aging model, simulate the aging of astrocytes in aged rats, and explore the effect of aging astrocyte conditioned medium on the proliferation of neural stem cells...

2022-04-27
【Animal modeling】-Determination of fecal microbial diversity of common cotton-eared marmosets based on high-throughput sequencing technology

【Animal modeling】-Determination of fecal microbial diversity of common cotton-eared marmosets based on high-throughput sequencing technology

To analyze the structure and composition of the fecal flora of the common cotton-eared marmoset by using high-throughput sequencing technology, and to lay a foundation for the further development and utilization of new experimental animals...

2022-04-27
【Animal modeling】-Directed editing of mouse MAD2L1 gene based on CRISPR/Cas9 system and analysis of its off-target effect

【Animal modeling】-Directed editing of mouse MAD2L1 gene based on CRISPR/Cas9 system and analysis of its off-target effect

To establish a method system for gene editing of the second exon of mouse MAD2L1 gene using CRISPR/Cas9 system, and to analyze the off-target effect of CRISPR/Cas9 on MAD2L1 gene editing...

2022-04-27
【Animal Modeling】-Influencing Factors in the Analysis of Serum Glucose in Rats

【Animal Modeling】-Influencing Factors in the Analysis of Serum Glucose in Rats

To investigate the influencing factors of serum glucose measurement and analysis in rats...

2022-04-27
【Animal modeling】-Regulatory effect of reed root polysaccharide on hyperlipidemia rats

【Animal modeling】-Regulatory effect of reed root polysaccharide on hyperlipidemia rats

To study the regulatory effect of reed root polysaccharide on hyperlipidemia rats...

2022-04-27
【Animal Model】-Continuous 5-day REM sleep deprivation induces delayed-onset depression-like behavior in mice

【Animal Model】-Continuous 5-day REM sleep deprivation induces delayed-onset depression-like behavior in mice

To investigate the effect of continuous long-term rapid eye movement sleep deprivation (5 d) on depression-like behavior and the level of amygdala monoamine oxidase A in C57BL/6J mice...

2022-04-27
【Animal Modeling】-Experimental Study on Lung Tissue Injury Induced by Dental Grinding Dust in Rats

【Animal Modeling】-Experimental Study on Lung Tissue Injury Induced by Dental Grinding Dust in Rats

To evaluate the effects of three kinds of dental grinding dust, cobalt chromium molybdenum metal, zirconium dioxide porcelain and polymethyl methacrylate resin, on lung tissue damage in rats...

2022-04-27
【Animal modeling】-Protective effect of ginseng coenzyme Q10 sunscreen on UV-injured mice

【Animal modeling】-Protective effect of ginseng coenzyme Q10 sunscreen on UV-injured mice

To study the protective effect of ginseng coenzyme Q10 sunscreen on UV-injured mice...

2022-04-27
【Animal Modeling】-Acupuncture improves symptoms of insomnia rats and effects on spontaneous activity by regulating GABA-Gln metabolism

【Animal Modeling】-Acupuncture improves symptoms of insomnia rats and effects on spontaneous activity by regulating GABA-Gln metabolism

To study the improvement of symptoms of acupuncture on insomnia rats and its effect on spontaneous activity, and to explore its possible mechanism...

2022-04-27
【Animal modeling】-The protective effect of mild hypothermia on radiation-induced lung injury in rats

【Animal modeling】-The protective effect of mild hypothermia on radiation-induced lung injury in rats

To investigate the protective effect of mild hypothermia on radiation-induced lung injury, and to compare the protective effect with the commonly used clinical anti-radiation drug amifostine...

2022-04-27
【Animal modeling】-Cloning and molecular characterization of the full-length coding sequence of tree shrew BACE1

【Animal modeling】-Cloning and molecular characterization of the full-length coding sequence of tree shrew BACE1

To obtain the full-length coding sequence of the tree shrew β-amyloid precursor protein cleaving enzyme BACE1 and analyze its molecular characteristics, so as to provide a basis for the research on the mechanism of AD disease...

2022-04-27
【Animal modeling】-Effect of camel milk on glucose and lipid metabolism and PPAR-γ, TNF-α mRNA in type 2 diabetic rats

【Animal modeling】-Effect of camel milk on glucose and lipid metabolism and PPAR-γ, TNF-α mRNA in type 2 diabetic rats

To study the effect of camel milk (CM) on body weight, blood glucose, blood lipid, insulin, PPARγ and TNF-α gene expression in type 2 diabetic rats...

2022-04-27
【Animal Modeling】-Feasibility of Transjugular Liver Biopsy in Miniature Pigs

【Animal Modeling】-Feasibility of Transjugular Liver Biopsy in Miniature Pigs

To investigate the feasibility and safety of transjugular liver biopsy (TJLB) using the LABS 200 intrahepatic biopsy needle set from Cook Company...

2022-04-27
【Animal Modeling】-An overview of experimental methods for depressive behavior in rats and mice

【Animal Modeling】-An overview of experimental methods for depressive behavior in rats and mice

Depression is a common mental disease with high prevalence, high disability rate, and high recurrence rate, and its pathogenesis is complex....

2022-04-27
【Animal modeling】-The expression changes of DR5 and DcR2 in ovarian granulosa cells of rats with polycystic ovary syndrome

【Animal modeling】-The expression changes of DR5 and DcR2 in ovarian granulosa cells of rats with polycystic ovary syndrome

To observe the expression changes of DR5 and DcR2 in ovarian granulosa cells of rats with polycystic ovary syndrome, and to explore the possible mechanism of follicular developmental disorders in rats with PCOS...

2022-04-27
【Animal modeling】-Analysis of echocardiographic examination of Bama miniature pigs under compound anesthesia with Lu Mianning

【Animal modeling】-Analysis of echocardiographic examination of Bama miniature pigs under compound anesthesia with Lu Mianning

To observe the general anesthesia effect of Lu Mianning compound anesthesia on miniature pigs, and to emphasize the safety awareness of general anesthesia. Echocardiography was used to study the main functions and structures of normal minipig hearts...

2022-04-27