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![[Animal Modeling]-Periodontitis model formed by the combination of systemic factors and local factors](/./uploads/images/default/default.png)
Replication method Inject pentobarbital sodium (30 mg/kg body weight) intraperitoneally into rats of 180 to 220 g to destroy the attachment of the gum epithelium after anesthesia, and then destroy the neck of the tooth (collected by the tooth)...
2022-02-04The breeding method uses Keyes 2000 mixed feed (fructose 56%, decomposable milk powder 28%, wheat flour 6%, yeast 4%, alfalfa meal 3%, animal liver meal 1%, salt 2%) and a small amount of vegetables in adult golden hamsters After 6 weeks of micro-his...
2022-02-04A 3.0 silk thread was used to ligate the gingival margin of the neck of the ferret test tooth. After 14 days, the animal’s gums became red and swollen and bleed easily when palpated...
2022-02-04Breeding method Healthy rhesus macaques (Rhesus macaques) and cynomolgus monkeys (M.fascicularis) between 3 and 6 years old are injected intramuscularly with 0.15 ml/kg body weight for fast sleep, and then re-anaesthetized in the nose and trachea...
2022-02-04![[Animal modeling]-Thioacetamide (TAA) induced liver failure model](/./uploads/images/20200807/be69618d7ef01.jpg)
Replication method Adult rats are injected intraperitoneally with thioacetamide (TAA) 250-350 mg/kg body weight, or subcutaneously injected 600 mg/kg body weight, or oral gavage 300-400 mg/kg body weight, each with the original 24 hours after dose...
2022-02-04
The occurrence of infection in laboratory animal facilities is the result of a combination of many factors. In addition to human and social factors, the characteristics of pathogenic microorganisms, the sensitivity of the human body to pathogens, env...
2022-02-04A large number of toxic chemicals are stored in the workplace. As with emergency procedures in case of poisoning, it is important to understand the toxicity of chemical substances to the environment and self-protection equipment...
2022-02-04The main way for bacteria to enter the prostate is inflammation, edema or obstruction of the lower urethra, which will increase the pressure of the urethra and cause urine containing bacteria to return to the ducts and acinars of the prostate. Altern...
2022-02-03The incidence of prostate cancer model caused by the combination of chemical carcinogen DMAB and long-acting testosterone propionate (TP) is high. The cancer originates from the dorsal and middle lobe, and it has homology with cancer....
2022-02-03Removal of the right kidney and clamping of the left renal artery can cause renal ischemic mitochondrial dysfunction and produce large amounts of hypoxanthine. In the hypoxic state, hypoxanthine cannot be metabolized into xanthine and accumulate in l...
2022-02-03The chemical carcinogens are directly applied to the tissues through local embedding and other methods. These carcinogens act on the surface epithelium of the ovary and cause cell transformation. At the same time, it is also possible to change the go...
2022-02-03The gene knockout mouse model uses transgenic technology to artificially knock out related genes that inhibit tumor occurrence, development and metastasis, and eliminates homologous recombination and Cre/loxP-induced conditional knockout system metho...
2022-02-03Renal vein ligation can lead to renal ischemia, renal tubular injury, ischemic atrophy and renal tubular loss, renal interstitial hyperplasia and tubular interstitial fibrosis (TIF) [Modeling method: weight 200-250 grams, weight percentage Anesthetiz...
2022-02-03Acute ischemia delays the conduction of impulse in the atrial ischemic area, making reentry easy to form, leading to the occurrence of atrial fibrillation...
2022-02-03The animal model of chronic myocardial ischemia is the gradual occlusion or stenosis of coronary arteries, which gradually causes myocardial ischemia to form ischemic cardiomyopathy. It is more consistent with the clinical pathophysiological process,...
2022-02-03Since Rygaard and Povlsen first successfully transplanted excised human cancer tissue specimens into nude mice in 1969, the transplanted tumor models have been widely used in tumor growth and metastasis research. .. Common methods for establishing CR...
2022-02-03