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[Animal Modeling]-Mouse experiments reveal that obesity can also make the sense of taste dull?

[Animal Modeling]-Mouse experiments reveal that obesity can also make the sense of taste dull?

Previous studies have shown that weight gain will reduce the body’s sensitivity to food taste, and the sense of smell can be restored with weight loss...

2022-02-04
【Animal Modeling】-Construction and research of eukaryotic expression vector of full-length and mature IL-37b

【Animal Modeling】-Construction and research of eukaryotic expression vector of full-length and mature IL-37b

Construct the eukaryotic expression vector pEGFPN1/IL-37b of full-length mature IL-37b, and detect its expression in RAW264.7 cells...

2022-02-04
【Animal Modeling】-Mice experiments revealed that excessive diet during lactation will affect the health of children

【Animal Modeling】-Mice experiments revealed that excessive diet during lactation will affect the health of children

A new study on mice shows that breastfeeding women who eat too much may increase their risk of obesity and puberty in the future, which can lead to diabetes and other infertility...

2022-02-04
[Animal Modeling] The effect of botulinum toxin type A heavy chain intervention on the expression of growth-related proteins after spinal cord injury in rats

[Animal Modeling] The effect of botulinum toxin type A heavy chain intervention on the expression of growth-related proteins after spinal cord injury in rats

To investigate the effect of artificial recombinant botulinum toxin type A heavy chain (BoNT/A heavy chain) on the expression of local growth-related proteins in rat spinal cord injury and promote neurite regeneration. It provides evidence to clarify...

2022-02-04
【Animal modeling】-Selective cathepsin K inhibitor MIV-711 reduces joint pathology in animal models of osteoarthritis

【Animal modeling】-Selective cathepsin K inhibitor MIV-711 reduces joint pathology in animal models of osteoarthritis

Osteoarthritis (OA) is a common musculoskeletal disease characterized by damage to the joint structure, leading to symptoms such as joint stiffness and pain...

2022-02-04
【Animal Modeling】-Xueshuantong Capsule\\

【Animal Modeling】-Xueshuantong Capsule

How to study the protective effect of Panax Notoginseng Saponins (PNS) and its monomer Rg1? b1 affects the tight junction damage of vascular endothelium caused by oxygen glucose deprivation (OGD)...

2022-02-04
【Animal Modeling】-The effect of high-fat feed feeding time on type 2 diabetic nephropathy rat model

【Animal Modeling】-The effect of high-fat feed feeding time on type 2 diabetic nephropathy rat model

To explore the effect of high-fat diet feeding time on blood glucose, insulin resistance index (HOMA-IR) and urinary albumin excretion rate (UAER) in type 2 diabetic nephropathy (DN) rats...

2022-02-04
【Animal modeling】-Bleomycin-induced pulmonary fibrosis model

【Animal modeling】-Bleomycin-induced pulmonary fibrosis model

Bleomycin (bleomycin) is a polypeptide anti-tumor drug, and its mechanism of causing pulmonary interstitial fibrosis is mainly through the action of reactive oxygen species. In the early stage of lung injury caused by bleomycin, that is, the alveolit...

2022-02-04
【Animal Modeling】-The effect of TRPV4 receptor on the renal damage induced by angiotensin II in mice

【Animal Modeling】-The effect of TRPV4 receptor on the renal damage induced by angiotensin II in mice

Use transient receptor potential vanilloid type 4 (TRPV4) gene knockout (TRPV4-/-) mice to study the role of TRPV4 receptor in kidney damage caused by angiotensin II (angiotensin II, Ang II) effect...

2022-02-04
How to prepare animal model of blood stasis syndrome?

How to prepare animal model of blood stasis syndrome?

Congestion syndrome (blood loss syndrome) is caused by qi deficiency, qi stagnation, hot toxins, cold blood, etc., blocking blood flow and accumulating in the meridians or organs...

2022-02-04
[Animal Modeling] Japan has developed a new bioluminescence system that can observe brain activity in living animals

[Animal Modeling] Japan has developed a new bioluminescence system that can observe brain activity in living animals

Japan Institute of Physical Chemistry has developed a new type of bioluminescence system that can observe the brain activity of living animals...

2022-02-04
What are the design principles of animal models?

What are the design principles of animal models?

In the design of biomedical scientific research, the question of how to build animal models is usually considered, because there are currently no or should not be conducted on patients to clarify the mechanism and efficacy of many experiments. Will b...

2022-02-04
[Animal Modeling]-How to model acute renal failure?

[Animal Modeling]-How to model acute renal failure?

Acute renal failure model of dog renal artery contraction: Take a 10-20 kg male dog, anesthetize with pentobarbital sodium 30 mg/kg, and expose the left renal artery surgically. Clamp it for 1 hour, then relax, reperfuse, and collect urine from the u...

2022-02-04
[Animal Modeling]-Gender Wars in Genes Both male and female fruit flies need a certain gene, but they are used for different purposes-how can such genes evolve?

[Animal Modeling]-Gender Wars in Genes Both male and female fruit flies need a certain gene, but they are used for different purposes-how can such genes evolve?

As we all know, when a species needs to change to adapt to its specific needs, evolution can be of great help...

2022-02-04
【Animal Modeling】-Scientists try new methods of stem cell tooth regeneration in experimental dogs

【Animal Modeling】-Scientists try new methods of stem cell tooth regeneration in experimental dogs

Researchers in the laboratory have discovered a new method of using the regeneration ability of stem cells in the laboratory to regenerate dog teeth in the open laboratory of \\\"Gene and Stem Cell Technology\\\" of Kazan Federal University...

2022-02-04
[Animal Modeling]-Periodontitis model formed by oral inoculation of bacteria

[Animal Modeling]-Periodontitis model formed by oral inoculation of bacteria

Replication method Oral Porphyromonas gingivalis to periodontitis model animals. 4 days before the experiment, an adult rat weighing 250 g was injected intramuscularly with kanamycin or ampicillin at a dose of 20 mg per head...

2022-02-04
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