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Chronic bronchitis (chronic bronchitis) refers to chronic non-specific inflammation of the trachea, bronchial mucosa and surrounding tissues caused by infectious or non-infectious factors. The pathological features of chronic bronchitis are bronchial...
2022-02-03Bleomycin is a peptide antitumor drug. The mechanism of pulmonary fibrosis is mainly due to the action of reactive oxygen species. In the early stage of bleomycin lung injury, that is, the alveolitis stage, a large amount of oxygen free radicals are...
2022-02-03Large doses of adrenaline directly stimulate beta receptors, increase cardiac autonomy, conductivity, hypersensitivity, etc., and cause arrhythmia (ventricular premature beats, ventricular tachycardia, and even ventricular fibrillation). Even movemen...
2022-02-03When an allergen (usually used ovalbumin) is injected into a guinea pig, its soluble antigen component will stimulate the body to produce IgE, which leads to an allergic state. When the animal comes into contact with the antigen again, the antigen-an...
2022-02-03By ligating the coronary arteries of the model animals, the coronary arteries become narrowed or occluded, and the myocardium supplied from the coronary arteries is ischemia or necrosis, thereby causing myocardial infarction in the model animals...
2022-02-03Myocardial ischemia is a state in which the supply of the heart decreases when the blood perfusion of the heart is reduced, the energy metabolism of the myocardium is abnormal and normal heart function cannot be maintained...
2022-02-03Studies have shown that the vagus nervous system may be involved in the formation and maintenance of atrial fibrillation, especially it is closely related to atrial fibrillation caused by pulmonary veins...
2022-02-03The rapid atrial pacing atrial fibrillation model is currently the most studied and most widely used animal model of chronic atrial fibrillation. This mechanism is related to electrical and structural remodeling caused by rapid atrial pacing...
2022-02-03Mice (Musmusculus) Mice commonly used in medical experiments belong to mammals, rodents, Murriidae, rats and Mus musculus species. It is small in size, easy to capture, easy to operate, short growth period, fast maturity, and strong fecundity. Gentle...
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2022-02-03The mediastinal nerve is a mixed nerve plexus, including the parasympathetic ganglion, sympathetic nerves and afferent nerves of the limbs...
2022-02-03The \\\\\\\"syndrome\\\\\\\" model of traditional Chinese medicine is to reproduce different clinical manifestations of animals and reveal different syndrome types...
2022-02-03Reproduction method: Guinea pigs are often used to reproduce acute allergic bronchospasm. Use normal saline to make 1:10 egg white solution as sensitizing antigen...
2022-02-03The general method is to inject the serum of hepatitis B patients to replicate the hepatitis B model. Most laboratory animals are not affected by the hepatitis A virus. There are reports of human hepatitis A in red-faced macaques, rhesus monkeys, hum...
2022-02-03Methods to replicate myocardial ischemia and myocardial infarction models in animals include coronary artery ligation and left circumflex coronary artery ligation, but most of the left anterior descending artery ligation...
2022-02-03Use genetic engineering and other experimental techniques to intentionally modify the animal genome. The modified genes are stably inherited by offspring animals, and various mouse models have been established. One type of model is mainly for animal...
2022-02-03