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【Animal Modeling】-How to use CRISPR-Cas9 to construct a new animal model of a lethal virus?

【Animal Modeling】-How to use CRISPR-Cas9 to construct a new animal model of a lethal virus?

Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a new type of highly pathogenic coronavirus that has emerged in recent years...

2022-01-22
[Animal modeling]-The protective effect of Nrf2 antioxidant pathway in the acute liver injury induced by CCl4 in a mouse model of hyperuricemia renal damage

[Animal modeling]-The protective effect of Nrf2 antioxidant pathway in the acute liver injury induced by CCl4 in a mouse model of hyperuricemia renal damage

To study the protective effect of Nrf2 oxidative damage pathway in CCl4 induced acute liver injury in rats...

2022-01-22
【Animal Modeling】-Cough variant asthma model in rats

【Animal Modeling】-Cough variant asthma model in rats

Use Ovalbumin Brown (OVA) to establish a simple and feasible animal model of cough and asthma to sensitize Norwegian (BN) rats...

2022-01-22
【Animal modeling】-Escherichia coli induced chronic fallopian tube inflammation model in rabbits

【Animal modeling】-Escherichia coli induced chronic fallopian tube inflammation model in rabbits

Establishment of a New Zealand Rabbit Fallopian Tube Chronic Inflammation Model Using Escherichia coli...

2022-01-22
[Animal Modeling]-Muscle Atrophy Model

[Animal Modeling]-Muscle Atrophy Model

Establish an animal model of cynomolgus muscle atrophy, and use the method of restricting lower limb movement to establish a model evaluation method?...

2022-01-22
【Animal Modeling】-The protective effect of acupuncture combined with Danhong injection on cerebral ischemia-reperfusion injury in rats

【Animal Modeling】-The protective effect of acupuncture combined with Danhong injection on cerebral ischemia-reperfusion injury in rats

To explore the protective effect of acupuncture combined with Danhong injection on cerebral ischemia-reperfusion injury in rats...

2022-01-22
【Animal Modeling】-High-fat diet combined with STZ induces gestational diabetes mouse model

【Animal Modeling】-High-fat diet combined with STZ induces gestational diabetes mouse model

Explore the method of establishing a stable and reliable mouse model of insulin resistance during pregnancy...

2022-01-21
[Animal Modeling]-Breast Cancer Experimental Animal Model

[Animal Modeling]-Breast Cancer Experimental Animal Model

Breast cancer is the second most common cancer in the world...

2022-01-21
【Animal Modeling】-Comparison of Different Methods of Inducing THP-1 Cell Differentiation

【Animal Modeling】-Comparison of Different Methods of Inducing THP-1 Cell Differentiation

Optimize different methods to stimulate the directional differentiation of THP-1 cells into M1, M2 macrophages and DC cells, laying the foundation for the study of three in vitro cell models of M1, M2 and DC...

2022-01-21
【Animal modeling】The effect of -1α,25(OH)2D3 on the expression of lubricin in rat articular chondrocytes

【Animal modeling】The effect of -1α,25(OH)2D3 on the expression of lubricin in rat articular chondrocytes

To investigate the effect of 1α,25(OH)2D3 on the synthesis and secretion of lubricin in chondrocytes at the cellular level...

2022-01-21
【Animal Modeling】-A single intraosseous injection of simvastatin promotes normalization of tumor blood vessels in mouse breast cancer

【Animal Modeling】-A single intraosseous injection of simvastatin promotes normalization of tumor blood vessels in mouse breast cancer

To study the effect of a single intraosseous injection of simvastatin on the vascular structure and function of mouse breast cancer tumors...

2022-01-21
【Animal modeling】-Flow cytometry analysis of the phenotypic characteristics of PMA-induced THP-1 differentiation into macrophages

【Animal modeling】-Flow cytometry analysis of the phenotypic characteristics of PMA-induced THP-1 differentiation into macrophages

To clarify the differentiation of macrophages derived from THP-1 cells induced by PMA alone by flow cytometry...

2022-01-21
【Animal Modeling】-Effect of Mac-1 gene deletion on the growth of melanoma

【Animal Modeling】-Effect of Mac-1 gene deletion on the growth of melanoma

To investigate the effect of Mac-1 deletion on melanoma tumor growth...

2022-01-21
【Animal modeling】-Effect of miR-424 on migration and invasion of non-small cell lung cancer cell line A549

【Animal modeling】-Effect of miR-424 on migration and invasion of non-small cell lung cancer cell line A549

To investigate the effect of miR-424 on the migration and invasion of non-small cell lung cancer cell line A549...

2022-01-21
【Animal modeling】-Expression and regulation of PCOS susceptibility gene Hmga2 in mouse uterine decidualization

【Animal modeling】-Expression and regulation of PCOS susceptibility gene Hmga2 in mouse uterine decidualization

To study the expression and regulation of PCOS susceptibility gene Hmga2 in endometrial receptivity and decidualization...

2022-01-21
【Animal Modeling】-A single intraosseous injection of simvastatin promotes normalization of tumor blood vessels in mouse breast cancer

【Animal Modeling】-A single intraosseous injection of simvastatin promotes normalization of tumor blood vessels in mouse breast cancer

To study the effect of a single intraosseous injection of simvastatin on the vascular structure and function of mouse breast cancer tumors...

2022-01-19