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【Animal Modeling】-MPTP-induced C57BL/6 mouse Parkinson\\

【Animal Modeling】-MPTP-induced C57BL/6 mouse Parkinson

Establish a stable 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced C57BL/6 mouse Parkinson\\\'s model and evaluate the model\\\'s behavior...

2021-09-23
【Animal Modeling】-Study on the differential expression of lysozyme 1 in the incubation and resting blastocysts before and after superovulation in mice

【Animal Modeling】-Study on the differential expression of lysozyme 1 in the incubation and resting blastocysts before and after superovulation in mice

To study the distribution and expression of lysozyme 1 gene in mouse hatching blastocysts and dormant embryos before and after superovulation, and explore new regulatory mechanisms during animal embryo implantation...

2021-09-23
【Animal Modeling】-The Intervention Effect of Valsartan on High Glucose Induced Viability of Rat Glomerular Mesangial Cells

【Animal Modeling】-The Intervention Effect of Valsartan on High Glucose Induced Viability of Rat Glomerular Mesangial Cells

To investigate the effect and mechanism of valsartan on the proliferation and apoptosis of rat kidney cells induced by high glucose...

2021-09-23
【Animal Modeling】-Zhenqi Fuzheng Granules inhibit angiogenesis in liver cancer model rats through miR-200c/ZEB pathway

【Animal Modeling】-Zhenqi Fuzheng Granules inhibit angiogenesis in liver cancer model rats through miR-200c/ZEB pathway

To explore the inhibitory effect of Zhenqi Fuzheng Granules on angiogenesis in liver cancer model rats and its possible mechanism...

2021-09-19
【Animal Modeling】-What is the quail gout model?

【Animal Modeling】-What is the quail gout model?

Preliminarily study how to induce quail gout by simulating clinical high-protein and high-calcium diet, establish a quail gout model, study and prevent the etiology of gout, and provide evidence for drug screening?...

2021-09-19
How tuberculosis bacillus is transmitted from animals to humans

How tuberculosis bacillus is transmitted from animals to humans

Tuberculosis (tuberculosis) is one of the most persistent and deadly infectious diseases in the world. Therefore, between 1 and 2 million people die every year...

2021-09-19
【Animal Modeling】-Experimental autoimmune myasthenia gravis mouse model

【Animal Modeling】-Experimental autoimmune myasthenia gravis mouse model

How to establish an experimental autoimmune myasthenia gravis animal model that meets the international preclinical experimental standards?...

2021-09-19
【Animal Modeling】-α-Mangostin on the immune function of immunosuppressive mice

【Animal Modeling】-α-Mangostin on the immune function of immunosuppressive mice

To explore the effect of α-mangostin on the immune function of cyclophosphamide-induced mouse immunosuppressive model, and provide experimental basis for subsequent mechanism research and the development of new drugs that increase immune function...

2021-09-19
【Animal Modeling】-an animal model of transformational preclinical pharmacological diseases

【Animal Modeling】-an animal model of transformational preclinical pharmacological diseases

The pathology of the eye is usually divided into different categories according to the affected area: ocular surface diseases, anterior and posterior diseases. Cataracts, age-related macular degeneration (AMD), glaucoma, presbyopia, dry eye (DED), ey...

2021-09-19
Therapeutic effect of rapamycin on primary sclerosing cholangitis induced by DDC in mice

Therapeutic effect of rapamycin on primary sclerosing cholangitis induced by DDC in mice

To explore the therapeutic effect of rapamycin on primary sclerosing cholangitis (PSC) in mice induced by 3,5-diethoxycarbonyl 1,4-dihydrocollidine (DDC), and explore its potential mechanism of action...

2021-09-19
Using genetic diversity mouse resources to screen CA16 pathogenicity-related genes

Using genetic diversity mouse resources to screen CA16 pathogenicity-related genes

Coxsackievirus A16 (Coxsackievirus A16, CA16) is one of the main pathogens of hand, foot and mouth disease, and its pathogenic mechanism is still unclear...

2021-09-19
【Animal Modeling】-Experimental Study on the Model of Focal Cerebral Ischemia in Balb/c Mice Made by Electrocoagulation

【Animal Modeling】-Experimental Study on the Model of Focal Cerebral Ischemia in Balb/c Mice Made by Electrocoagulation

Observe the feasibility of electrocoagulation on the middle cerebral artery in mice, and the feasibility of occluding the middle cerebral artery to establish a model of cerebral ischemia in mice...

2021-09-19
[Animal Modeling]-Construction of a Systemic Model of Parkinson\\

[Animal Modeling]-Construction of a Systemic Model of Parkinson

By applying behavioral and molecular imaging methods to dynamically evaluate the clinical characteristics of the cynomolgus monkey Parkinson\\\'s disease systemic model, providing stable and effective PD for preclinical studies of drugs, stem cells a...

2021-09-19
【Animal Modeling】-Levofloxacin-resistant mouse model

【Animal Modeling】-Levofloxacin-resistant mouse model

To detect the effect of low-concentration levofloxacin on the pneumonia model of Pseudomonas aeruginosa (PA) infection in mice, and to explore the method of levofloxacin resistance?...

2021-09-19
【Animal Modeling】-Aβ1-40 lateral ventricle injection to simulate Alzheimer\\

【Animal Modeling】-Aβ1-40 lateral ventricle injection to simulate Alzheimer

To analyze the brain imaging characteristics of tree shrews in Alzheimer\\\'s disease model...

2021-09-19
[Animal Modeling]-Application of Nile Red Tracer Nanoformulation in In vivo Imaging of Tumor-bearing Nude Mice

[Animal Modeling]-Application of Nile Red Tracer Nanoformulation in In vivo Imaging of Tumor-bearing Nude Mice

It is planned to wrap Nile Red in nano preparations and use its fluorescence characteristics to investigate the tumor targeting and tissue distribution of nano preparations in tumor-bearing mice...

2021-09-19
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