【Animal modeling】-animal model of lung adenocarcinoma brain metastasis

Use luc+-PC-9 human lung adenocarcinoma cells that stably express luciferase to establish a lung cancer brain metastasis animal model, compare bioluminescence imaging and 18F-FDG (18F-fluorodeoxyglucose, 18F-fluorodeoxyglucose) SPECT/CT in lung cance...

2021-09-16

[Animal modeling]-Resveratrol's inhibitory effect on rat blood hypercoagulability and its relationship with the expression of NF-κB

To study the effect of resveratrol on the formation of blood hypercoagulability in rats and its relationship with the expression of NF-κB...

2021-09-15

【Animal Modeling】-The effect of high-fat diet on insulin resistance and the expression of liver insulin receptor substrates 1 and 2 in Tibet miniature pigs

Discuss the effect of high-fat diet on the expression of insulin resistance (IR) and hepatic insulin receptor substrates (IRS) 1 and 2 in Tibet miniature pigs...

2021-09-15

【Animal Modeling】-The Protective Effect and Mechanism of Pine Bark Extract on Cerebral Ischemia-Reperfusion Injury in Mice

Discuss the neurotherapeutic effect and mechanism of IL-6/STAT3/miR-21 in pine bark extract on cerebral ischemia-reperfusion injury in mice...

2021-09-15

【Animal Modeling】-High-salt diet triggers cognitive deficits in the brains of mice

The \\\"heavy taste\\\" diet has become a daily choice for most people, but a study in mice published by American scientists on the 14th in the British journal \\\"Nature Neuroscience\\\" found that a high-salt diet can affect the...

2021-09-15

【Animal Modeling】-Based on the OPG-RANK-RANKL system to study the effects of different dietary calcium levels on bone metabolism in growing WHBE rabbits

To apply the OPG-RANK-RANKL ligand (OPG-RANK-RANKL) system to discuss the effects of different levels of dietary calcium on bone metabolism in growing WHBE rabbits...

2021-09-15

【Animal Modeling】-The effect of histamine on the desire for movement and the ability of spatial memory in depression rats

Taking SD rats as the research object, explore the effect of histamine on the neurons in the hippocampal C1 area and the effect on the behavior of depression rats?...

2021-09-15

【Animal Modeling】-The effects of different local intervention temperatures on the endoplasmic reticulum stress and cell apoptosis in rats with pressure ulcers

To compare the effects of different local intervention temperatures on endoplasmic reticulum stress (ERS) and cell apoptosis in rats with pressure ulcers in order to provide experimental evidence for clinical prevention and treatment of pressure ulce...

2021-09-15

【Animal Modeling】-The neuroprotective effect of erythropoietin in a rat model of hypoxic-ischemic encephalopathy

To create a hypoxic-ischemic encephalopathy (hyPoxic?ischemic encePhaloPathy, HIE) model in reborn rats, to study the brain maintenance effect of recombinant human erythropoietin (EPO) and the diversity of HIE intestinal flora in reborn rats Changes,...

2021-09-15

【Animal Modeling】-Tempol's Effect on NF-κB Signaling Pathway in Rats with Cardiac Hypertrophy

To discuss the effect of 2, 2, 6, 6-tetramethyl-4-piperidinol (temPol) on NF-κB signaling pathway in rat cardiac hypertrophy?...

2021-09-15

【Animal Modeling】-Analysis of the effect of rat portal hypertension on serum endotoxin and intestinal mucosa

To study the effect of simple portal hypertension on serum endotoxin and intestinal mucosa in rats?...

2021-09-15

【Animal Modeling】-Cysteinyl leukotriene receptor antagonist reduces the global cerebral ischemia-reperfusion injury of Mongolian gerbils by down-regulating autophagy

Discuss the protective effect and mechanism of cysteinyl leukotriene receptor antagonists (Plukast, HAMI 3379) on global cerebral ischemia-reperfusion injury in Mongolian gerbils...

2021-09-15

【Animal Modeling】-Inhibition of Peripheral Neuron PAR2-PKA/PKCε Pathway on Pain Threshold of Pain Transformation Model Rats

Discuss the role of peripheral neuronal protease activated receptor 2-protein kinase A/protein kinase Cε (PAR2-PKA/PKCε) pathway in the transformation of pain, and look for possible plans for simultaneous intervention in acute pain and chronic pain...

2021-09-15

【Animal modeling】-Comparison of dopamine content in the lateral geniculate body of guinea pigs with flash-induced myopia and form-deprivation myopia

Observe the changes of dopamine (DA) content in the lateral geniculate body in guinea pig stroboscopic-induced myopia and form-deprivation myopia models, and stop the comparative analysis, and discuss the central pathogenesis of different myopia mode...

2021-09-15

【Animal Modeling】-The effect of vitamin D deficiency on the pathogenesis of spontaneous diabetic rats

To investigate the effect of vitamin D (VD) deficiency on the pathogenesis of spontaneous diabetic rats...

2021-09-15

【Animal Modeling】-What are the negative effects of Busulfan on the function of hematopoietic stem cells in mice?

To detect the effects of different administration methods on the function of hematopoietic stem cells in mice...

2021-09-15