【Animal Modeling】-High-fat and high-purine diet combined with potassium oxazinate induces quail glucose and lipid metabolism disorder and its complications

Establish a practical animal model of chronic metabolic disease to explore the relationship between hyperuricemia and glucose and lipid metabolism and its pathological damage mechanism...

2021-07-12

[Animal Modeling] The role of -ripply1 in the dorsal-ventral development of early zebrafish embryos

To investigate the role of ripply1 gene in the early development of dorsoventral axis in zebrafish...

2021-07-08

【Animal Modeling】-Genetic Screening of Mutants with Developmental Defects in Zebrafish Digestive Organs

Positive genetic screening of zebrafish liver, intestine, and gallbladder dysplasia mutants...

2021-07-08

【Animal Modeling】-Application of rodent tracheal intubation under direct vision guided by optical fiber

Establish a simple rodent intubation method, and use this method to establish various animal models that require tracheal intubation...

2021-07-08

[Animal Modeling]-Isolation, Culture and Identification of Bacteria from Tree Shrew Feces

Understand the diversity of the fecal flora of artificially breeding tree shrews, and provide a basis for the normal breeding of tree shrews and the standardization of microbial quality control...

2021-07-08

【Animal Modeling】-The protective effect of Danggui Buxue Decoction on radiation-damaged mice

Observe the protective effect of Danggui Buxue Decoction on mice irradiated with 60C0-γ rays...

2021-07-08

【Animal Modeling】-The effect of natural spring water on SOD and MDA content in aged mice

Explore the effect of natural hot spring water on lipid peroxidation in old mice...

2021-07-08

【Animal Modeling】-Comparison of the four test results of SD rats with two different reagents

Obtain the test results of four blood coagulation tests (PT, APTT, TT, FIB) in SD rats and human (PT, APTT, TT, FIB) experimental animals, and the results of blood cell aggregation tests of two different brands in Japan and Japan...

2021-07-08

Animal trials of gene therapy for hemophilia succeeded

Hemophilia is a disease caused by hereditary coagulation dysfunction. It is characterized by the body\'s inability to produce coagulation factors or insufficient production of coagulation factors, which leads to long clotting time, bleeding, and it b...

2021-07-07

Effect of deletion of ubiquitin carboxyl-terminal hydrolase 1 gene on the development of female mouse reproductive system

To study the effect of ubiquitin C-terminal hydrolase L1UCH-L1 gene deletion on the reproductive system of female mice...

2021-07-07

The lipid-lowering effect of citrus polymethoxyflavonoid biscuits on hyperlipidemia mice

This study was the first to evaluate the lipid-lowering effect of adding citrus polymethoxyflavonoid powder in biscuits in a mouse model of hyperlipidemia by measuring lipid metabolism experimental indicators, aiming to provide a new type of function...

2021-07-07

Intervention effect of valsartan on high glucose-induced injury of rat glomerular mesangial cells activity

To investigate the effect and mechanism of valsartan on the proliferation and apoptosis of rat kidney cells induced by high glucose...

2021-07-07

The protective effect and mechanism of estrogen on oxidative stress injury of mouse osteoblast MC3T3-E1

To explore the protective effect and mechanism of estrogen on oxidative stress injury of mouse osteoblast MC3T3-E1...

2021-07-07

Effect of human umbilical cord mesenchymal stem cells on autophagy level in hippocampus of naturally aging rats

In this study, human umbilical cord mesenchymal stem cell transplantation can improve the decline of learning, memory and cognitive ability in naturally aging rats by regulating the level of autophagy. The research is feasible...

2021-07-07

Based on Rho/Rho-kinase signaling pathway to explore the effect of propofol on reducing cerebral ischemia-reperfusion injury in rats

Based on the Rho/Rho-kinase signaling pathway to study the effect of propofol on reducing cerebral ischemia-reperfusion injury in rats...

2021-07-07

Animal experiment study of two different types of left atrial appendage occluder

To evaluate the feasibility and safety of two different left atrial appendage occluders (single-disc cylindrical type and double-disc split type) for blocking the left atrial appendage of the target animal...

2021-07-07