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【Animal Modeling】-Lentivirus-mediated ACE2 overexpression affects the albumin expression and migration ability of rat hepatocytes induced by angiotensin Ⅱ

【Animal Modeling】-Lentivirus-mediated ACE2 overexpression affects the albumin expression and migration ability of rat hepatocytes induced by angiotensin Ⅱ

To explore the inhibitory effect of angiotensin converting enzyme 2 (ACE2) on the over-regulation of hepatocyte albumin expression induced by angiotensin II (Ang II) and enhance cell migration...

2021-01-25
Effect of alcohol exposure during pregnancy on basic rhythmic respiratory discharge in medulla oblongata of newborn rats

Effect of alcohol exposure during pregnancy on basic rhythmic respiratory discharge in medulla oblongata of newborn rats

To explore the effect of drinking during pregnancy on the basic rhythmic respiratory discharge activity (RRDA) of the medulla oblongata slices in the offspring of newborn rats...

2021-01-25
High-intensity focused ultrasound inhibits the metastasis of mouse melanoma cells B16-F10 in vivo

High-intensity focused ultrasound inhibits the metastasis of mouse melanoma cells B16-F10 in vivo

To explore the effect of high intensity focused ultrasound (HIFU) treatment on the metastasis of melanoma cells in the mouse model of melanoma...

2021-01-22
Schistosoma japonicum recombinant Bb (pGEX-Sj32) vaccine induces the dynamic changes of BALB/c mouse splenocyte proliferation, subpopulation and cytokine

Schistosoma japonicum recombinant Bb (pGEX-Sj32) vaccine induces the dynamic changes of BALB/c mouse splenocyte proliferation, subpopulation and cytokine

Observe the dynamic changes of the immune response of mouse spleen cells induced by the recombinant Bb vaccine of Schistosoma japonicum, and study its immune mechanism...

2021-01-22
【Animal Modeling】-The role of KA1 subreceptors in the death of hippocampal neurons caused by endoplasmic reticulum stress

【Animal Modeling】-The role of KA1 subreceptors in the death of hippocampal neurons caused by endoplasmic reticulum stress

To explore the role of up-regulation of KA1 receptor in the death of hippocampal neurons caused by endoplasmic reticulum stress...

2021-01-22
【Animal Modeling】-Effect of electroacupuncture on the expression of ankle joint myeloid cells in acute gouty arthritis rats to stimulate receptor expression

【Animal Modeling】-Effect of electroacupuncture on the expression of ankle joint myeloid cells in acute gouty arthritis rats to stimulate receptor expression

To explore the effect of electroacupuncture on the expression of stimulatory receptor (TREM)-1 in bone marrow cells of ankle synovial tissue in rats with acute gouty arthritis (AGA)...

2021-01-22
[Animal modeling]-Chloroquine inhibits airway hyperresponsiveness in asthmatic mice

[Animal modeling]-Chloroquine inhibits airway hyperresponsiveness in asthmatic mice

To explore the effect of chloroquine on airway hyperresponsiveness in asthmatic mice and its possible mechanism...

2021-01-22
[Animal modeling]-The role of advanced glycation end product receptors in lipopolysaccharide-mediated changes in the cytoskeleton of mouse lung microvascular endothelial cells

[Animal modeling]-The role of advanced glycation end product receptors in lipopolysaccharide-mediated changes in the cytoskeleton of mouse lung microvascular endothelial cells

Establish a method for isolating high-purity pulmonary microvascular endothelial cells, and observe the wild-type mouse cells and receptors in knockout mice with high glycation end products stimulated by lipopolysaccharide...

2021-01-22
【Animal Modeling】-Minocycline inhibits hyperpolarization activation currents of glial neurons in the spinal dorsal horn of rats

【Animal Modeling】-Minocycline inhibits hyperpolarization activation currents of glial neurons in the spinal dorsal horn of rats

To study the effect of minocycline on the hyperpolarization activation current (Ih) of glial neurons in the posterior horn of the spinal cord in rats...

2021-01-22
Difference analysis of basic physiological and biochemical indexes between male and female FMMU albino guinea pigs

Difference analysis of basic physiological and biochemical indexes between male and female FMMU albino guinea pigs

Measure and compare the blood indexes, heart rate, common carotid artery pressure, ventricular pressure, and organ parameters of female and male ordinary FMMU albino guinea pigs...

2021-01-21
【Animal Experiment】-Comparison of the pressure that can withstand the maxillary and frontal sinus mucosa of goat

【Animal Experiment】-Comparison of the pressure that can withstand the maxillary and frontal sinus mucosa of goat

Investigate the difference in the allowable pressure of the mucosa of the nasal sinuses of goats, analyze the reasons for this difference, and provide theoretical basis and guidance for the mucosal problems related to the maxillary sinus ridge...

2021-01-21
[Animal Experiment]-The role and mechanism of eNOS/NO pathway in renal interstitial microangiopathy in mice with unilateral ureteral obstruction

[Animal Experiment]-The role and mechanism of eNOS/NO pathway in renal interstitial microangiopathy in mice with unilateral ureteral obstruction

To explore the role and mechanism of endothelial nitric oxide synthase (eNOS) and nitric oxide (NO) in renal matrix fibrosis in mice with unilateral urinary tract obstruction (UUO)...

2021-01-21
【Animal Experiment】-The effect of endometriosis on the fertility of mice

【Animal Experiment】-The effect of endometriosis on the fertility of mice

Establish a mouse model of endometriosis and observe the effect of endometriosis on the fertility of model mice...

2021-01-21
[Animal experiment] The role of -ripply1 in the dorsal-ventral development of early zebrafish embryos

[Animal experiment] The role of -ripply1 in the dorsal-ventral development of early zebrafish embryos

To explore the role of ripply1 gene in the early development of zebrafish dorsoventral axis...

2021-01-21
【Animal Experiment】-Genetic Screening of Mutants with Developmental Defects in Zebrafish Digestive Organs

【Animal Experiment】-Genetic Screening of Mutants with Developmental Defects in Zebrafish Digestive Organs

Forward genetic screening of zebrafish mutants with defects in liver, intestine and gallbladder development...

2021-01-21
Application of rodent endotracheal intubation under direct vision guided by optical fiber

Application of rodent endotracheal intubation under direct vision guided by optical fiber

Establish a simple method to insert into rodents, and use this method to establish various animal models that require intratracheal infusion...

2021-01-21
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