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Scientists use gene editing technology to eliminate viruses in live pigs

Scientists use gene editing technology to eliminate viruses in live pigs

Scientists deactivate a family of retroviruses by editing the genome of pigs. These results have important implications for human transplantation medicine...

2020-11-17
High-throughput sequencing method to study the effect of different pH drinking water on the gut microbes of SPF mice

High-throughput sequencing method to study the effect of different pH drinking water on the gut microbes of SPF mice

To study the effect of different pH drinking water on the gut microbial diversity of SPF mice...

2020-11-17
Hydrogen-rich liquid reduces cerebral ischemia-reperfusion injury in rats through PI3K pathway

Hydrogen-rich liquid reduces cerebral ischemia-reperfusion injury in rats through PI3K pathway

To explore the effect of hydrogen-rich liquid on hippocampal neuron apoptosis and PI3K/Akt/FoxO1 signal pathway expression induced by cerebral ischemia-reperfusion in rats...

2020-11-17
Animal experiment: the effect of ovariectomy on skin aging in osteoporotic rats

Animal experiment: the effect of ovariectomy on skin aging in osteoporotic rats

The osteoporosis model constructed with ovariectomized rats is the most suitable model for studying postmenopausal osteoporosis. However, there is little research on the effect of the removal of the ovaries on the skin of rats...

2020-11-17
Animal experiment: anti-fatigue effect of maca extract on sports

Animal experiment: anti-fatigue effect of maca extract on sports

Explore the anti-fatigue effect of maca extract on sports...

2020-11-17
Animal experiment: Comparison of the effect of calcium chelated collagen peptide and estrogen on the bone quality of ovariectomized rats

Animal experiment: Comparison of the effect of calcium chelated collagen peptide and estrogen on the bone quality of ovariectomized rats

Compare the bone quality improvement effect of Calcium Chelated Collagen Polypeptide (CPCC) with estrogen, laying the foundation for the research and development of safe osteoporosis (OP) prevention and treatment drugs...

2020-11-17
Animal experiment: Safety pharmacology and subchronic toxicity evaluation of Jinqing granules

Animal experiment: Safety pharmacology and subchronic toxicity evaluation of Jinqing granules

There are about 12,000 kinds of Chinese medicines in clinical use, most of which are herbal medicine. The origin and development of Chinese medicine are the practical experience and medical practice of working people....

2020-11-17
Animal experiments: Studies have found that mice that lose their sense of smell after ingesting high-fat foods do not increase significantly

Animal experiments: Studies have found that mice that lose their sense of smell after ingesting high-fat foods do not increase significantly

The aroma of food is a key factor in inducing appetite. According to foreign media reports, a study now found that mice that temporarily lose their sense of smell while ingesting the same food are much lighter than control mice with normal sense of s...

2020-11-17
Therapeutic effect of nutritional supplements on retinopathy of diabetic rats

Therapeutic effect of nutritional supplements on retinopathy of diabetic rats

Retinopathy remains one of the most devastating complications of diabetes. Although basic science and clinical research have made significant progress to understand the complex pathophysiological mechanism of this blinding disease, the exact mechanis...

2020-11-17
Comparison of acute postoperative response and postoperative stress between video-assisted thoracoscopy and thoracotomy for small pigs

Comparison of acute postoperative response and postoperative stress between video-assisted thoracoscopy and thoracotomy for small pigs

Video-assisted thoracoscopic surgery (VATS) has been used as a diagnostic and therapeutic platform to perform various thoracic surgery operations...

2020-11-17
Study on the Effect and Mechanism of miR-221 in H2O2 Induced Cardiomyocyte Injury in Rats

Study on the Effect and Mechanism of miR-221 in H2O2 Induced Cardiomyocyte Injury in Rats

To explore the role and mechanism of miR-221 in the damage of rat cardiomyocytes (H9c2) induced by hydrogen peroxide (H2O2)...

2020-11-17
Effect of paclitaxel on the expression of CD28, CTLA-4 and BAFF in rats with experimental autoimmune encephalomyelitis

Effect of paclitaxel on the expression of CD28, CTLA-4 and BAFF in rats with experimental autoimmune encephalomyelitis

To explore the effect of paclitaxel on the expression of CD28 and CTLA-4 in the brain tissue of experimental autoimmune encephalomyelitis (EAE) rats and the content of B cell stimulating factor (BAFF) in the supernatant of spleen tissue and its signi...

2020-11-17
Effect of intrauterine injection of absolute ethanol on the estrous cycle of mice

Effect of intrauterine injection of absolute ethanol on the estrous cycle of mice

To investigate the effect of intrauterine injection of absolute ethanol on the estrous cycle of mice...

2020-11-17
Mouse experiments revealed that low-dose penicillin may induce long-term behavioral changes in offspring

Mouse experiments revealed that low-dose penicillin may induce long-term behavioral changes in offspring

In a research report published in the international journal Nature Communications, researchers from McMaster University and other institutions completed a landmark study. They found that low-dose penicillin was provided to pregnant mice clinically Ma...

2020-11-16
Changes of blood biochemical indexes in rats with chronic alcoholic liver injury after transplantation of human amniotic membrane mesenchymal stem cells

Changes of blood biochemical indexes in rats with chronic alcoholic liver injury after transplantation of human amniotic membrane mesenchymal stem cells

Studies have shown that human amniotic mesenchymal stem cells (hAMSCs) have a variety of differentiation and proliferation functions, which can induce differentiation into liver-like cells, thereby having a certain repair effect on liver injury...

2020-11-16
Pharmacokinetic study of multi-dose administration of granisetron hydrochloride transdermal patch in Beagle dogs

Pharmacokinetic study of multi-dose administration of granisetron hydrochloride transdermal patch in Beagle dogs

Establish a blood concentration determination method for granisetron hydrochloride transdermal patch in Beagle dogs. Through multi-dose administration in Beagle dogs, reveal the pharmacokinetics of granisetron hydrochloride transdermal patch in Beagl...

2020-11-16