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[Animal Modeling]-How to establish a hypoxic-ischemic brain injury model in newborn mice?

[Animal Modeling]-How to establish a hypoxic-ischemic brain injury model in newborn mice?

Improve the classic Vannucci method to establish a simple and stable neonatal rat model of hypoxic-ischemic brain damage...

2021-05-27
【Animal Modeling】-How to establish rat models of different degrees of chills?

【Animal Modeling】-How to establish rat models of different degrees of chills?

To study the temperature threshold of shivering during cryotherapy in hyperthermia rats, and to establish rat models of different degrees of shiver...

2021-05-27
【Animal Modeling】-How was the first hypothyroid pig model established?

【Animal Modeling】-How was the first hypothyroid pig model established?

Congenital hypothyroidism (hypo hypothyroidism) is an endocrine disorder caused by insufficient secretion of thyroid hormones...

2021-05-27
【Animal Modeling】-How to establish orthotopic xenograft model of glioma?

【Animal Modeling】-How to establish orthotopic xenograft model of glioma?

Establish a stable, real-time and monitorable nude mouse model of glioma allograft...

2021-05-26
【Animal Modeling】-How to verify the effect of psoralen on the mouse model of rheumatoid arthritis?

【Animal Modeling】-How to verify the effect of psoralen on the mouse model of rheumatoid arthritis?

To explore the effect of psoralen on rheumatoid arthritis induced by type Ⅱ collagen, and to preliminary explore the molecular mechanism of its effect...

2021-05-26
【Animal Modeling】-How to establish an induced mini-pig atherosclerosis model?

【Animal Modeling】-How to establish an induced mini-pig atherosclerosis model?

Establish a model of small atherosclerosis (AS) induced by high fat, and observe the expression changes of lipoprotein-related phospholipase A2 (Lp-PLA2) in plasma and plaques...

2021-05-26
【Animal Modeling】-How to establish a primary small intestinal epithelial cell model?

【Animal Modeling】-How to establish a primary small intestinal epithelial cell model?

To explore the proliferation characteristics of primary small intestinal epithelial cells of tree shrews, and establish an in vitro cell model of human rotatable G1P [8] virus infection of primary small intestinal epithelia of tree shrews...

2021-05-26
【Animal Modeling】-How to establish embryo chorioallantoic membrane transplantation tumor model?

【Animal Modeling】-How to establish embryo chorioallantoic membrane transplantation tumor model?

By comparing the growth of three different cancer cells in chicken chorionic villus (CAM), the best transplanted cancer cell line was screened, the transplanted tumor model was established, and its biological characteristics were observed...

2021-05-26
【Animal Modeling】-How to use targeted near-infrared fluorescent dyes in liver cancer models?

【Animal Modeling】-How to use targeted near-infrared fluorescent dyes in liver cancer models?

Explore the application of near-infrared fluorescence (IRRF) dye IR-783 in liver cancer model imaging research, and analyze the molecular mechanism of the dye targeting tumor cells...

2021-05-26
【Animal Modeling】-How to establish a rat model of diarrhea-type irritable bowel syndrome?

【Animal Modeling】-How to establish a rat model of diarrhea-type irritable bowel syndrome?

By observing the changes in rat symptoms, histopathology, visceral hypersensitivity, mast cell activation, autophagy, beclin-1 and claudin-2 and other related indicators, capsaicin gavage was performed. Symptoms of diarrheal irritable bowel syndrome ...

2021-05-26
【Animal Modeling】-Why use optogenetic technology to prepare animal models of nervous system diseases?

【Animal Modeling】-Why use optogenetic technology to prepare animal models of nervous system diseases?

Parkinson\\\'s disease, depression, anxiety, Alzheimer\\\'s disease and other neuropsychiatric diseases seriously endanger human health and cause a heavy burden on medical care...

2021-05-26
【Animal Modeling】-How to build a porcine myocardial infarction model of Potentilla hemp?

【Animal Modeling】-How to build a porcine myocardial infarction model of Potentilla hemp?

Establish the myocardial infarction model and clinically important model indicators in goose Potentilla piglets, and explore the correlation between the gene expression of myocardial infarction marginal zone and metabolic compensation...

2021-05-25
【Animal Modeling】-What are the pathological mechanisms of the asthma mouse model under the action of paeoniflorin?

【Animal Modeling】-What are the pathological mechanisms of the asthma mouse model under the action of paeoniflorin?

To observe the effect of medicinal glycosides on airway inflammation chemokines and their receptors in a mouse asthma model...

2021-05-25
【Animal Modeling】-Why establish a mouse model of Alzheimer\'s disease and PRNP mutant

【Animal Modeling】-Why establish a mouse model of Alzheimer's disease and PRNP mutant

Alzheimer\'s disease is one of the dementias that damage human nerves caused by β-amyloid, and there is no cure for it....

2021-05-25
【Animal Modeling】-How to establish hepatitis B virus infection model in vivo and in vitro

【Animal Modeling】-How to establish hepatitis B virus infection model in vivo and in vitro

The application of different types of HBV infection models in vivo and in vitro has greatly promoted the research of HBV biological characteristics, infection process, pathogenic mechanism, etc., as well as the development and evaluation of anti-HBV ...

2021-05-25
【Animal Modeling】-How to establish a rabbit model of limited photocell degeneration in a single eye?

【Animal Modeling】-How to establish a rabbit model of limited photocell degeneration in a single eye?

Retinitis Pigmentosa (RP) is a degenerative disease of the retina that can cause night blindness and eventually lead to loss of peripheral and central vision...

2021-05-25