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Refers to hypertension caused by cutting the decompression nerves of the aorta and the nerves of the carotid sinus. Experiments usually use dogs and rabbits, sometimes rats...
2021-03-22A model of extrarenal compressive hypertension with two kidneys and a tie (one kidney is tied and both kidneys are kept), one kidney and one tie (one kidney is tied) (contralateral nephrectomy), and one There are two types of tie that can be divided ...
2021-03-22The renovascular hypertension model is a model in which an animal\'s renal artery stenosis leads to an increase in blood pressure...
2021-03-22Male rats weighing 250-450g are anesthetized by intraperitoneal injection with 25% urethane at a dose of 1.2-1.5g/kg body weight. The animal is fixed on the operating table in a supine position, and needle electrodes are inserted into the rat’s limbs...
2021-03-18Male rats weighing 250-350g were anesthetized with ether and fixed in the supine position. Cut the skin in the middle of the neck, separate the trachea for tracheal intubation, connect to an artificial ventilator for artificial respiration, maintain ...
2021-03-18Experimental dogs weighing 10～13kg were anesthetized with 3% sodium pentobarbital at a dose of 30mg/kg body weight, and artificial respiration was performed by endotracheal intubation. The respiratory rate was 24b/min, the respiratory ratio was 1:1...
2021-03-18Experimental dogs weighing 12 to 15 kg are anesthetized by intravenous or intraperitoneal injection of 3% sodium pentobarbital at a dose of 30 mg/kg body weight. The median skin of the neck is incised, the trachea is separated for endotracheal intuba...
2021-03-18Experimental rats weighing 250-300g were anesthetized by intraperitoneal injection of 25% urethane and fixed in the supine position. According to the conventional method, needle electrodes were pierced into the extremities of the rats and connected t...
2021-03-18For mice weighing 25-30 g or more, use 3-4 ml chloroform cotton balls and place them in a 600 ml beaker (after replacement). Add 1 ml of chloroform to the mice. After stopping breathing, immediately remove the chest cavity and visually inspect the ve...
2021-03-18The animals used for the replication method are rats, dogs and rabbits. Here, we will introduce in detail how to use dogs to create an acute myocardial infarction model...
2021-03-17Breeding method After measuring the body weight, the experimental dog was anesthetized by intravenous administration of 3% sodium pentobarbital 30 mg/kg and inserted into the trachea. Fix the animal in the right decubitus position, separate the femor...
2021-03-17Replication method Male Wistar rats, weighing 300-400g. Wire: 0.36 mm in diameter, which can be reused. The wire can be shortened to 30 cm to improve operability...
2021-03-17Breeding method Chinese male miniature pigs weighing 18-22 kg. Anesthesia was given by intravenous injection of 30 mg/kg sodium pentobarbital. After the animal is fixed, the femoral vein is separated to establish a venous passage for hydration and dr...
2021-03-17Breeding method New Zealand rabbits weighing 2.0-2.5 kg, fixed on their back, local infiltration anesthesia with 1% procaine hydrochloride, aseptic surgery, incision in the chest, ribs, ligation, exposed area of the pericardium...
2021-03-17Breeding method New Zealand rabbits weighing 1.5-2.0 kg, the back is fixed, and 2% procaine is used for local infiltration anesthesia. A small incision is made in the center of the upper abdomen, and about 0.5 g of liver tissue is collected to check ...
2021-03-174-week-old SPF male BALB/c mice, weighing 10-12 g, keep the air in a fresh room with a temperature of (20±4)°C and a relative humidity of 60%. Inject 100,000 pfu CVB3 (Nancy strain, MCMV suspension) intraperitoneally at a volume of 0.1 ml/mouse...
2021-03-17