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In the early diagnosis and treatment of pancreatic cancer, it was found that the precancerous state of pancreatic cancer, that is, the molecular genetic abnormality of pancreatic duct epithelial tumors, is directly related to pancreatic cancer...
2021-03-10Introduce specific foreign genes into the genome of animals through genetic engineering methods, and integrate and replicate the genes to raise animals carrying the foreign genes...
2021-03-10Liver cancer model formed by transplanting liver cancer tissues, cell lines or other malignant tumors from animals or humans to animals...
2021-03-10The animal model of inducible liver cancer is a type of liver fiber that acts on experimental animals through chemical, physical and biological carcinogenic factors to induce the formation of animal liver cancer. The disease is a simulation of period...
2021-03-10By cutting the bile duct or injecting sclerosing agent, it will artificially block the extrahepatic bile duct, cause the bile duct to dilate, cholestasis, and increase the pressure in the bile duct above the blocked site....
2021-03-10By importing xenogeneic serum, the body\'s immune regulation is disordered, and immune complexes are deposited in the portal area, causing vasculitis and perivascular inflammation, activating fat storage cells to transform into fibroblasts, and activ...
2021-03-10Acetaldehyde is an intermediate metabolite of ethanol, which directly damages the liver, converts coenzyme I (NAD) into reduced coenzyme I (NADH) in the liver, and reduces the ratio of NAD/NADH, thereby inhibiting tricarboxylic acid...
2021-03-10By using both genetic modification and nutritional factors, it is possible to create animal models that conform to the laws of human NAFLD, such as ob/ob mice + MCD diet, db/db mice + MCD diet and Abcb11 mice...
2021-03-10![[Disease animal model]-Nutritional fatty liver model](/./uploads/images/20210310/60482a1035d97.png)
Frequent use of methionine-choline deficiency (MCD) diet to induce classic NAFLD animal models...
2021-03-10The researchers transplanted human hepatocytes into immunodeficient mice so that they can be infected with HCV and become a humanized mouse hepatitis C animal model, which is similar to the humanized hepatitis B mouse model...
2021-03-10
So far, a variety of HCV-related transgenic mouse models have been established, providing a powerful research tool for studying the relationship between HCV constituent genes and liver diseases...
2021-03-10The currently used HCV animal models mainly include chimpanzee hepatitis C model, tree sh hepatitis C model and rat hepatitis C model...
2021-03-10At present, the animal models of hepatitis B virus mainly include tree sh hepatitis B model, duck hepatitis B model, marmot hepatitis B model and mouse hepatitis B model...
2021-03-10Pituitary prostaglandin can severely contract the coronary arteries, cause acute dysfunction of the blood supply of myocardial tissue, increase peripheral resistance, increase the burden on the heart, myocardial ischemia, hypoxia, and even necrosis, ...
2021-03-09The same belongs to the open thoracic surgery method. The difference between electrocoagulation of coronary arteries and ligation methods is that electrocoagulation blocks the coronary arteries, and the current causes local myocardial tissue necrosis...
2021-03-09Myocardial infarction-type Watanabe rabbits are based on the WHHL rabbits with coronary atherosclerosis tendency, through continuous artificial selection of high plasma cholesterol levels, severe coronary atherosclerosis lesions, and the main disease...
2021-03-09