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【Disease Animal Modeling】-Preparation of Experimental Animal Model of Acute Pancreatitis

【Disease Animal Modeling】-Preparation of Experimental Animal Model of Acute Pancreatitis

Animal models of pancreatitis are the best way to study the causes of pancreatitis and explore clinical treatments, but the cause of pancreatitis is still unknown, and there is no good method, because the cause varies with the type of pancreatitis...

2021-03-08
【Disease animal model】-Establishment and identification of HL-60 cell animal model of acute promyelocytic leukemia

【Disease animal model】-Establishment and identification of HL-60 cell animal model of acute promyelocytic leukemia

  The 16th autosomal recessive mutation (SCID) of the mouse is a mutant mouse 1. The homozygous SCID mouse gene almost completely loses the function of mouse T and B lymphocytes, and has been widely used in this type of mouse. In immunology and oncol...

2021-03-08
[Animal disease model]-Preparation of sciatic nerve-gastrocnemius specimen of frog or toad

[Animal disease model]-Preparation of sciatic nerve-gastrocnemius specimen of frog or toad

Amphibians such as frogs and toads have the same basic life activities and physiological functions as warm-blooded animals, and can easily understand the living conditions of isolated tissues...

2021-03-08
[Disease animal model]-How to design a conditional gene knockout mouse model

[Disease animal model]-How to design a conditional gene knockout mouse model

Rats and mice can be said to be stars in life science laboratories. Successful rat and mouse models can be said to be \"excellent assistants in life sciences.\" Many people may want to design or understand conditional knockout mice....

2021-03-08
[Disease animal model]-Parkinson\'s disease animal model preparation

[Disease animal model]-Parkinson's disease animal model preparation

In order to simulate human Parkinson\'s disease, an ideal animal model should have the following characteristics: (1) The number and morphology of dopaminergic neurons at birth are normal, and they gradually decrease selectively during adolescence, r...

2021-03-08
【Animal Modeling】-Therapeutic effect of anti-C5aR antibody combined with allicin on induced inflammatory bowel disease in rats

【Animal Modeling】-Therapeutic effect of anti-C5aR antibody combined with allicin on induced inflammatory bowel disease in rats

  To explore the therapeutic effect of anti-complement 5a receptor (C5aR) antibody combined with allicin on inflammatory bowel disease (IBD) in rats...

2021-03-05
【Animal Modeling】-The effect of Huangqi injection on the mRNA expression of IL-1β, MCP-1 and TNF-α in the kidney of db/db mice

【Animal Modeling】-The effect of Huangqi injection on the mRNA expression of IL-1β, MCP-1 and TNF-α in the kidney of db/db mice

To explore the regulation effect of astragalus injection on immune cells and inflammatory factors in db/db mice and its possible mechanism...

2021-03-05
【Animal Modeling】-The effect and mechanism of rapamycin on myocardial injury after renal ischemia-reperfusion in rats

【Animal Modeling】-The effect and mechanism of rapamycin on myocardial injury after renal ischemia-reperfusion in rats

To explore the effect of rapamycin (RAPA) on the damage to the heart of distant organs after renal ischemia-reperfusion (RIR) in rats...

2021-03-04
【Animal Modeling】-Study on the anti-tumor effect of Xiuzhen mushroom powder on H22 tumor-bearing mice

【Animal Modeling】-Study on the anti-tumor effect of Xiuzhen mushroom powder on H22 tumor-bearing mice

To study the anti-tumor effect of Xiuzhen mushroom and its mechanism...

2021-03-04
【Animal Modeling】-The effect of hydroxychloroquine on the spleen lymphocytes of lupus mice

【Animal Modeling】-The effect of hydroxychloroquine on the spleen lymphocytes of lupus mice

Observe the effect of hydroxychloroquine on the distribution of lymphocytes in the peripheral immune system (spleen) of mice with systemic lupus erythematosus (TC mice)...

2021-03-04
【Animal Modeling】-The protective effect of zedoary ketone on the cognitive function and nerve function of mice with cerebral ischemia-reperfusion injury

【Animal Modeling】-The protective effect of zedoary ketone on the cognitive function and nerve function of mice with cerebral ischemia-reperfusion injury

To explore the effects of zedoary ketone on the cognitive function, neurological function and mechanism of cerebral ischemia-reperfusion injury in mice...

2021-03-04
【Animal Modeling】-Effects of Different Exercise Mode Interventions on the Emotional Behavior of Aggressive Rats

【Animal Modeling】-Effects of Different Exercise Mode Interventions on the Emotional Behavior of Aggressive Rats

To study the effects of various exercise interventions on the emotional behavior of aggressive rats...

2021-03-04
【Animal Modeling】-Preliminary study on serum cytokine expression profile of collagen-induced arthritis/syndrome model rats

【Animal Modeling】-Preliminary study on serum cytokine expression profile of collagen-induced arthritis/syndrome model rats

To study the expression of serum cytokines in collagen-induced rheumatoid arthritis, cold-damp arthritis and damp-heat arthralgia/syndrome model rats...

2021-03-02
【Animal Modeling】-Using black-spotted double-finned electric rays to construct experimental autoimmune myasthenia gravis mouse model

【Animal Modeling】-Using black-spotted double-finned electric rays to construct experimental autoimmune myasthenia gravis mouse model

How to establish an experimental autoimmune myasthenia gravis animal model that meets the international preclinical experimental standards?...

2021-03-02
【Animal Modeling】-Establishment and Evaluation of Rat Model of Chronic Fallopian Tube Inflammation of Qi Stagnation and Blood Stasis Type

【Animal Modeling】-Establishment and Evaluation of Rat Model of Chronic Fallopian Tube Inflammation of Qi Stagnation and Blood Stasis Type

Will we explore the method of establishing a chronic salpingitis model with stagnation and hyperemia, study its feasibility, conduct a preliminary evaluation of the model, and lay the foundation for further experimental research?...

2021-03-02
【Animal Modeling】-Establishment of a dual-target mouse model of myocardial ischemia and atherosclerotic plaque angiogenesis

【Animal Modeling】-Establishment of a dual-target mouse model of myocardial ischemia and atherosclerotic plaque angiogenesis

Explore an effective method to establish a dual-target mouse model of myocardial ischemia and atherosclerotic plaque angiogenesis?...

2021-03-02