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[Disease animal model]-Norepinephrine-induced rabbit cardiomyopathy model

[Disease animal model]-Norepinephrine-induced rabbit cardiomyopathy model

Injecting large amounts of norepinephrine into rabbits will increase myocardial load, myocardial degeneration and necrosis, and may cause DCM and congestive heart failure...

2021-03-09
[Disease animal model]-Spontaneous cardiomyopathy animal model

[Disease animal model]-Spontaneous cardiomyopathy animal model

The BIO14.6 hamster spontaneous cardiomyopathy model has been used for more than 30 years...

2021-03-09
【Disease animal model】-Mediastinal nerve atrial tachycardia model

【Disease animal model】-Mediastinal nerve atrial tachycardia model

The medial nerve is a mixed nerve plexus, including the parasympathetic preganglionic nerve, sympathetic afferent nerve and limb afferent nerve...

2021-03-09
【Disease animal model】-vagus atrial fibrillation model

【Disease animal model】-vagus atrial fibrillation model

Studies have shown that the vagus nervous system may be involved in the formation and maintenance of atrial fibrillation, especially related to pulmonary venous atrial fibrillation...

2021-03-09
[Disease animal model]-rapid atrial pacing atrial fibrillation model

[Disease animal model]-rapid atrial pacing atrial fibrillation model

The rapid atrial pacing atrial fibrillation model is currently the most studied and most widely used animal model of chronic atrial fibrillation...

2021-03-09
[Disease animal model]-Myocardial ischemia and myocardial infarction animal model

[Disease animal model]-Myocardial ischemia and myocardial infarction animal model

Methods to replicate animal myocardial ischemia and myocardial infarction models include ligation of coronary arteries and some left circumflex coronary arteries, most of which ligate the anterior descending branch of the left coronary artery...

2021-03-09
【Disease Animal Model】-Arrhythmia Model

【Disease Animal Model】-Arrhythmia Model

Arrhythmia can be reproduced in the whole animal, or perfused in vitro by in vitro perfusion of the isolated heart or specific parts of the heart, depending on various experimental purposes...

2021-03-09
【Disease Animal Model】-Atherosclerosis Model

【Disease Animal Model】-Atherosclerosis Model

High-cholesterol and high-fat feed method: At present, it is a more commonly used method, which has the characteristics of low mortality and long-term observation, but it is time-consuming. Usually, rabbits, pigeons, chickens, etc. can cause obvious ...

2021-03-09
【Disease animal model】-all gene knockout mice

【Disease animal model】-all gene knockout mice

Whole gene knockout is to replace the target gene with a foreign DNA sequence (in most cases, the neomycin resistance gene used for drug screening), so as to achieve the purpose of inactivating the target gene...

2021-03-08
【Disease animal model】-H7N9 avian influenza virus mouse infection animal model

【Disease animal model】-H7N9 avian influenza virus mouse infection animal model

Mice were randomly divided into normal saline control group, high, medium, and low infection dose groups according to their body weight. Each group was 10 mice and were inoculated with 1×108, 1×107 or 1×106 TCID50 virus to observe clinical symptoms a...

2021-03-08
[Disease animal model]-rat model of high altitude polycythemia

[Disease animal model]-rat model of high altitude polycythemia

Altitude sickness (called \"altitude sickness\") is a chronic altitude sickness caused by excessive red blood cell proliferation (excessive red blood cell proliferation) caused by high altitude hypoxia...

2021-03-08
【Disease animal model】-guinea pig experimental allergic neuritis model

【Disease animal model】-guinea pig experimental allergic neuritis model

Extraction and identification of bovine sciatic nerve myelin basic protein (MBP)  ① Extraction of MBP: modified according to London method...

2021-03-08
【Disease Animal Models】-Animal Models of Respiratory System Diseases (Animal Models)

【Disease Animal Models】-Animal Models of Respiratory System Diseases (Animal Models)

Rats, guinea pigs and monkeys that inhale irritating gases (sulfur dioxide, chlorine, ammonia, smoke, etc.) are often selected to replicate chronic bronchitis in humans...

2021-03-08
【Disease animal model】-Chinese Academy of Sciences scientists prepared a rhesus monkey model for Parkinson\'s disease for the first time

【Disease animal model】-Chinese Academy of Sciences scientists prepared a rhesus monkey model for Parkinson's disease for the first time

Parkinson’s disease is the world’s second largest neurodegenerative disease after Alzheimer’s, posing a serious threat to the health of middle-aged and elderly people...

2021-03-08
【Disease Animal Model】-Establishment of Tree Shrew Hand, Foot and Mouth Disease Model

【Disease Animal Model】-Establishment of Tree Shrew Hand, Foot and Mouth Disease Model

Coxsackie virus A16 (CA16) is generally considered to be one of the main pathogens of human hand, foot and mouth disease. The clinical manifestations of hand, foot and mouth disease include small vesicles on the hands, feet and mouth, as well as seve...

2021-03-08
【Disease Animal Model】-Reproduction of arrhythmia animal model

【Disease Animal Model】-Reproduction of arrhythmia animal model

Arrhythmia can be reproduced in the whole animal, or in vitro perfused through the isolated heart or specific parts of the heart, depending on various experimental purposes...

2021-03-08