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【Animal Modeling】-What is the role of RhoA/ROCK signaling pathway in the rat model of pulmonary hypertension caused by left heart disease?

【Animal Modeling】-What is the role of RhoA/ROCK signaling pathway in the rat model of pulmonary hypertension caused by left heart disease?

To explore the expression level and role of RhoA/ROCK signaling pathway in a rat model of left heart disease-related pulmonary hypertension...

2021-12-24
【Animal Modeling】-How to establish a mouse testis in vitro culture model?

【Animal Modeling】-How to establish a mouse testis in vitro culture model?

Establish a mouse testicular organ culture model by looking for suitable culture conditions...

2021-12-24
【Animal Modeling】-Animal Model of Mouse Dissecting Aneurysm

【Animal Modeling】-Animal Model of Mouse Dissecting Aneurysm

To study the effect of β-aminopropionitrile (BAPN) on the aortic wall of rats, compare the characteristics of human dissecting aneurysms, and further establish an anatomical aneurysm animal model that meets the characteristics of human diseases. Do y...

2021-12-24
【Animal Modeling】-The effect of inflammatory factor storm on immune response to infection in aged mice

【Animal Modeling】-The effect of inflammatory factor storm on immune response to infection in aged mice

After the highly pathogenic avian influenza infects mice, will over-expressed inflammatory factors or inflammatory factor storms be detected in the lungs? Is high inflammation more common in older people infected?...

2021-12-24
【Animal Modeling】-Animal model of acute gastric ulcer induced by pyloric ligation

【Animal Modeling】-Animal model of acute gastric ulcer induced by pyloric ligation

Replication method Fasting adult rats for 48 hours, anesthetize with water, incise the abdominal wall to expose the stomach, pull the stomach out of the abdominal cavity with blunt forceps, and ligate the stomach at the joint with surgical sutures...

2021-12-24
Osteoporotic tree shrew model with ovariectomized method-[animal modeling]

Osteoporotic tree shrew model with ovariectomized method-[animal modeling]

Reproduction of human postmenopausal osteoporotic tree shrew model by surgical bilateral ovarian castration...

2021-12-24
【Animal Modeling】-Preliminary Exploration and Thinking of Small Animal Model of Norovirus Infected by Tree Shrew

【Animal Modeling】-Preliminary Exploration and Thinking of Small Animal Model of Norovirus Infected by Tree Shrew

How to explore the feasibility of establishing a tree h virus infection model through tube feeding and attack?...

2021-12-24
【Animal Modeling】-animal model of inhalation lung injury

【Animal Modeling】-animal model of inhalation lung injury

According to various experimental goals, is it important to select a suitable animal model of haze inhalation lung injury for the clinical mechanism of haze inhalation lung injury disease?...

2021-12-24
【Animal Modeling】-Zebrafish Alzheimer\'s Disease Drug Screening Model

【Animal Modeling】-Zebrafish Alzheimer's Disease Drug Screening Model

Alzheimer’s disease (Alzheimer’sdisease, AD), commonly known as Alzheimer’s, is a chronic degenerative brain degenerative disease that occurs in old age and pre-age. The main characteristics are progressive memory loss, cognitive impairment, personal...

2021-12-24
[Animal Modeling]-Chronic experimental epilepsy model caused by zinc sulfate

[Animal Modeling]-Chronic experimental epilepsy model caused by zinc sulfate

Copy method A healthy male rabbit weighs 2-3 kg. The procedure is the same as the ferrous sulfate model...

2021-12-24
【Animal Modeling】-Non-alcoholic fatty liver disease cynomolgus monkey model

【Animal Modeling】-Non-alcoholic fatty liver disease cynomolgus monkey model

Establish a non-alcoholic fatty liver cynomolgus monkey model induced by high-fat feed, analyze the effect of high-fat feed feeding time on the formation of animal NAFLD, and determine the feeding time of high-fat feed...

2021-12-24
【Animal Model】-Specific Myocardial Ischemia Model

【Animal Model】-Specific Myocardial Ischemia Model

By observing the expression of HE staining in myocardial tissue slices caused by subcutaneous injection of isoproterenol for different days (1 mg/kg body weight), observing the expression of VEGF (vascular endothelial growth factor) and FCF (fibrobla...

2021-12-24
【Animal Modeling】-Establishment of a new advanced liver tumor animal model based on intrahepatic portal vein injection of tumor cells

【Animal Modeling】-Establishment of a new advanced liver tumor animal model based on intrahepatic portal vein injection of tumor cells

Establish a new animal model of advanced liver tumor by injecting tumor cells into the portal vein...

2021-12-24
【Animal Modeling】-Portal hypertension model induced by intraportal injection of Bletilla powder plug in rabbits

【Animal Modeling】-Portal hypertension model induced by intraportal injection of Bletilla powder plug in rabbits

Replication method Anesthetize New Zealand male rabbits by conventional methods, enter the abdominal cavity through a midline incision under the xiphoid process, puncture the proximal portal vein with an indwelling needle, and measure the pressure of...

2021-12-24
What is the method of fluorescent PCR detection of mouse polyoma virus? -【Animal Modeling】

What is the method of fluorescent PCR detection of mouse polyoma virus? -【Animal Modeling】

Establish a fluorescent quantitative PCR detection method for polyoma virus, and study the polyoma virus infection in nude mice...

2021-12-23
In vitro and animal models for SARS-CoV-2 research

In vitro and animal models for SARS-CoV-2 research

The Chinese Center for Disease Control and Prevention (CCDC) has identified a new type of coronavirus infection as the cause of this pneumonia...

2021-12-23