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【Animal Modeling】-Animal Model of Acute Gastric Ulcer Induced by Chemicals

【Animal Modeling】-Animal Model of Acute Gastric Ulcer Induced by Chemicals

Reproduction method: adult experimental mice, fast for 48 hours, absolute ethanol (5 ml/kg body weight) or acetylsalicylic acid (200 mg/kg body weight), or 0.6 mol/L hydrochloric acid (10 ml/kg) for 1 hour Later, the animals were sacrificed by cervic...

2021-11-06
Changes of Blood Indexes in Long-term Toxicity Tests of Niaotong Kak Naiqi Tablets

Changes of Blood Indexes in Long-term Toxicity Tests of Niaotong Kak Naiqi Tablets

To explore the changes of hematological indexes in the rat long-term toxicity test of Uotongkaknaiqi tablets...

2021-11-06
【Disease animal model】-animal model of rat cerebral palsy

【Disease animal model】-animal model of rat cerebral palsy

Newborn rats underwent ligation of the right common carotid artery under awake and local anesthesia. The animals were placed in a constant temperature airtight glass container and vented with a mixed gas of 8% oxygen + 92% nitrogen. After 2 hours, th...

2021-11-06
[Animal experiment]-Vaccine targeting RBP-4 reduces blood sugar in type 2 diabetic mice

[Animal experiment]-Vaccine targeting RBP-4 reduces blood sugar in type 2 diabetic mice

Explore the effectiveness and feasibility of vaccine immune intervention with human-derived RBP-4 as the target of insulin resistance, and provide basic research data for the further development of new therapies for type 2 diabetes...

2021-11-06
[Animal Modeling]-Gene Cloning and Preliminary Function Study of Junction Adhesion Molecule A

[Animal Modeling]-Gene Cloning and Preliminary Function Study of Junction Adhesion Molecule A

To obtain the full-length coding sequence of the conjugative adhesion molecule A (AJAM-A), analyze its molecular characteristics, and use JAM as the receptor for Leovirus that invades the primary lung cells of the conjugative adhesion molecule...

2021-11-06
[Animal Modeling]-Preparation of a mouse model of chronic myocardial ischemia induced by different doses of isoproterenol and establishment of evaluation criteria

[Animal Modeling]-Preparation of a mouse model of chronic myocardial ischemia induced by different doses of isoproterenol and establishment of evaluation criteria

To establish a mouse chronic myocardial ischemia model by subcutaneously injecting different doses of isoproterenol (ISO) into the neck, determine the best model dose through comparison, and refer to the preparation of related models to find more obj...

2021-11-06
Diabetes model of Beagle dogs induced by high-fat feeding combined with streptozotocin

Diabetes model of Beagle dogs induced by high-fat feeding combined with streptozotocin

Use high-fat feeding combined with streptozotocin (STZ) to construct Beagle dog T2DM model and observe its related characteristics...

2021-11-06
【Animal Modeling】-Preliminary Study on the Mechanism of Hypoxic Preconditioning to Reduce the Susceptibility of Rats to Epilepsy and Its Brain Protection

【Animal Modeling】-Preliminary Study on the Mechanism of Hypoxic Preconditioning to Reduce the Susceptibility of Rats to Epilepsy and Its Brain Protection

Preliminary study on the effect of intermittent hypoxic preconditioning (IHP) on rat epileptic seizures induced by Li-pilo and its brain protection mechanism...

2021-11-06
【Animal Modeling】-An animal model of T lymphocyte deficiency?

【Animal Modeling】-An animal model of T lymphocyte deficiency?

The clinical manifestations of animals with T lymphocyte immune dysfunction are lack of hair and thymic hypoplasia...

2021-11-06
【Animal Modeling】-The alleviating effect of formononetin on osteoporosis in Ⅱ diabetic rats

【Animal Modeling】-The alleviating effect of formononetin on osteoporosis in Ⅱ diabetic rats

  To explore the palliative effect of Fulenaetine on osteoporosis in rats with type 2 diabetes and diabetic bone disease...

2021-11-06
【Animal Modeling】-Effects of long-term consumption of Polygonum multiflorum on hematopoietic system in mice

【Animal Modeling】-Effects of long-term consumption of Polygonum multiflorum on hematopoietic system in mice

To study the changes of hematopoietic system in mice after long-term intake of Polygonum multiflorum...

2021-11-06
【Animal Modeling】-Comparison of three methods of tracheal perfusion with bleomycin to induce lung fibrosis in mice

【Animal Modeling】-Comparison of three methods of tracheal perfusion with bleomycin to induce lung fibrosis in mice

Three different methods were used to intubate C57BL/6J mice to induce pulmonary fibrosis, using lumbar needle tracheal intubation, indwelling needle tracheal intubation and tracheostomy to study the tracheal intubation model...

2021-11-06
【Animal Modeling】-High-fat and vitamin D-induced atherosclerosis model in rats

【Animal Modeling】-High-fat and vitamin D-induced atherosclerosis model in rats

Feeding method: Add a high-fat diet (cholesterol 2%, autumn sodium 0.5%, lard 3%, propylthiouracil 0.2%, basic feed 94.3%) and vitamin D3 powder (1.25×1000000U/) to the body weight Experimental rat...

2021-11-06
[Animal Modeling]-Revealing the characteristics of SARS-CoV-2 infection of primates

[Animal Modeling]-Revealing the characteristics of SARS-CoV-2 infection of primates

Scientists from Texas Biomedical Company and Southwest National Primate Research Center (SNPRC) published their findings in the study of a comprehensive animal model of SARS-CoV-2 in natural microbiology...

2021-11-06
【Disease Animal Model】-Induced Rheumatoid Arthritis Animal Model

【Disease Animal Model】-Induced Rheumatoid Arthritis Animal Model

So far, induced animal models are the most widely used in RA research. It can be made not only with rodents, but also rabbits, dogs and monkeys. There are many types of inducers, among which AA model, CIA model and OIA model have been reported more...

2021-11-06
How to establish a focal cerebral ischemia model? -Animal modeling

How to establish a focal cerebral ischemia model? -Animal modeling

Observe the feasibility of electrocoagulation on the middle cerebral artery in mice, occlude the middle cerebral artery, and provide the possibility to establish a mouse cerebral ischemia model...

2021-11-06