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【Animal Modeling】-The neuroprotective effect and mechanism of Dendrobium officinale on MPTP-induced PD mice

【Animal Modeling】-The neuroprotective effect and mechanism of Dendrobium officinale on MPTP-induced PD mice

To investigate the neuroprotective effect of Dendrobium officinale extract in a mouse model of Parkinson\'s disease induced by 1-methylv-4-phenyl-1,2,3,6-tetrahydropyridine...

2022-09-24
【Animal modeling】-Comparative study on the pharmacokinetics of Eucommia ulmoides extract in normal rats and SHR models after multiple administrations

【Animal modeling】-Comparative study on the pharmacokinetics of Eucommia ulmoides extract in normal rats and SHR models after multiple administrations

To study the effect of 7 active components of pinoresinol diglucoside, geniposide chlorogenic acid, protocatechuic acid, neochlorogenic acid, cryptochlorogenic acid and pinoresinol monoglucoside after repeated administration of Eucommia ulmoides extr...

2022-09-24
【Animal modeling】-The improvement effect of Baixiangdan capsule on premenstrual anxiety disorder caused by ovariectomy in rats

【Animal modeling】-The improvement effect of Baixiangdan capsule on premenstrual anxiety disorder caused by ovariectomy in rats

To compare traditional Chinese medicine Baixiangdan Capsules (BXD), serotonin 3 receptor (5-HT3R) specific agonists and their antagonists, cannabinoid receptor 1 (CB1R) specific agonists and their antagonists through a series of behavioral tests. Int...

2022-09-24
【Animal modeling】-Protective effect of amygdalin on necrotizing enterocolitis in neonatal rats

【Animal modeling】-Protective effect of amygdalin on necrotizing enterocolitis in neonatal rats

To analyze the protective effect of amygdalin on necrotizing enterocolitis (NEC) in neonatal rats...

2022-09-24
【Animal Modeling】-Anesthesia effect of Shutai and Lumianning compound doses on Bama miniature pigs

【Animal Modeling】-Anesthesia effect of Shutai and Lumianning compound doses on Bama miniature pigs

To study the anesthesia effect of Shutai and Lu Mianning compound anesthesia on Bama miniature pigs, and to preliminarily observe the effect of anesthesia on the physiological indexes of miniature pigs...

2022-09-24
【Animal modeling】-Effect of low expression of lipoic acid synthase on antioxidant capacity in mice

【Animal modeling】-Effect of low expression of lipoic acid synthase on antioxidant capacity in mice

To establish a genetically modified mouse with low expression of lipoic acid synthase gene, and to test its antioxidant capacity...

2022-09-24
【Animal Modeling】-Analysis of the effects of different hypoxia exposure modes on differential gene expression of rat tibialis anterior muscle based on RNA sequencing

【Animal Modeling】-Analysis of the effects of different hypoxia exposure modes on differential gene expression of rat tibialis anterior muscle based on RNA sequencing

To screen the differentially expressed genes and their related pathways in rat tibialis anterior muscle from chronic intermittent hypoxia exposure and acute hypoxia exposure...

2022-09-24
【Animal modeling】-Effect of Jiayankangtai granules on immune-related cytokines in autoimmune thyroiditis rats

【Animal modeling】-Effect of Jiayankangtai granules on immune-related cytokines in autoimmune thyroiditis rats

To detect the effect of Jiayankangtai granules on immune-related cytokines in autoimmune thyroiditis rats, and to explore the mechanism of Jiayankangtai granules in improving autoimmune thyroiditis...

2022-09-24
【Animal Modeling】-Effect and mechanism of Bushen Yiqi Huayu Granule on the formation of blood vessels in ovariectomized osteoporosis model rats

【Animal Modeling】-Effect and mechanism of Bushen Yiqi Huayu Granule on the formation of blood vessels in ovariectomized osteoporosis model rats

To explore the effect of Bushen Yiqi Huayu Granule on angiogenesis in osteoporosis rats based on TLRs/NF-κB signaling pathway...

2022-09-24
【Animal modeling】-Kallikrein alleviates oxidative stress and fibrosis in rats with myocardial ischemia-reperfusion injury

【Animal modeling】-Kallikrein alleviates oxidative stress and fibrosis in rats with myocardial ischemia-reperfusion injury

To investigate the effect of pancreatic kininogenase on myocardial injury, oxidative stress and fibrosis in rats with myocardial ischemia-reperfusion injury...

2022-09-24
【Animal modeling】-Based on autophagy to investigate the effect of fentanyl combined with propofol on cardiac ischemia-reperfusion injury in rats

【Animal modeling】-Based on autophagy to investigate the effect of fentanyl combined with propofol on cardiac ischemia-reperfusion injury in rats

To investigate the effect of fentanyl combined with propofol on cardiac ischemia-reperfusion injury in rats based on autophagy...

2022-09-24
【Animal modeling】-The regulatory effect of curcumin and/or aerobic exercise on intestinal function in rats with dyslipidemia

【Animal modeling】-The regulatory effect of curcumin and/or aerobic exercise on intestinal function in rats with dyslipidemia

To investigate the regulatory effect of curcumin and/or aerobic exercise on intestinal function in rats with dyslipidemia...

2022-09-24
【Animal Modeling】-Effects of MED1 deletion in macrophages on blood glucose levels and insulin resistance in mice

【Animal Modeling】-Effects of MED1 deletion in macrophages on blood glucose levels and insulin resistance in mice

To study the regulatory role of macrophage MED1 in the occurrence of insulin resistance...

2022-09-24
【Animal Modeling】-Effect of Compound Microecological Preparations on Intestinal Immune Function in Mice

【Animal Modeling】-Effect of Compound Microecological Preparations on Intestinal Immune Function in Mice

To study the effect of compound probiotics on intestinal mucosal immune function in mice...

2022-09-24
【Animal modeling】-Protective effect of Dahuang Mudan decoction on liver injury in rats with acute pancreatitis

【Animal modeling】-Protective effect of Dahuang Mudan decoction on liver injury in rats with acute pancreatitis

To investigate the protective effect of Dahuang Mudan Decoction on liver injury in rats with acute pancreatitis...

2022-09-24
【Animal modeling】-Study on the effect of Siwu mixture on oxytocin-induced primary dysmenorrhea model mice

【Animal modeling】-Study on the effect of Siwu mixture on oxytocin-induced primary dysmenorrhea model mice

To study the effect of Siwu Mixture on the mouse model of primary dysmenorrhea, and to explore its possible mechanism...

2022-09-24