【Animal Modeling】-Using Orthogonal Test to Optimize the Establishment of a Rat Conditioned Fear Memory Model

To optimize the optimal experimental parameters for establishing a conditioned fear memory model in rats by using orthogonal experiments, and to find the optimal experimental conditions...

2022-09-13

【Animal Modeling】-Analysis of Mozart's K448 Sonata High-frequency Sound Wave on Intervention and Treatment of Depression Model in Mice

To establish a depression model in C57BL/6 mice, and to preliminarily explore the effect of high-frequency sound waves in Mozart\'s K448 sonata on improving depressive symptoms in C57BL/6 mice...

2022-09-13

【Animal Modeling】-Construction of a Bioluminescent Human Liver Cancer Nude Mouse Model of Carcinoma In Situ

To select a human hepatoma cell line (HCCLM3-Luc) stably expressing a luciferase reporter gene, and to construct an in situ tumor-bearing nude mouse model of human hepatoma cell line...

2022-09-13

【Animal modeling】-Establishment of an inflammatory model of BALB/c mice infected with influenza A virus

To analyze the pathogenicity of influenza A virus using a mouse model of inflammation...

2022-09-13

【Animal Modeling】-Comparison of Two Hepatitis B Hepatitis B Fibrosis Mouse Compound Models

To use C57BL/6N-Tg(1.28HBV)/Vst hepatitis B virus transgenic mice and rAAV8-1.3HBV adeno-associated virus-transfected mice combined with CCl4 intraperitoneal injection to induce hepatitis B fibrosis mouse model, and compare the two mice Virological a...

2022-09-13

【Animal modeling】-β-aminopropionitrile-induced rat model of dissecting aneurysm establishment

To explore the effect of β-aminopropionitrile on the wall of the aorta in mice, and to compare the pathogenesis of human dissecting aneurysm, in order to further explore the animal model of dissecting aneurysm with the characteristics of human diseas...

2022-09-13

【Animal Modeling】-Preliminary Study on Rhesus Monkey Model Infected by Human Coxsackie B2 Virus

To provide experimental methods and technical support for the establishment of human coxsackie B2 virus infection model in rhesus macaques by preliminarily analyzing the infection characteristics of human coxsackie B2 virus in rhesus monkeys through ...

2022-09-13

【Animal modeling】-Establishment and significance of nerve electrophysiological detection model during dorsal penile neurectomy in Beagle dogs

To investigate the detection method of penile somatosensory evoked potentials in beagle dogs under general anesthesia and the changes of somatosensory evoked potentials in the process of dorsal penile nerve resection, so as to provide reference for f...

2022-09-13

【Animal modeling】-improved reduction of uterine blood perfusion to establish a rat model of preeclampsia

To explore the method of establishing a rat model of preeclampsia...

2022-09-13

【Animal Modeling】-Establishment and evaluation of a mouse model of coronary heart disease-derived intestinal flora

To establish a mouse model of coronary heart disease-derived intestinal flora by fecal bacteria transplantation and evaluate the model...

2022-09-13

【Animal modeling】-Protective effect of hemorrhoids magnetized ointment on mouse hemorrhoid model

To study the protective effect of hemorrhoid magnetization ointment on acetic acid-induced hemorrhoids in mice...

2022-09-13

【Animal modeling】-Establishment of acute and chronic hyperuricemia models

To establish acute mouse and chronic rat hyperuricemia models, and use positive drugs to verify the curability of the two models, so as to provide model tools for the development of anti-hyperuric acid drugs...

2022-09-13

【Animal Modeling】-An improved method for establishing myocardial ischemia-reperfusion injury model in rats

To comprehensively evaluate the improved method for establishing myocardial ischemia-reperfusion injury model in rats...

2022-09-13

【Animal Modeling】-Gene-modified SLE mouse model

Transgenic mouse model B6.Cg-Tg (Actb-TNFRSF6B) 754Jwu/J, gene knock-in mouse model 129S6.129X1 (B6)-Ptprctm1Weis / and many other types of transgenic mouse models for studying autoimmune diseases Have. J and B6.129X1-Ptprctm1Weis/J, gene knockout mo...

2022-09-13

【Animal modeling】-Protective effect of stilbene glycosides inhibiting NADPH oxidase on cerebral ischemia/reperfusion injury in mice

To investigate the protective effect of stilbene glycoside (TSG) inhibiting NADPH oxidase on cerebral ischemia-reperfusion (I/R) injury in mice...

2022-09-13

【Animal modeling】-Effect of Fkbp51 knockout on alternative splicing of mouse liver transcriptome

To study the effect of Fkbp51 knockout on gene alternative splicing in liver tissue by analyzing the expression profiles of Fkbp51 gene knockout and wild-type mice livers...

2022-09-12