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【Animal Modeling】-The impact of unexpected stress on the immunity and microbial flora of the rat’s digestive tract

【Animal Modeling】-The impact of unexpected stress on the immunity and microbial flora of the rat’s digestive tract

By observing rats after 9 days of unpredictable stress stimulation intervention, analyze the impact of unpredictable stress stimulation on the immune system and microbial populations of the gastrointestinal tract, and provide reference materials for ...

2021-08-05
[Animal Modeling]-Research on the Effect of Puffing on the Nutritional Components of Experimental Dog Food

[Animal Modeling]-Research on the Effect of Puffing on the Nutritional Components of Experimental Dog Food

Dogs are one of the first animals to be domesticated. In the 1940s, dogs began to be used as experimental animals for research...

2021-08-05
【Animal Modeling】-The effect of long-term administration of Fumikang vaginal suppository on the blood physiological and biochemical indexes of rabbits

【Animal Modeling】-The effect of long-term administration of Fumikang vaginal suppository on the blood physiological and biochemical indexes of rabbits

Observe the effects of long-term administration of Fomikang vaginal suppository on blood physiology and biochemistry in rabbits, and provide scientific basis for clinical safe administration...

2021-08-05
[Animal modeling]-Intervention of electroacupuncture on activation of dorsal root ganglion satellite glial cells and P2X7 receptor expression in rats with inflammatory pain

[Animal modeling]-Intervention of electroacupuncture on activation of dorsal root ganglion satellite glial cells and P2X7 receptor expression in rats with inflammatory pain

To observe the effects of electroacupuncture on the mechanical pain threshold (foot withdrawal threshold, PWT) of the dorsal root ganglion (DRG) of rats with chronic inflammatory pain and activation of satellite glial cells and P2X7 receptors...

2021-08-05
[Animal modeling]-Serum metabonomics study of isoproterenol-induced cardiac hypertrophy in rats

[Animal modeling]-Serum metabonomics study of isoproterenol-induced cardiac hypertrophy in rats

Search for important biomarkers through the serum metabolome to explore the cause of myocardial hypertrophy in rats...

2021-08-05
[Animal modeling]-Correlation between the expression of BDNF and VEGF in hippocampus and forebrain cortex and depression induced by chronic stress in mice

[Animal modeling]-Correlation between the expression of BDNF and VEGF in hippocampus and forebrain cortex and depression induced by chronic stress in mice

To explore the correlation between the expression of brain-derived neurotrophic factor (BDNF) and vascular endothelial growth factor (VEGF) in the hippocampus and forebrain of mice and depression caused by chronic stress...

2021-08-05
【Animal Modeling】-Comparison Study of Small Animal Micro-CT, Ultrasound and Aortic Intubation in the Evaluation of Left Ventricular Function

【Animal Modeling】-Comparison Study of Small Animal Micro-CT, Ultrasound and Aortic Intubation in the Evaluation of Left Ventricular Function

To study the consistency and correlation of micro-CT, aortic cannulation, and echocardiography in the measurement of left ventricular function parameters, and to evaluate the value of micro-CT in the evaluation of left ventricular function...

2021-08-05
【Animal Modeling】-Isoproterenol-induced changes in the pathological tissue of myocardial cells caused by specific myocardial ischemia in rats

【Animal Modeling】-Isoproterenol-induced changes in the pathological tissue of myocardial cells caused by specific myocardial ischemia in rats

By observing the expression of HE staining in myocardial tissue slices caused by subcutaneous injection of isoproterenol for different days (1 mg/kg body weight), VEGF (vascular endothelial growth factor) and FCF (fibroblast growth factor) caused spe...

2021-08-05
【Animal Modeling】-The application of lactose-free milk powder with deep hydrolyzed protein in the cultivation of sterile rats

【Animal Modeling】-The application of lactose-free milk powder with deep hydrolyzed protein in the cultivation of sterile rats

In the cultivation of sterile rats, the artificially prepared milk after birth is very important for the cultivation of sterile rats...

2021-08-05
Animal experiments reveal the inner mechanism of human hallucinations

Animal experiments reveal the inner mechanism of human hallucinations

According to new research, when our brain wants to believe something beyond a certain limit, it will have hallucinations. This may happen to everyone occasionally, but in extreme cases, hallucinations are a symptom of a serious mental illness...

2021-08-04
【Animal Modeling】-Animal experimental study of two different types of left atrial appendage occluders

【Animal Modeling】-Animal experimental study of two different types of left atrial appendage occluders

To evaluate the feasibility and safety of two different left atrial appendage occluders (single-disc cylindrical type and double-disc split type) for blocking the left atrial appendage of the target animal...

2021-08-04
【Animal Modeling】-Leptin receptor knockout causes activation of rat brain microglia

【Animal Modeling】-Leptin receptor knockout causes activation of rat brain microglia

This article uses leptine receptor (LEPR) gene knockout rats to analyze the changes in the morphology and function of microglia in the rat brain after the leptine receptor gene is knocked out, and to explore the leptin receptor in microglia. The role...

2021-08-04
[Animal Modeling]-Effect of Tongxinluo Capsule on Inflammatory Response, Brain Edema and Cognitive Function after Exposure to Low Pressure and Hypoxia in Rats

[Animal Modeling]-Effect of Tongxinluo Capsule on Inflammatory Response, Brain Edema and Cognitive Function after Exposure to Low Pressure and Hypoxia in Rats

To explore the neuroprotective effects and related mechanisms of Tongxinluo Capsules on cognitive impairment in rats with acute hypoxia...

2021-08-04
【Animal Modeling】-Paeoniflorin improves Bayk8644-induced depression and anxiety-like behavior in rats and its mechanism

【Animal Modeling】-Paeoniflorin improves Bayk8644-induced depression and anxiety-like behavior in rats and its mechanism

To study the pharmacological mechanism of paeoniflorin in improving depression and anxiety-like behaviors in rats based on L-type voltage-gated calcium channels...

2021-08-04
[Animal Modeling]-Study on the mechanism of anterior cingulate cortex of different time electroacupuncture intervention on anxiety behavior in rats with pain aversion

[Animal Modeling]-Study on the mechanism of anterior cingulate cortex of different time electroacupuncture intervention on anxiety behavior in rats with pain aversion

To explore the palliative effect of electroacupuncture on the anxiety behavior of pain-averse rats and its influence on N-methyl-D-aspartic acid (NMDA) and γ-aminobutyric acid (GABA) receptors in the anterior cingulate cortex (ACC)...

2021-08-04
【Animal Modeling】-Effects of Electroacupuncture on Synaptic Plasticity and Microglia Polarization in Rats with Cerebral Ischemia

【Animal Modeling】-Effects of Electroacupuncture on Synaptic Plasticity and Microglia Polarization in Rats with Cerebral Ischemia

To study the synaptic plasticity and microglia polarization of electroacupuncture in rats with focal cerebral ischemia, and to detect the expression of miR-21/signal transducer and activator of transcription 3 (STAT3) pathway...

2021-08-04