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【Animal Modeling】-Establishment and identification of paclitaxel-resistant lung transplanted tumor model in orthotopic mice

【Animal Modeling】-Establishment and identification of paclitaxel-resistant lung transplanted tumor model in orthotopic mice

To establish an animal model of orthotopic lung transplantation for paclitaxel-resistant tumors to study the mechanism of drug resistance...

2021-07-28
【Animal Modeling】-Establishment of a rat model of chronic hyperuricemia with renal damage

【Animal Modeling】-Establishment of a rat model of chronic hyperuricemia with renal damage

Establish a rat model of chronic hyperuricemia nephropathy, and provide model tools for the development of anti-chronic hyperuricemia nephropathy drugs...

2021-07-28
【Animal Modeling】-Preliminary establishment of rat transplantation model of human glioma

【Animal Modeling】-Preliminary establishment of rat transplantation model of human glioma

It is the first time to establish a rat xenograft model of human glioma using immunosuppressive agents, providing an ideal experimental tool for clinical and basic research...

2021-07-28
【Animal modeling】-CD32 expression characteristics in a rhesus monkey model of latent AIDS infection

【Animal modeling】-CD32 expression characteristics in a rhesus monkey model of latent AIDS infection

Establish a latent infection model of Rhesus monkey SIVmac239, study the expression characteristics of CD32 in resting, activated and/or memory CD4+ T cell subsets, and analyze its potential as a marker of AIDS latent pool...

2021-07-28
[Animal Modeling]-The mechanism of miR-20a-5p regulating VEGF pathway in a mouse model of oxygen-induced retinopathy

[Animal Modeling]-The mechanism of miR-20a-5p regulating VEGF pathway in a mouse model of oxygen-induced retinopathy

Explore the mechanism of microRNA (miR)-20a-5p regulating the vascular endothelial growth factor (VEGF) pathway of oxygen-induced retinopathy (OIR) in mice...

2021-07-28
【Animal Modeling】-Research Progress of Hollow Fiber Tumor Model

【Animal Modeling】-Research Progress of Hollow Fiber Tumor Model

The hollow fiber tumor model or HollowFiberAssay (HFA) is a new type of anti-cancer drug pre-screening model designed by the National Cancer Institute (NCI), which is simple, fast, accurate, simple and feasible....

2021-07-28
【Animal Modeling】-Analysis of the application of 274 rheumatoid arthritis animal models based on data mining

【Animal Modeling】-Analysis of the application of 274 rheumatoid arthritis animal models based on data mining

Study the modeling elements of animal models of rheumatoid arthritis, improve the success rate of modeling, and provide methodological references for evaluating the efficacy of tested drugs...

2021-07-28
【Animal Modeling】-A new mouse model of severe heart disease in children

【Animal Modeling】-A new mouse model of severe heart disease in children

Severe childhood restrictive cardiomyopathy is a condition in which the muscles of the myocardial wall become stiff and prevent the heart from filling up with blood normally....

2021-07-28
【Animal Modeling】-Establish an animal model of human intestinal flora of Alzheimer\'s disease

【Animal Modeling】-Establish an animal model of human intestinal flora of Alzheimer's disease

Fecal bacterial transplantation was used to obtain human intestinal flora of Alzheimer\'s disease model mice through oral route, and the model was evaluated through bioinformatics, histopathology and other methods...

2021-07-28
【Animal Modeling】-Establishment of a mouse model of chronic thrombosis induced by carrageenan

【Animal Modeling】-Establishment of a mouse model of chronic thrombosis induced by carrageenan

The mice were treated by continuous intraperitoneal injection of different concentrations of carrageenan solution, and the disease condition of the mouse model of chronic thrombosis was screened....

2021-07-28
【Animal Modeling】-Establishment of a rat model of coronary heart disease combined with Qi deficiency and blood stasis syndrome

【Animal Modeling】-Establishment of a rat model of coronary heart disease combined with Qi deficiency and blood stasis syndrome

Establish a compound model of the relationship between pathology, etiology, coronary heart disease (CHD) Qi deficiency and blood stasis syndrome combined with tongue symptoms and the relationship between prostacyclin (PGI2) and thromboxane A2 (TXA2)...

2021-07-27
【Animal Modeling】-Ovalbumin (OVA) sensitization combined with smoking method to establish cough variant asthma guinea pig model

【Animal Modeling】-Ovalbumin (OVA) sensitization combined with smoking method to establish cough variant asthma guinea pig model

Try to use ovalbumin in combination with smoking to establish a more similar guinea pig CVA model...

2021-07-27
【Animal Modeling】-Experimental study of SD rat portal hypertension animal model prepared by ligation of the left branch

【Animal Modeling】-Experimental study of SD rat portal hypertension animal model prepared by ligation of the left branch

To explore whether a simple ligation of the left portal vein can form a stable portal hypertension, and whether nitric oxide plays a corresponding role...

2021-07-27
【Animal Modeling】-STZ Research Progress on the Influencing Factors of Diabetic Rat Models

【Animal Modeling】-STZ Research Progress on the Influencing Factors of Diabetic Rat Models

Diabetes has become a worldwide epidemic, and its incidence is increasing year by year. In order to further study the causes of DM and formulate more effective prevention and treatment plans, researchers need a stable and reproducible animal model si...

2021-07-27
【Animal Modeling】-Research progress on the establishment of preeclampsia rat mouse model

【Animal Modeling】-Research progress on the establishment of preeclampsia rat mouse model

Pre-eclampsia (PE) is a unique pregnancy disease and one of the main causes of morbidity and death in pregnant women and perinatal infants...

2021-07-27
【Animal Modeling】-Establishment and applicability evaluation of animal model of pelvic organ prolapse

【Animal Modeling】-Establishment and applicability evaluation of animal model of pelvic organ prolapse

Establish a rat animal model that can reflect the similar pathological changes of the sacral ligament in patients with pelvic organ prolapse, and explore the effects of increased labor intensity and simulated menopause on the pathological changes of ...

2021-07-27