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【Animal Modeling】-Research progress on the role of T cell subsets in ventricular remodeling

【Animal Modeling】-Research progress on the role of T cell subsets in ventricular remodeling

Cardiovascular disease is one of the leading causes of death in the world. According to the World Health Organization, approximately 20 million people died of cardiovascular disease in 2015, and it will continue to be the leading cause of death in th...

2021-07-21
【Animal Modeling】-Pine pollen assisted paclitaxel combined with platinum-based chemotherapy to increase efficacy and reduce toxicity

【Animal Modeling】-Pine pollen assisted paclitaxel combined with platinum-based chemotherapy to increase efficacy and reduce toxicity

To study whether pine pollen has inhibitory and synergistic effects on paclitaxel combined with platinum chemotherapy...

2021-07-21
【Animal Modeling】-The effect of vanadium exposure on the inflammatory response and migration of rat microglia

【Animal Modeling】-The effect of vanadium exposure on the inflammatory response and migration of rat microglia

Observe the effect of sodium metavanadate (NaVO3-2H2O) exposure on the inflammatory response and migration of microglia, and explore the related mechanisms of vanadium neurotoxicity...

2021-07-21
【Animal Modeling】-Comparison of the difference between single staining and counter staining in observing the osteoarthritis slices of SIRT1 knockout mice

【Animal Modeling】-Comparison of the difference between single staining and counter staining in observing the osteoarthritis slices of SIRT1 knockout mice

A related mouse osteoarthritis model was established by SIRT1 gene knockout, and on the basis of this model, the differences in cartilage tissue slice morphology were observed through various single or combined staining techniques...

2021-07-21
[Animal modeling]-Flow cytometry analysis of the phenotypic characteristics of PMA-induced THP-1 differentiation into macrophages

[Animal modeling]-Flow cytometry analysis of the phenotypic characteristics of PMA-induced THP-1 differentiation into macrophages

Using flow cytometry, it was revealed that THP-1 cells were only differentiated by PMA-induced macrophages...

2021-07-21
[Animal Modeling]-Scientists use gene editing technology to eliminate viruses in live pigs

[Animal Modeling]-Scientists use gene editing technology to eliminate viruses in live pigs

Scientists edit the pig genome to inactivate a family of retroviruses. These results have important implications for human transplantation medicine...

2021-07-20
【Animal Modeling】-DB11/T828.3-2011 Chromosome 12 Marker Screening and Applicability Evaluation Research

【Animal Modeling】-DB11/T828.3-2011 Chromosome 12 Marker Screening and Applicability Evaluation Research

By screening the missing chromosome 12 markers in the local standard DB11/T828.3-2011, comparing different markers for genetic evaluation of the same population of miniature pigs in Beijing area, and analyzing the applicability of landmarks...

2021-07-20
【Animal Modeling】-High-throughput sequencing method to study the effect of different pH drinking water on the gut microbes of SPF mice

【Animal Modeling】-High-throughput sequencing method to study the effect of different pH drinking water on the gut microbes of SPF mice

To study the effect of drinking water with different pH values on the intestinal microbial diversity of SPF mice...

2021-07-20
[Animal Modeling]-Preparation of rat thoracic aorta vascular smooth muscle cells by an improved two-step compound enzyme digestion method

[Animal Modeling]-Preparation of rat thoracic aorta vascular smooth muscle cells by an improved two-step compound enzyme digestion method

This article reports an improved method for isolating rat thoracic aortic vascular smooth muscle cells based on complex enzyme digestion....

2021-07-20
【Animal Modeling】-Hydrogen-rich liquid reduces cerebral ischemia-reperfusion injury in rats through PI3K pathway

【Animal Modeling】-Hydrogen-rich liquid reduces cerebral ischemia-reperfusion injury in rats through PI3K pathway

To investigate the effect of hydrogen-rich liquid on hippocampal neuron apoptosis and PI3K/Akt/FoxO1 signal pathway expression induced by cerebral ischemia-reperfusion in rats...

2021-07-20
【Animal Modeling】-Comparison of the effect of calcium chelated collagen peptide and estrogen on the bone quality of ovariectomized rats

【Animal Modeling】-Comparison of the effect of calcium chelated collagen peptide and estrogen on the bone quality of ovariectomized rats

To compare the bone-improving effects of calcium chelated collagen polypeptide (CPCC) and estrogen, and lay the foundation for the development of safe osteoporosis (OP) prevention and treatment drugs...

2021-07-20
【Animal Modeling】-Deoxyvioletin inhibits the proliferation of colon cancer TH29 cells and induces apoptosis and its mechanism

【Animal Modeling】-Deoxyvioletin inhibits the proliferation of colon cancer TH29 cells and induces apoptosis and its mechanism

To investigate the inhibitory effect of deoxyionization on the proliferation and inducing apoptosis of human colon cancer HT29 cells and its possible mechanism...

2021-07-20
【Animal Modeling】-Guanxinning Tablet Protects Myocardial Ischemia-Reperfusion Injury

【Animal Modeling】-Guanxinning Tablet Protects Myocardial Ischemia-Reperfusion Injury

To observe the effects of Guanxinning tablets (GXNT) on myocardial infarction and cardiac autonomic nerve function in rats with myocardial ischemia reperfusion injury (MI/RI)...

2021-07-20
【Animal Modeling】-The effect of bacitrin on experimental autoimmune encephalomyelitis in mice

【Animal Modeling】-The effect of bacitrin on experimental autoimmune encephalomyelitis in mice

Observe the effects of different concentrations of baicalin on experimental autoimmune encephalomyelitis mouse models, and preliminarily explore its mechanism of action...

2021-07-19
【Animal Modeling】-The effect of self-made Gehua Jiejiu Dizhi Decoction on liver fat deposition and PXR expression in alcoholic fatty liver mice

【Animal Modeling】-The effect of self-made Gehua Jiejiu Dizhi Decoction on liver fat deposition and PXR expression in alcoholic fatty liver mice

Understand the effect of homemade Gehua Jiejiu Dizhi Decoction on liver fat deposition in alcoholic fatty liver (AFLD) mice, and observe its effect on liver tissue pregnane receptor (PXR) and its regulatory target genes CYP3A11 and CYP3A25 protein mR...

2021-07-19
【Animal Modeling】-Sequential Observation of Acute Kidney Injury Induced by Cisplatin in Rabbits

【Animal Modeling】-Sequential Observation of Acute Kidney Injury Induced by Cisplatin in Rabbits

To explore the course of acute kidney injury (AKI) in rabbits caused by a single intravenous injection of cisplatin...

2021-07-19