[Animal Modeling]-Changes of blood biochemical index levels in rats with chronic alcoholic liver injury after transplantation of human amniotic membrane mesenchymal stem cells

Studies have shown that human amniotic membrane mesenchymal stem cells have a variety of differentiation and proliferation functions, induce differentiation into liver-like cells, thereby resisting liver damage...

2021-07-19

【Animal Modeling】-Pharmacokinetics Study of Granisetron Hydrochloride Transdermal Patch in Beagle Dogs with Multi-dose Administration

Establish a method to determine the blood concentration of Beagle dog granisetron transdermal patch, clarify the pharmacokinetic changes of Beagle dog granisetron transdermal patch after multiple administrations, provide dynamic characteristics and I...

2021-07-19

【Animal Modeling】-DS-1226 Improves Depressive Behavior of Mice Caused by Chronic Sleep Disturbance

To study the antidepressant effect of ginsenoside hydrolysate DS-1226 on mice with chronic sleep disorders, and provide a scientific basis for the development of antidepressants...

2021-07-19

【Animal Modeling】-Study on the mechanism of trace element strontium in improving non-alcoholic fatty liver in rats

To explore the mechanism of the trace element strontium in improving non-alcoholic fatty liver in rats...

2021-07-19

【Animal Modeling】-The effect of neural stem cell-specific LSD1 gene knockout on mood and memory in mice

By conditionally knocking out the LSD1 gene in mouse neural stem cells, observe the proliferation of mouse nerve cells and mouse behavior, and clarify the neurobiological function of LSD1...

2021-07-19

【Animal Modeling】-The effect of androgen deficiency on visceral fat accumulation and inflammatory gene expression in miniature pigs under high-fat environment

To study the effects of androgen deficiency on visceral fat deposition, serum hormones and inflammation-related gene expression in miniature pigs in a high-fat environment...

2021-07-19

【Animal Modeling】-The influence of Labrador Retriever’s behavior and heart rate changes on the success rate of guide dog training in distance test

Use the distance test (DT) to evaluate the behavior and heart rate characteristics of Labrador dogs, and provide effective behavioral methods and physiological basis for the pre-screening of guide dogs...

2021-07-19

【Animal Modeling】-Targeted inhibition of Act1 expression of macrophages on ulcerative colitis

Explore the role of macrophage NF-κB activator 1 (nuclearfactorkappaBactivator1, Act1) in inflammatory bowel disease...

2021-07-16

[Animal modeling]-Hba-α protein distribution and differential expression of hatched blastocysts and dormant embryos in mice before and after programmed freezing

To study the distribution and differential expression of Hba-α protein in mouse hatching blastocysts and dormant embryos before and after freezing, and to explore the future development and development of new mammalian antifreeze proteins to provide ...

2021-07-16

【Animal Modeling】-Effects of Bushen and Ovulation Decoction on Ovarian Morphology and Sex Hormones in Rats with Polycystic Ovary Syndrome

Observe the effects of sex hormones, anti-Müllerian hormone (AMH), Bushen Fufang Ovulation Decoction on ovarian morphology in rats with polycystic ovary syndrome, and observe the mechanism of Bushen Fufang Ovulation Decoction (Polycystic Ovary Syndro...

2021-07-16

The role of stromal cell-derived factor-1 and chemokine receptor 4 in the rejection of rat corneal transplantation

To investigate the expression of stromal cell-derived factor-1 (SDF-1) and stromal cell-derived factor-1 (CXCR4) in rat corneal tissues and their role in immune rejection after corneal transplantation...

2021-07-16

【Animal Modeling】-Comparative study of two puncture methods of rabbit hepatic artery cannulation

Explore the way and method of experimental rabbit hepatic artery cannulation...

2021-07-16

[Animal Modeling]-Preliminary Study on the Mechanism of Hypoxic Preconditioning to Reduce the Susceptibility of Rats to Epilepsy and Its Brain Protection

To investigate the effect of intermittent hypoxic preconditioning (IHP) on lithium pilocarpine (Li-pilo)-induced seizures and its brain protection mechanism...

2021-07-16

[Animal modeling]-Protective effect of ginseng coenzyme Q10 sunscreen on mice damaged by ultraviolet rays

Study the protective effect of sunscreen coenzyme Q10 on mice...

2021-07-16

【Animal Modeling】-The effect of long-term consumption of Polygonum multiflorum on hematopoietic system in mice

To study the changes of hematopoietic system in mice after long-term ingestion of Polygonum multiflorum...

2021-07-16

【Animal Modeling】-The effect of benzene pollution on rat liver and kidney function and blood nucleotide level

To study the effects of benzene on liver and kidney function and blood nucleotide levels in Wistar rats...

2021-07-16