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Touch the intercostal space where the apex of the rat is most pulsating, cut the skin and intercostal muscles, squeeze out the heart, find the anterior descending branch at the junction of the pulmonary artery cone and the left atrial appendage, liga...
2020-08-12Latent membrane protein (LMP): including LMP-1, 2A, 28. LMP-1 gene is currently the only confirmed EB virus malignant transformation gene. EBV-related animal models There are not many EBV-related animal models established so far, and they mainly focu...
2020-08-12Use specially bred small pigs for experimental use. For chronic experiments, it is best to choose piglets weighing 25-30kg and about 6 months old to ensure the convenience of the operation and the weight increase at the end of the study....
2020-08-12The selection and preparation of animals is the key to the success of the model preparation. For mature pathogenic animal models, the type of animal and the level of microorganisms have been clarified and should be prepared strictly in accordance wit...
2020-08-12The rupture of atherosclerotic plaques in the coronary arteries and the accompanying arterial thrombosis is the final end point of the long and complicated pathophysiological process of atherosclerosis, which is difficult to perform in humans in any ...
2020-08-12Temperature-sensitive L cell mutant mouse model: Thompson (1971) isolated two temperature-sensitive mouse mutant L cells tsA1S9 and tsC1. Cytological studies have shown that these two ts cell mutations are responsible for similar morphological change...
2020-08-12In previous studies, models of myocardial infarction have been established in various experimental animals. When small animals can be selected according to the requirements of the research, mice are the best choice. On the one hand, the cost of buy...
2020-08-12Sex-related hereditary anemia mice, the gene symbol sla is a recessive recessive related to the sex of the X chromosome...
2020-08-12The replication method mainly uses gene knockout to create animal models...
2020-08-12Therapeutic angiogenesis has become one of the hotspots of coronary heart disease research since the 1990s...
2020-08-12BALB/c mice, placed in an environment containing 5 mg of chloroform per liter of air, for 3 hours, can cause kidney necrosis in varying degrees...
2020-08-12Animal selection Choose healthy Japanese white rabbits or New Zealand rabbits, both male and female...
2020-08-12Construction of a nervous system stellate cell-specific expression vector containing the human herpes virus 6BU83 gene, and after microinjection into mouse fertilized egg cells, a transgenic mouse line expressing human herpes virus 6BU83 was establis...
2020-08-12200～300g male rats (no proteinuria measured before surgery), after anesthesia, incision on the left side of the abdomen to expose the left side, peel off the renal fascia, and put a cold knife (1.2cm×0.8cm× 15cm)...
2020-08-12The long terminal repeat (LTR) of HW-1 is linked to the indicator gene in transgenic mice, that is, the LTTR gene is linked to the indicator gene-chloramphenin acetyltransferase (CAT) and then introduced into mouse cells...
2020-08-121. Modeling material animal: SD rat, female, 2 to 3 months old, weighing 180 to 220g; drug: 6-hydroxydopamine (6-OHDA), apomorphine, rabbit anti-tyrosine hydroxyl Enzyme serum, avidin-biotin-peroxidase complex (ABC) kit; equipment: rat brain stereota...
2020-08-12