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【Animal Modeling】-Prophylactic administration of all-trans retinoic acid can relieve rheumatoid arthritis model

【Animal Modeling】-Prophylactic administration of all-trans retinoic acid can relieve rheumatoid arthritis model

Explore the effects of all-trans retinoic acid (ATRA) on type II collagen (CII)-induced rheumatoid arthritis (CIA) rat arthritis formation stage joint tissue structure, serum expression of related inflammatory cytokines, and cartilage damage Influenc...

2023-01-31
【Animal Modeling】-How to establish a nude mouse myeloid leukemia model?

【Animal Modeling】-How to establish a nude mouse myeloid leukemia model?

Use BALB/c nude mice to establish M1 leukemia model?...

2023-01-30
【Animal Modeling】-Ovalbumin (OVA) sensitization combined with smoking method to establish cough variant asthma guinea pig model

【Animal Modeling】-Ovalbumin (OVA) sensitization combined with smoking method to establish cough variant asthma guinea pig model

Try to use ovalbumin in combination with smoking to establish a more similar guinea pig CVA model...

2023-01-30
【Animal modeling】-Effect of baicalin on experimental autoimmune encephalomyelitis mice

【Animal modeling】-Effect of baicalin on experimental autoimmune encephalomyelitis mice

To observe the effect of different concentrations of baicalin (baicalin) on experimental autoimmune encephalomyelitis mouse model, and to study its preliminary mechanism...

2023-01-30
【Animal modeling】-Intervention effect of electroacupuncture on NF-κBp65 protein in the spinal dorsal horn of rats with diabetic neuralgia

【Animal modeling】-Intervention effect of electroacupuncture on NF-κBp65 protein in the spinal dorsal horn of rats with diabetic neuralgia

To observe the intervention effect of electroacupuncture on the nuclear transcription factor κBp65 protein in the spinal dorsal horn of rats with diabetic neuralgia, so as to explore the partial analgesic mechanism of electroacupuncture in diabetic n...

2023-01-29
【Animal Modeling】-The regulatory mechanism of peripheral pain sensation in rats based on the interaction of TRPV1 and P2X3

【Animal Modeling】-The regulatory mechanism of peripheral pain sensation in rats based on the interaction of TRPV1 and P2X3

To observe the relationship between peripheral TRPV1 and P2X3 in rats, in order to partially elucidate the regulatory mechanism of peripheral pain sensation...

2023-01-29
【Animal Modeling】-Comparison of single staining and counterstaining in the observation of osteoarthritis sections of SIRT1 knockout mice

【Animal Modeling】-Comparison of single staining and counterstaining in the observation of osteoarthritis sections of SIRT1 knockout mice

To establish a related mouse knee osteoarthritis model by knocking out SIRT1 gene, and to observe the differences in the morphology of cartilage tissue sections with different single staining or compound staining techniques...

2023-01-29
【Animal Modeling】-Effect of ovariectomy on skin aging in osteoporotic rats

【Animal Modeling】-Effect of ovariectomy on skin aging in osteoporotic rats

Osteoporosis model constructed with ovariectomized rats is the most suitable model to study postmenopausal osteoporotic disease, however, the effect on skin after ovary removal in rats is seldom studied....

2023-01-29
Research on spinal muscular atrophy achieves breakthrough through animal modeling technology

Research on spinal muscular atrophy achieves breakthrough through animal modeling technology

A few days ago, the Institute of Neuroscience of Soochow University and Professor Hua Yimin of Cold Spring Harbor Laboratory in the United States developed a number of mouse disease models, which effectively increased the expression of motor neuron s...

2023-01-18
[Animal modeling]-Infectious SIV exists in the fatty tissue of chronically infected rhesus monkeys and causes metabolic defects

[Animal modeling]-Infectious SIV exists in the fatty tissue of chronically infected rhesus monkeys and causes metabolic defects

Memory CD4 T cells and macrophages are the main host and cell bank of humans and HIV in non-human primates...

2023-01-18
【Animal Modeling】-Hydrogen-rich liquid attenuates cerebral ischemia-reperfusion injury in rats through PI3K pathway

【Animal Modeling】-Hydrogen-rich liquid attenuates cerebral ischemia-reperfusion injury in rats through PI3K pathway

To investigate the effect of hydrogen-rich solution on the apoptosis of hippocampal neurons and the expression of PI3K/Akt/FoxO1 signaling pathway induced by cerebral ischemia-reperfusion in rats...

2023-01-18
【Animal Modeling】-The effect of metformin and aerobic exercise on vascular oxidative stress in type 2 diabetic rats

【Animal Modeling】-The effect of metformin and aerobic exercise on vascular oxidative stress in type 2 diabetic rats

How to evaluate the effects of aerobic exercise and metformin combined with aerobic exercise on vascular oxidative stress in type 2 diabetic rats?...

2023-01-18
【Animal Modeling】-Applying TaqMan probe fluorescence quantitative PCR technology to identify the genotypes of Leprdb/+ mouse progeny

【Animal Modeling】-Applying TaqMan probe fluorescence quantitative PCR technology to identify the genotypes of Leprdb/+ mouse progeny

How to establish an effective method for genotyping Leprdb/+ mouse offspring using TaqMan probe fluorescence quantitative PCR technology...

2023-01-18
【Animal Modeling】-Methodological Research on Establishing Mouse Model of Learning and Memory Impairment

【Animal Modeling】-Methodological Research on Establishing Mouse Model of Learning and Memory Impairment

To study effective methods to avoid darkness and Morris water maze experiment to establish a model of learning and memory impairment in mice...

2023-01-18
【Animal Modeling】-New Model of Colon Cancer

【Animal Modeling】-New Model of Colon Cancer

MIT researchers showed in mice that a gene editing system called CRISPR can be used to generate colon tumors that are very similar to human tumors...

2023-01-18
【Animal Modeling】-Mixed Memory Disorder Model

【Animal Modeling】-Mixed Memory Disorder Model

反复脑缺血再灌法建立学习记忆障碍模型...

2023-01-18