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Using CRISPR/Cas9 technology, targeted knockout of Rag2 gene encoding mouse T cells and B cells and IL2rg gene encoding NK cells to construct immunodeficient mice that combine T, B, and NK cells...
2021-06-21Rats are one of the most commonly used model animals in life science research...
2021-06-21Establish background data of SPF-grade congenital cataract mice body weight, main organ weight, and blood physiological and biochemical indicators...
2021-06-21Hemophilic arthropathy is a debilitating disease caused by spontaneous intra-articular hemorrhage and recurrent intra-articular hematoma. The main clinical manifestations are chronic pain, joint damage and poor quality of life....
2021-06-21Maternal separation (MS) has always been a classic animal model for studying the neurobiological mechanism of the adverse effects of early stress on individual physiology and psychology, and is an important early social deprivation...
2021-06-21
Researchers have now discovered that genetic mutations associated with an increased risk of eating disorders in humans cause many behavioral disorders in mice that are very similar to those in patients with anorexia nervosa...
2021-06-18This article will summarize various research ideas and establish a comprehensive animal model of diseases through the establishment of animal models of modern medicine, the establishment of animal models of TCM syndromes, and the establishment of ani...
2021-06-18As the global prevalence of metabolic syndrome continues to rise, the prevalence of non-alcoholic fatty liver (NAFLD) is also rising. NAFLD, including simple fatty liver and non-alcoholic steatohepatitis, has become the most common chronic liver dise...
2021-06-18Intrauterine infection can invade the uterine cavity of pregnancy through various pathogens, and have adverse effects on mothers and babies, such as abnormal pregnancy, neonatal diseases, etc., but the cause is unknown, so the treatment effect is poo...
2021-06-17Explore an ideal method to establish a rat skull defect model and increase the success rate of animal models of bone defect...
2021-06-17To explore whether simple ligation of the left portal vein can form stable portal hypertension, and whether nitric oxide plays a corresponding role...
2021-06-16Crohn’s disease is a chronic inflammatory bowel disease, and its etiology has always been a hot and difficult point in medical research....
2021-06-16Primary headache is one of the diseases with a high disability rate, which mostly occurs in young and middle-aged people...
2021-06-16Diabetes (DM) has become a worldwide epidemic, and the incidence is increasing year by year. In order to further study the causes of DM and formulate more effective prevention and treatment plans, researchers need a stable and reproducible animal mod...
2021-06-16Evaluation of the advantages and disadvantages of the three surgical models of extrahepatic cholestasis in rats by serology, imaging and pathology...
2021-06-16Observe the therapeutic effect of electroacupuncture at \"Zusanli\" and \"Kunlun\" points on mechanical hyperalgesia in a complex local pain syndrome type I rat model, and observe the therapeutic effect of electroacupuncture on CR...
2021-06-16