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【Animal Modeling】-Clamping the tail somatosensory stimulus inhibits the excitability of pyramidal neurons in the CA1 region of the hippocampus of rats

【Animal Modeling】-Clamping the tail somatosensory stimulus inhibits the excitability of pyramidal neurons in the CA1 region of the hippocampus of rats

The team of Dr. Feng Zhouyan from Zhejiang University in China used a microelectrode array to monitor the activity of neurons in the hippocampus of rats and found that the felt stimulus of the tail clip can induce different types of neurons to produc...

2021-10-18
【Animal Modeling】-Xiamen University uses CRISPR/Cas9 system to efficiently edit the Plasmodium genome

【Animal Modeling】-Xiamen University uses CRISPR/Cas9 system to efficiently edit the Plasmodium genome

The research group of Professor Yuan Jing from the School of Life Sciences, Xiamen University applied the CRISPR/Cas9 system to efficiently complete different types of modifications of multiple genes in the Plasmodium genome, including gene deletion,...

2021-10-18
【Animal Modeling】-Successful animal experiment of gene therapy for hemophilia

【Animal Modeling】-Successful animal experiment of gene therapy for hemophilia

Hemophilia is a disease caused by hereditary coagulation disorders. It is characterized by the human body’s inability to produce coagulation factors or lack of coagulation factor production, resulting in prolonged clotting time and difficult to stop ...

2021-10-18
[Animal Modeling]-Camouflage technology inspired by the skin cells of cephalopods

[Animal Modeling]-Camouflage technology inspired by the skin cells of cephalopods

A study found that the separation of a temperature-sensitive dye on a thin flexible electrical substrate from a diffused light sensor can bring a system capable of automatically adapting and matching the colors of their surroundings, as a kind of bio...

2021-10-18
Through the method of genetic selection of nematodes, the early work of Zhang Hong’s research group from the Institute of Biophysics of the Chinese Academy of Sciences found that the epg-6 gene is an

Through the method of genetic selection of nematodes, the early work of Zhang Hong’s research group from the Institute of Biophysics of the Chinese Academy of Sciences found that the epg-6 gene is an

Through the method of genetic selection of nematodes, the early work of Zhang Hong’s research group from the Institute of Biophysics of the Chinese Academy of Sciences found that the epg-6 gene is an important autophagy gene unique to multicellular o...

2021-10-18
[Animal modeling]-Excitatory neuron precursors exhibit tangential migration in the brains of adult mammals

[Animal modeling]-Excitatory neuron precursors exhibit tangential migration in the brains of adult mammals

The development of the mammalian brain is a complex and orderly process that is highly accurately regulated. After a long period of research and discussion, scientists once had a certain understanding of brain development and established some fundame...

2021-10-18
【Animal Modeling】-The protective effect of Jiedu Quyu Zishen Decoction on the kidney of MRL/lpr lupus mice interfered with TLR9 signaling pathway

【Animal Modeling】-The protective effect of Jiedu Quyu Zishen Decoction on the kidney of MRL/lpr lupus mice interfered with TLR9 signaling pathway

Based on the intervention of TLR9-MyD88-NF-κB pathway, explain the maintenance effect of Jiedu Quyu Zishen Recipe on the kidney of lupus rats...

2021-10-18
【Animal Modeling】-Yuemaijia Banxia Decoction reduces serum IgE in mice with allergic asthma and increases the activity of SOD in lung tissues

【Animal Modeling】-Yuemaijia Banxia Decoction reduces serum IgE in mice with allergic asthma and increases the activity of SOD in lung tissues

After observing the changes in the vitality and inhibition rate of immunoglobulin (IgE) in serum and superoxide dismutase (SOD) in lung tissue of mice in different stages of each experimental group, to discuss the effects of Yuemaijia Banxia Decoctio...

2021-10-18
[Animal modeling]-Changes and significance of oxidative stress and cytokines in the formation of non-alcoholic fatty liver disease in gerbils

[Animal modeling]-Changes and significance of oxidative stress and cytokines in the formation of non-alcoholic fatty liver disease in gerbils

To study the dynamic changes and significance of oxidative stress and cytokines in the composition of non-alcoholic fatty liver disease (NAFLD) in gerbils...

2021-10-18
【Animal Modeling】-Comparison of the four test results of SD rats with two different reagents

【Animal Modeling】-Comparison of the four test results of SD rats with two different reagents

Compare the test results of the four blood coagulation tests (PT, APTT, TT, FIB) of experimental animal SD rats and human blood coagulation reagents of two different brands of imported and domestic manufacturers to see if there is a difference betwee...

2021-10-18
[Animal Modeling]-The combined effect of estrogen and androgen on the blood lipid level and coagulation function of hyperlipidemia mice

[Animal Modeling]-The combined effect of estrogen and androgen on the blood lipid level and coagulation function of hyperlipidemia mice

To discuss the effect of the combination of estrogen and androgen on the blood lipid level and coagulation function of hyperlipidemia mice...

2021-10-18
【Animal Modeling】-The influence of insufficient blood volume of SD mouse on the four test results of coagulation

【Animal Modeling】-The influence of insufficient blood volume of SD mouse on the four test results of coagulation

To explore the best anticoagulation ratio in rats and analyze the influence of insufficient blood volume of specimens on the four test results of coagulation...

2021-10-18
[Animal Modeling]-Research on the lowering of blood glucose in type 2 diabetic mice by a vaccine targeting RBP-4

[Animal Modeling]-Research on the lowering of blood glucose in type 2 diabetic mice by a vaccine targeting RBP-4

To discuss the effectiveness and feasibility of vaccine immune intervention against insulin resistance with human RBP-4 as the target, and to provide basic research data for the advancement of new treatments for type 2 diabetes...

2021-10-18
【Animal Modeling】-The effect of morroniside on the expression of TIMP in the cortex of ischemia-reperfusion rats

【Animal Modeling】-The effect of morroniside on the expression of TIMP in the cortex of ischemia-reperfusion rats

To study the effect of morroniside on the expression of tissue inhibitor of metalloproteinase (TIMP) in rat cortex after 7 days of ischemia-reperfusion...

2021-10-15
【Animal Modeling】-IGF-1 gene and electric stimulation treatment affect the rat model of postpartum stress urinary incontinence

【Animal Modeling】-IGF-1 gene and electric stimulation treatment affect the rat model of postpartum stress urinary incontinence

Discuss the effect of IGF-1 gene therapy on the rat model of postpartum stress urinary incontinence, and explore the ideal treatment for the disease...

2021-10-15
【Animal Modeling】-The effect of alcohol extract of two-color coreopsis on the intestinal flora of type 2 diabetic mice

【Animal Modeling】-The effect of alcohol extract of two-color coreopsis on the intestinal flora of type 2 diabetic mice

Explore the possible link between two-color coreopsis alcohol extract, intestinal flora and type 2 diabetes (T2DM)...

2021-10-15