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How to establish a mouse model of preeclampsia in rats? -【Animal Modeling】

How to establish a mouse model of preeclampsia in rats? -【Animal Modeling】

Pre-eclampsia (pre-eclampsia, PE) is a unique disease during pregnancy and one of the main causes of morbidity and death in pregnant women and perinatal infants...

2021-10-12
【Animal Modeling】-Why should BALB/c mice, SD rats and cynomolgus monkey lymphocyte subsets be established?

【Animal Modeling】-Why should BALB/c mice, SD rats and cynomolgus monkey lymphocyte subsets be established?

Collect the results of the determination of peripheral blood lymphocyte subsets completed by the National Center for Drug Safety Evaluation and Monitoring during 2007-2019 in accordance with the Good Laboratory Practice (GLP) conditions of non-clinic...

2021-10-12
【Animal Modeling】-How does chronic inflammatory pain model rats induce anxiety?

【Animal Modeling】-How does chronic inflammatory pain model rats induce anxiety?

Dynamic observation of Freund\\\'s complete adjuvant (CFA)-induced changes in pain mood in rats with chronic inflammatory pain, and explore the time lag induced by anxiety and depression in rats with chronic inflammatory pain...

2021-10-12
【Animal Modeling】-How to construct Fancm knockout mice?

【Animal Modeling】-How to construct Fancm knockout mice?

To construct Fancm gene knockout mice of the Fancmi anemia pathway and study the effect of Fancm gene deletion on the physiological functions of mice, especially the physiological functions of male reproductive organs?...

2021-10-12
How to establish a pressure-overloaded heart failure mouse model? -【Animal Modeling】

How to establish a pressure-overloaded heart failure mouse model? -【Animal Modeling】

Establish a mouse heart failure model, and use ultrasound images and pathological techniques to comprehensively evaluate the characteristic changes in cardiac function and structure during the onset of the disease...

2021-10-12
【Animal Modeling】-How to build an animal model of intrauterine infection?

【Animal Modeling】-How to build an animal model of intrauterine infection?

Intrauterine infection can be invaded by various pathogens in the uterine cavity of pregnancy, causing abnormal pregnancy, neonatal diseases and other harmful consequences for the mother and baby, but the cause is unknown, so it is ineffective and th...

2021-10-12
【Animal Modeling】-How to establish a mouse bronchial asthma model?

【Animal Modeling】-How to establish a mouse bronchial asthma model?

To explore the effects of different doses of ovalbumin (OVA) on serum IgE, IL-4, IFNγ levels, bronchoalveolar lavage fluid (BALF) and eosinophils (EOS) in BALB/c mouse bronchial asthma model...

2021-10-12
【Animal Modeling】-Comparison of the similarities and differences between human and commonly used laboratory animal oral flora using 16S rRNA high-throughput sequencing method

【Animal Modeling】-Comparison of the similarities and differences between human and commonly used laboratory animal oral flora using 16S rRNA high-throughput sequencing method

The 16SRNA high-throughput sequencing method was used to determine the oral flora of several commonly used experimental animals (Tibetan miniature pigs, beagle dogs, macaques, New Zealand rabbits, Wistar rats), and compared with humans...

2021-10-12
【Animal Modeling】-Researchers used thin light beams to reorganize mouse brain cell network

【Animal Modeling】-Researchers used thin light beams to reorganize mouse brain cell network

A new study in the Science magazine shows that neurons fired at the same time are really connected in series, which shows that the \\\"three-pound computer\\\" on our heads may be more malleable than we thought...

2021-10-12
【Animal Modeling】-How to establish a SD rat model of high altitude pulmonary edema?

【Animal Modeling】-How to establish a SD rat model of high altitude pulmonary edema?

To study the effects of various hypoxic stress methods on the establishment of high altitude pulmonary edema models...

2021-10-12
【Animal Modeling】-How to establish a rat obesity model?

【Animal Modeling】-How to establish a rat obesity model?

Use a high-calorie diet to establish a rat obesity model, observe the differences between the two rat models, compare different obesity assessment methods and obesity-sensitive animal screening methods, and lose weight to provide an animal model refe...

2021-10-12
【Animal Modeling】-How to establish a salt-sensitive hypertensive mouse model?

【Animal Modeling】-How to establish a salt-sensitive hypertensive mouse model?

Establish a salt-sensitive hypertensive mouse model, and use the antihypertensive drug nifedipine to verify the model...

2021-10-12
【Animal Modeling】-How to construct human BAFF transgenic zebrafish?

【Animal Modeling】-How to construct human BAFF transgenic zebrafish?

Objective To establish a human BAFF transgenic zebrafish model and explore its role in the pathogenesis of autoimmune diseases...

2021-10-12
【Animal Modeling】-Mice experimental research helps break through new gene therapy

【Animal Modeling】-Mice experimental research helps break through new gene therapy

Researchers from the University of Tokyo in Japan used the DOK7 gene therapy method to successfully treat two neuromuscular diseases by increasing the neuromuscular junction that transmits brain signals to the muscles....

2021-10-12
[Animal modeling]-Expression and regulation of PCOS susceptibility gene Hmga2 in mouse decidualization

[Animal modeling]-Expression and regulation of PCOS susceptibility gene Hmga2 in mouse decidualization

To study the expression and regulation of PCOS susceptibility gene Hmga2 in endometrial receptivity and decidualization...

2021-10-12
【Animal Modeling】-Effects of Henggu Bone Wound Healing Agent on the Blood Physiology and Organ Coefficient of Fracture Tree Shrew

【Animal Modeling】-Effects of Henggu Bone Wound Healing Agent on the Blood Physiology and Organ Coefficient of Fracture Tree Shrew

To evaluate the effect of transverse bone wound healing agent on the blood physiological indexes and organ coefficients of Tupai castration osteoporotic fracture model...

2021-10-12