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How to prepare an animal model of rabbit atherosclerotic plaque caused by carotid artery balloon dilatation?

How to prepare an animal model of rabbit atherosclerotic plaque caused by carotid artery balloon dilatation?

Breeding method An experimental male rabbit weighing about 1.5 kg was anesthetized by intravenous injection of 25% urethane at 1 g/kg body weight, and the right common carotid artery (CCA), right internal carotid artery (ICA) and right outside of the...

2020-08-06
【Animal model】-High methionine atherosclerosis model

【Animal model】-High methionine atherosclerosis model

The male of the replication method experimental rabbit weighs 2.0 to 2.5 kg. After 15 days of adaptive feeding, feed with high methionine feed (standard rabbit feed plus 1% methionine) for 8 weeks...

2020-08-06
How to prepare a rat model of atherosclerosis induced by vitamin D?

How to prepare a rat model of atherosclerosis induced by vitamin D?

Breeding method: Male Wistar rats weighing 180-200g were injected intraperitoneally with 600,000 U/kg of vitamin D and fed with a basic diet...

2020-08-06
How to prepare animal model of macaque cerebral atherosclerosis?

How to prepare animal model of macaque cerebral atherosclerosis?

Replication method In experimental monkeys aged 10 to 16 years, 50-75 mg/kg of epinephrine was intravenously injected once a week. After the epinephrine was stopped, a high-fat diet with 1% cholesterol added 6 times for every 150 g...

2020-08-06
How to prepare quail atherosclerosis animal model?

How to prepare quail atherosclerosis animal model?

Breeding methods Male quails weigh 90-110g and are 5-6 weeks old. Feed containing 1% cholesterol, 1% lard and 1% soybean oil...

2020-08-06
How to prepare a rabbit model of atherosclerosis caused by high-fat and high-cholesterol diet?

How to prepare a rabbit model of atherosclerosis caused by high-fat and high-cholesterol diet?

Breeding method New Zealand rabbits weigh 2.0 to 2.5 kg and are about 3 to 4 months old. One week after observation, they are fed with 1.5% cholesterol 80 g/(kg to d) feed, free drinking water, and 12 animals per week. After feeding the animals for 1...

2020-08-06
【Animal model】-Hypertension model caused by medullary nerve compression

【Animal model】-Hypertension model caused by medullary nerve compression

Copy method After conventional anesthesia, the experimental dog was intubated, the right femoral artery was intubated, and the blood pressure was monitored by a multi-channel physiological recorder...

2020-08-06
[Dòngwù móxíng]-yìng jī xìng gāo xiěyā móxíng 15/5000 [Animal model]-Stress-induced hypertension model

[Dòngwù móxíng]-yìng jī xìng gāo xiěyā móxíng 15/5000 [Animal model]-Stress-induced hypertension model

Unconditional stimulation (epinephrine, angiotensin, electrical stimulation, etc.) is repeatedly combined with conditional stimulation to induce hypertension. This can be done by dogs, rats, rabbits and other animals...

2020-08-06
[Animal model]-Hypertension model caused by removal of baroreceptor afferent nerve

[Animal model]-Hypertension model caused by removal of baroreceptor afferent nerve

Refers to high blood pressure caused by blocking the aortic decompression nerve and carotid sinus nerve in animals. Dogs and rabbits are commonly used in experiments, sometimes rats...

2020-08-06
【Animal model】-Deoxycorticosterone (DOC) salt hypertension model

【Animal model】-Deoxycorticosterone (DOC) salt hypertension model

Feeding method Anesthetize the experimental rat, cut the midline of the abdomen, and remove the left kidney...

2020-08-06
【Animal Modeling】- Kidney Outsourcing Hypertension Model

【Animal Modeling】- Kidney Outsourcing Hypertension Model

Shèn wài yāpò xìng gāo xiěyā móxíng, liǎng gè shènzàng hé yīgè lǐngdài (yīgè shènzàng bēngdài, liǎng gè shènzàng dōu bǎoliú), yīgè shènzàng hé yīgè lǐngdài (yīgè shènzàng bēngdài, duì cè) shèn qiēchú shù), bìng jiāng liǎng gè shènzàng fēn wéi liǎng g...

2020-08-06
【Animal Model】-Renovascular Hypertension Model

【Animal Model】-Renovascular Hypertension Model

The renovascular hypertension model is a model in which the renal artery of an animal is narrowed to increase blood pressure. According to various test methods, two kidneys and one clamp type (the left renal artery is narrowed, both kidneys are retai...

2020-08-06
[Animal model]-Use rabbit brain powder extract to replicate the model of diffuse intravascular coagulation

[Animal model]-Use rabbit brain powder extract to replicate the model of diffuse intravascular coagulation

Preparation of rabbit brain powder injection: let the rabbit die, remove the rabbit brain, remove the attached blood vessels and meninges, and rinse with gauze...

2020-08-06
【Animal model】-Injection of polymer dextran plus calcium gluconate into the tail vein induces an early acute DIC model in rats

【Animal model】-Injection of polymer dextran plus calcium gluconate into the tail vein induces an early acute DIC model in rats

Breeding method About 200g male rats, after normal anesthesia, inject 1.5ml/100g body weight of 10% polymer dextran (HMWD, molecular weight 400,000) into the tail vein, and observe the microcirculation under a microscope 15-20 minutes later...

2020-08-06
[Animal model]-Tissue thromboplastin-induced rabbit acute DIC model

[Animal model]-Tissue thromboplastin-induced rabbit acute DIC model

The experimental rabbit body weight 2-3kg, tissue thromboplastin 20mg/kg body weight was administered to the rabbit ear vein, and the measurement was performed 1, 3, 6, 12, 24 hours before and after the tissue thromboplastin injection...

2020-08-06
[Animal model]-Rabbit DIC model induced by E. coli endotoxin

[Animal model]-Rabbit DIC model induced by E. coli endotoxin

Replication method Inject 250 μg of pathogenic E. coli endotoxin into a male New Zealand rabbit weighing about 2 kg through the ear vein...

2020-08-06